Metformin attenuates ventilator-induced lung injury

scientific article published on 24 July 2012

Metformin attenuates ventilator-induced lung injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1186/CC11439
P932PMC publication ID3580719
P698PubMed publication ID22827994
P5875ResearchGate publication ID230564350

P50authorAnastasia KotanidouQ42204471
P2093author name stringCharis Roussos
Ilias I Siempos
Apostolos Armaganidis
Petros Kopterides
Christina Magkou
George Tsaknis
Nikolaos A Maniatis
Matina Kardara
Stefania Panoutsou
P2860cites workPretreatment with atorvastatin attenuates lung injury caused by high-stretch mechanical ventilation in an isolated rabbit lung modelQ43121618
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathwayQ43158424
Metformin, but not exercise training, increases insulin responsiveness in skeletal muscle of Sprague-Dawley ratsQ43735751
Hyperglycemia at admission to the intensive care unit is associated with elevated serum concentrations of interleukin-6 and reduced ex vivo secretion of tumor necrosis factor-alphaQ44931776
Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen speciesQ44987425
Metformin decreases angiogenesis via NF-kappaB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1.Q46025973
Short-term administration of a high oxygen concentration is not injurious in an ex-vivo rabbit model of ventilator-induced lung injuryQ46158587
Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusionQ47784098
Diabetic patients have a decreased incidence of acute respiratory distress syndromeQ56287590
Validation of double vascular occlusion method for Pc,i in lung and skeletal muscleQ69570756
Effects of decreased respiratory frequency on ventilator-induced lung injuryQ73444980
Relative roles of vascular and airspace pressures in ventilator-induced lung injuryQ74373035
Interpreting the lung microvascular filtration coefficientQ80236334
Toward the prevention of acute lung injury: protocol-guided limitation of large tidal volume ventilation and inappropriate transfusionQ80347289
Prognostic influence of metformin as first-line chemotherapy for advanced nonsmall cell lung cancer in patients with type 2 diabetesQ83979505
Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?Q22241958
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitusQ24235718
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome NetworkQ27861021
Metabolic acidosis may be as protective as hypercapnic acidosis in an ex-vivo model of severe ventilator-induced lung injury: a pilot studyQ33870664
Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxicationQ33873484
Inhaled activated protein C protects mice from ventilator-induced lung injuryQ33919295
Ventilator-induced injury: from barotrauma to biotrauma.Q34480949
Metformin restores endothelial function in aorta of diabetic ratsQ34919719
Metformin-induced lactic acidosis: no one left behindQ35567151
Evaluation of lung injury in rats and miceQ35623595
Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survivalQ35688186
Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failureQ36585950
Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort studyQ37147095
Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension.Q37434434
Diabetes, insulin, and development of acute lung injuryQ37521491
Pharmacologic therapies on the horizon for acute lung injury/acute respiratory distress syndromeQ37612744
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injuryQ39935785
Ventilator-induced lung injury: lessons from experimental studiesQ41691457
Metformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs.Q42017731
Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinaseQ42075557
P433issue4
P921main subjectmetforminQ19484
ventilatorQ813243
P304page(s)R134
P577publication date2012-07-24
P1433published inCritical CareQ5186602
P1476titleMetformin attenuates ventilator-induced lung injury
P478volume16

Reverse relations

cites work (P2860)
Q37446058Activation of AMPK enhances neutrophil chemotaxis and bacterial killing
Q35625939Alterations of lung microbiota in a mouse model of LPS-induced lung injury
Q36402823Chronic obstructive pulmonary disease and glucose metabolism: a bitter sweet symphony
Q41124317Effect of Preadmission Metformin Use on Clinical Outcome of Acute Respiratory Distress Syndrome among Critically Ill Patients with Diabetes
Q33600997Human resistin promotes neutrophil proinflammatory activation and neutrophil extracellular trap formation and increases severity of acute lung injury
Q99711568Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury
Q40984750Metformin attenuates lung fibrosis development via NOX4 suppression
Q98288401Overexpression of CXCL14 Alleviates Ventilator-Induced Lung Injury through the Downregulation of PKM2-Mediated Cytokine Production
Q27013761Year in review 2012: Critical Care--Cardiology

Search more.