Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion

scientific article published on 2 November 2012

Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/2041731412462018
P932PMC publication ID3540750
P698PubMed publication ID23316273
P5875ResearchGate publication ID234125125

P50authorLeah A Marquez-CurtisQ45962325
Anna Janowska-WieczorekQ87734986
P2093author name stringJianping Wen
Shirley Ma
Gonzalo Hortelano
Megan Dodd
Bahareh Sayyar
P2860cites workSingle-cell hydrogel encapsulation for enhanced survival of human marrow stromal cells.Q45930948
Characterization of viability and proliferation of alginate-poly-L-lysine-alginate encapsulated myoblasts using flow cytometry.Q50444100
Migration of Bone Marrow and Cord Blood Mesenchymal Stem Cells In Vitro Is Regulated by Stromal-Derived Factor-1-CXCR4 and Hepatocyte Growth Factor-c-met Axes and Involves Matrix MetalloproteinasesQ57375767
Haemophilia B: impact on patients and economic burden of diseaseQ64041202
Human fibroblasts bind directly to fibrinogen at RGD sites through integrin alpha(v)beta3Q73320343
Comparison of cellular functionality of human mesenchymal stromal cells and PBMCQ79955430
Expansion of mesenchymal stem cells on fibrinogen-rich protein surfaces derived from blood plasmaQ84578449
Biomimetic materials for tissue engineeringQ28202115
Get a ligand, get a life: integrins, signaling and cell survivalQ28645744
Gene therapy for hemophilia.Q33838660
AnoikisQ33978500
Cell encapsulation: promise and progressQ34168860
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.Q34168942
Anoikis: roadblock to cell transplantation?Q34169271
Biocompatibility of alginate-poly-L-lysine microcapsules for cell therapyQ34507010
Molecular mechanisms of "detachment-induced apoptosis--Anoikis".Q34629157
Bioactive cell-hydrogel microcapsules for cell-based drug delivery.Q34974084
Encapsulated human mesenchymal stem cells: a unique hypoimmunogenic platform for long-term cellular therapyQ35000974
Haemophilias A and B.Q35143113
Adenovirus-associated virus vector-mediated gene transfer in hemophilia BQ35691659
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrinsQ36294082
Differential roles for alpha(M)beta(2) integrin clustering or activation in the control of apoptosis via regulation of akt and ERK survival mechanismsQ36360375
Mesenchymal stem cells: biology and clinical potential in type 1 diabetes therapyQ37094023
A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivoQ38495950
Dissimilar differentiation of mesenchymal stem cells from bone marrow, umbilical cord blood, and adipose tissue.Q40097346
Persistent delivery of factor IX in mice: gene therapy for hemophilia using implantable microcapsulesQ40948692
Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B.Q41191600
Integrins and anoikisQ41612562
Effects of plating density and culture time on bone marrow stromal cell characteristics.Q42188573
Gene therapy. Panel reviews risks of germ line changesQ43492733
Harmful potential of viral vectors fuels doubts over gene therapyQ45862715
Encapsulated human primary myoblasts deliver functional hFIX in hemophilic mice.Q45871067
Sustained and therapeutic delivery of factor IX in nude haemophilia B mice by encapsulated C2C12 myoblasts: concurrent tumourigenesis.Q45875852
Growth of recombinant fibroblasts in alginate microcapsulesQ45878839
Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cellsQ45888869
P433issue1
P921main subjectmesenchymal stem cellQ1922379
P304page(s)2041731412462018
P577publication date2012-11-02
P1433published inJournal of Tissue EngineeringQ6296005
P1476titleEncapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion
P478volume3

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cites work (P2860)
Q46334604Behaviour and ultrastructure of human bone marrow-derived mesenchymal stem cells immobilised in alginate-poly-l-lysine-alginate microcapsules
Q92074788Cell Encapsulation Within Alginate Microcapsules: Immunological Challenges and Outlook
Q38090923Encapsulated stem cells for cancer therapy
Q50995320Evaluation of different RGD ligand densities in the development of cell-based drug delivery systems.
Q28081911Gene therapy for hemophilia
Q26799475Mesenchymal stromal cells derived from various tissues: Biological, clinical and cryopreservation aspects
Q35031929Single-step laser-based fabrication and patterning of cell-encapsulated alginate microbeads
Q38982780Sustained expression of coagulation factor IX by modified cord blood-derived mesenchymal stromal cells
Q37722108Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells
Q39038615The synergistic effects of the RGD density and the microenvironment on the behavior of encapsulated cells: in vitro and in vivo direct comparative study.
Q37419249Utilizing core-shell fibrous collagen-alginate hydrogel cell delivery system for bone tissue engineering.

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