| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1001784054 |
| P356 | DOI | 10.1038/SJ.BJC.6690217 |
| P932 | PMC publication ID | 2362728 |
| P698 | PubMed publication ID | 10188875 |
| P5875 | ResearchGate publication ID | 13109005 |
| P2093 | author name string | Murphy G | |
| Baker AH | |||
| George SJ | |||
| Newby AC | |||
| Zaltsman AB | |||
| P2860 | cites work | Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4. | Q48048643 |
| Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues | Q48054918 | ||
| Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10. | Q48081432 | ||
| Lack of suppression of tumor cell phenotype by overexpression of TIMP-3 in mouse JB6 tumor cells identification of a transfectant with increased tumorigenicity and invasiveness. | Q53458721 | ||
| Overexpression of tissue inhibitor of matrix metalloproteinase-1 inhibits vascular smooth muscle cell functions in vitro and in vivo | Q71591023 | ||
| Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice | Q71751836 | ||
| TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells | Q73820428 | ||
| Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity | Q24300114 | ||
| The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity | Q24596245 | ||
| The tissue inhibitor of metalloproteinases-3 gene in breast carcinoma: identification of multiple polyadenylation sites and a stromal pattern of expression | Q24654930 | ||
| A novel member of human tissue inhibitor of metalloproteinases (TIMP) gene family is regulated during G1 progression, mitogenic stimulation, differentiation, and senescence | Q28245184 | ||
| Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family | Q28252820 | ||
| Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease | Q28618841 | ||
| Matrix metalloproteinases: a review | Q29620220 | ||
| Invasion of reconstituted basement membrane matrix is not correlated to the malignant metastatic cell phenotype | Q33514262 | ||
| Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues | Q34784429 | ||
| Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector | Q35068584 | ||
| Therapeutic effect of the matrix metalloproteinase inhibitor, batimastat, in a human colorectal cancer ascites model | Q36136215 | ||
| Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts | Q37292630 | ||
| Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis | Q39801237 | ||
| Development of recombinant adenoviruses that drive high level expression of the human metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 and -2 genes: characterization of their infection into rabbit smooth muscle cells and human MCF-7 a | Q41146437 | ||
| The matrix metalloproteinase inhibitor batimastat (BB-94) retards human breast cancer solid tumor growth but not ascites formation in nude mice | Q41186491 | ||
| Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice | Q41205970 | ||
| Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. | Q41435602 | ||
| Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. | Q41444177 | ||
| The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases | Q41943469 | ||
| Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues | Q42603394 | ||
| In situ detection of PCR-amplified metalloproteinase cDNAs, their inhibitors and human papillomavirus transcripts in cervical carcinoma cell lines | Q42658204 | ||
| Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion | Q42811611 | ||
| Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein | Q43526519 | ||
| Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells. | Q45887759 | ||
| Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases | Q46699016 | ||
| Tissue inhibitor of metalloproteinase-3 expression is upregulated during human cytotrophoblast invasion in vitro | Q46731706 | ||
| Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. | Q46881116 | ||
| P433 | issue | 9-10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| overexpression | Q61643320 | ||
| P304 | page(s) | 1347-1355 | |
| P577 | publication date | 1999-03-01 | |
| P1433 | published in | British Journal of Cancer | Q326309 |
| P1476 | title | Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3. | |
| P478 | volume | 79 |
| Q34210085 | A case of tumor betrayal: biphasic effects of TIMP-1 on Burkitt's lymphoma |
| Q28185858 | A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2 |
| Q36041423 | Accelerated apoptosis in the Timp-3-deficient mammary gland |
| Q45882304 | Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo |
| Q53518731 | Adenovirus carrying TIMP-3: a potential tool for cervical cancer treatment. |
| Q40756228 | Adenovirus mediated gene delivery of tissue inhibitor of metalloproteinases-3 induces death in retinal pigment epithelial cells |
| Q36695822 | An immunohistochemical study of TIMP-3 expression in oesophageal squamous cell carcinoma |
| Q37827399 | Angiogenesis and invasion in glioma |
| Q47131124 | Antcin-H Isolated from Antrodia cinnamomea Inhibits Renal Cancer Cell Invasion Partly through Inactivation of FAK-ERK-C/EBP-β/c-Fos-MMP-7 Pathways. |
| Q93353440 | Antiangiogenic Gene Therapy in Cancer |
| Q39418968 | Antimetastatic effects and mechanisms of apo-8'-lycopenal, an enzymatic metabolite of lycopene, against human hepatocarcinoma SK-Hep-1 cells |
| Q36292643 | Are fibroblasts involved in joint destruction? |
| Q34155848 | Bone marrow microenvironment in myelomagenesis: its potential role in early diagnosis |
| Q34876809 | Cell surface-bound TIMP3 induces apoptosis in mesenchymal Cal78 cells through ligand-independent activation of death receptor signaling and blockade of survival pathways |
| Q44131334 | Comparative study of the expression of metalloproteases and their inhibitors in different localizations within primary tumours and in metastatic lymph nodes of breast cancer |
| Q36439161 | Comparison of localized versus systemic levels of Matrix metalloproteinases (MMPs), its tissue inhibitors (TIMPs) and cytokines in tuberculous and non-tuberculous pleuritis patients |
| Q34596110 | Complex roles of tissue inhibitors of metalloproteinases in cancer |
| Q36192139 | Contribution of TIMP3 polymorphisms to the development of preeclampsia in Han Chinese women |
| Q92134637 | Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics |
| Q80604675 | Differences between scirrhous and non-scirrhous human gastric carcinomas from the aspect of proMMP-2 activation regulated by TIMP-3 |
| Q54504438 | Different regulation of tissue inhibitors of metalloproteinases-1, -2 and -3 in human endometrial stromal cells during decidualization in vitro. |
| Q39063857 | Differential TIMP3 expression affects tumor progression and angiogenesis in melanomas through regulation of directionally persistent endothelial cell migration |
| Q38101685 | Does mammographic density reflect the expression of breast cancer markers? |
| Q40528099 | Down-regulation and promoter methylation of tissue inhibitor of metalloproteinase 3 in choriocarcinoma. |
| Q37338894 | Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity. |
| Q37205264 | Epigenetic modification suppresses proliferation, migration and invasion of urothelial cancer cell lines. |
| Q45326725 | Evidence for involvement of TNFR1 and TIMPs in pathogenesis of post-kala-azar dermal leishmaniasis |
| Q40753407 | Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis |
| Q84907028 | Expression of metalloproteases and their inhibitors in different histological types of breast cancer |
| Q82364258 | Expression of metalloproteases and their inhibitors in primary tumors and in local recurrences after mastectomy for breast cancer |
| Q35605873 | Expression of tissue inhibitor of matrix metalloproteinases (TIMP)-3 protein in invasive breast carcinoma: relation to tumor phenotype and clinical outcome |
| Q35800580 | Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. |
| Q89617856 | Feeling Things Out: Bidirectional Signaling of the Cell-ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation |
| Q63456989 | Fibroblasts from the muscles of Duchenne muscular dystrophy patients are resistant to cell detachment apoptosis |
| Q40356020 | GPI-anchored TIMP-1 treatment renders renal cell carcinoma sensitive to FAS-meditated killing |
| Q40644810 | Gene therapy for hepatocellular carcinoma using non-viral vectors composed of bis guanidinium-tren-cholesterol and plasmids encoding the tissue inhibitors of metalloproteinases TIMP-2 and TIMP-3. |
| Q91756413 | Genome-wide ChIP-seq data with a transcriptome analysis reveals the groups of genes regulated by histone demethylase LSD1 inhibition in esophageal squamous cell carcinoma cells |
| Q35225620 | Genome-wide expression analysis suggests a crucial role of dysregulation of matrix metalloproteinases pathway in undifferentiated thyroid carcinoma |
| Q34102569 | Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta. |
| Q54572474 | HGF/c-Met overexpressions, but not met mutation, correlates with progression of non-small cell lung cancer. |
| Q81094520 | High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas |
| Q40569139 | Identification of genes that are regulated transcriptionally by Myc in childhood tumors |
| Q38206794 | Illustrating the interplay between the extracellular matrix and microRNAs. |
| Q51565984 | In vitro evaluation of anticancer properties of exopolysaccharides from Lactobacillus acidophilus in colon cancer cell lines. |
| Q40318346 | Individual Timp deficiencies differentially impact pro-MMP-2 activation |
| Q39880055 | Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation |
| Q40352526 | Inhibition of human leukemia xenograft in nude mice by adenovirus-mediated tissue inhibitor of metalloproteinase-3. |
| Q39792473 | Inhibition of tumor growth and induction of apoptosis in prostate cancer cell lines by overexpression of tissue inhibitor of matrix metalloproteinase-3. |
| Q38929199 | Knockdown of the AKT3 (PKBγ), PI3KCA, and VEGFR2 genes by RNA interference suppresses glioblastoma multiforme T98G cells invasiveness in vitro |
| Q28570779 | Localization and expression of tissue inhibitor of metalloproteinase-4 in the immature gonadotropin-stimulated and adult rat ovary |
| Q46150179 | Low microvascular density at the tumor center is related to the expression of metalloproteases and their inhibitors and with the occurrence of distant metastasis in breast carcinomas. |
| Q39938314 | Low tissue inhibitor of metalloproteinases 3 and high matrix metalloproteinase 14 levels defines a subpopulation of highly invasive foam-cell macrophages |
| Q36312729 | MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line |
| Q34268721 | Mammographic density and matrix metalloproteinases in breast tissue |
| Q43817798 | Matrix metalloproteinase and tissue inhibitors of metalloproteinase secretion by haematopoietic and stromal precursors and their production in normal and leukaemic long-term marrow cultures. |
| Q34244468 | Matrix metalloproteinases and their tissue inhibitors - expression, role and regulation in human malignant non-Hodgkin's lymphomas |
| Q36752100 | Matrix metalloproteinases: influence on smooth muscle cells and atherosclerotic plaque stability |
| Q35587684 | Membrane associated proteases and their inhibitors in tumour angiogenesis |
| Q24803225 | Metalloproteinases: role in breast carcinogenesis, invasion and metastasis |
| Q34768858 | Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? |
| Q33585105 | Micro-RNAs as clinical biomarkers and therapeutic targets in breast cancer: Quo vadis? |
| Q24336898 | MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators |
| Q33784804 | MicroRNA-21 regulates breast cancer invasion partly by targeting tissue inhibitor of metalloproteinase 3 expression |
| Q34338088 | Multiple points of intervention in the prevention of cancer and other mutation-related diseases |
| Q35617336 | Ovarian expression, localization, and function of tissue inhibitor of metalloproteinase 3 (TIMP3) during the periovulatory period of the human menstrual cycle |
| Q36611308 | Overexpression of matrix metalloproteinases and their inhibitors in mononuclear inflammatory cells in breast cancer correlates with metastasis-relapse |
| Q40795795 | Phenotypic alterations in Caki-1 cells as a consequence of TIMP-1 overexpression. |
| Q37351433 | Polymorphisms in tissue inhibitors of metalloproteinases-2 and -3 and breast cancer susceptibility and survival |
| Q34030512 | Potential applications of gene therapy in the patient with cancer |
| Q54462431 | Predicting invasive phenotype with CDH1, CDH13, CD44, and TIMP3 gene expression in primary breast cancer. |
| Q52838958 | Profile of Metalloproteinases and Their Association with Inflammatory Markers in Pleural Effusions. |
| Q44037768 | Promoter hypomethylation of TIMP3 is associated with pre-eclampsia in a Chinese population |
| Q38823174 | Proteases as prognostic markers in human and canine cancers |
| Q34533127 | Proteinase activity regulation by glycosaminoglycans |
| Q74248845 | Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression |
| Q40781214 | Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression |
| Q40663909 | Retroviral vector-producer cell-mediated in vivo gene transfer of TIMP-3 restricts angiogenesis and neuroblastoma growth in mice |
| Q39551235 | Rosiglitazone and retinoic acid inhibit proliferation and induce apoptosis in the HCT-15 human colorectal cancer cell line |
| Q38340761 | Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma |
| Q57168304 | Sorsby fundus dystrophy: Insights from the past and looking to the future |
| Q44174063 | Sorsby's fundus dystrophy mutant tissue inhibitors of metalloproteinase-3 induce apoptosis of retinal pigment epithelial and MCF-7 cells |
| Q36041136 | Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). |
| Q34810420 | Strategies for MMP inhibition in cancer: innovations for the post-trial era. |
| Q24315151 | Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex |
| Q44530445 | TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism |
| Q92277219 | TIMP-3 as a therapeutic target for cancer |
| Q30886270 | TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix |
| Q53687206 | TIMP3 Overexpression Improves the Sensitivity of Osteosarcoma to Cisplatin by Reducing IL-6 Production. |
| Q90533467 | TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis |
| Q37580093 | The effect of hypothermia on the expression of TIMP-3 after traumatic brain injury in rats |
| Q28215674 | The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs |
| Q38014071 | The gelatinases and their inhibitors: the structure-activity relationships |
| Q28583507 | The glycoprotein fibulin-3 regulates morphology and motility of olfactory ensheathing cells in vitro |
| Q33776177 | The potential for gene therapy in pancreatic cancer |
| Q36350978 | The role of matrix metalloproteinases (MMPs) in human caries |
| Q33786342 | The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity |
| Q37781917 | Therapeutic opportunities in fibroblasts in inflammatory arthritis |
| Q52332324 | Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells. |
| Q43150815 | Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age. |
| Q44321303 | Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons |
| Q36981838 | Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer |
| Q44540466 | Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells against intrinsic apoptotic cell death via the focal adhesion kinase/phosphatidylinositol 3-kinase and MAPK signaling pathway |
| Q35152040 | Tissue inhibitor of metalloproteinase-3 (TIMP3) promotes endothelial apoptosis via a caspase-independent mechanism |
| Q40752756 | Tissue inhibitor of metalloproteinase-3 induces a Fas-associated death domain-dependent type II apoptotic pathway |
| Q44574077 | Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosis |
| Q81504443 | Tissue inhibitor of metalloproteinases-3 facilitates Fas-mediated neuronal cell death following mild ischemia |
| Q64377824 | Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors |
| Q24311632 | Tissue inhibitor of metalloproteinases-3 interacts with angiotensin II type 2 receptor and additively inhibits angiogenesis |
| Q39265667 | Tissue inhibitor of metalloproteinases-3 transfer suppresses malignant behaviors of colorectal cancer cells |
| Q36805538 | Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. |
| Q28138083 | Tissue inhibitors of metalloproteinases: evolution, structure and function |
| Q28235218 | Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme |
| Q50354240 | Tumor progression driven by pathways activating matrix metalloproteinases and their inhibitors. |
| Q39163973 | Ultrasound-targeted HSVtk and Timp3 gene delivery for synergistically enhanced antitumor effects in hepatoma. |
| Q43510716 | alpha 1-Proteinase inhibitor, alpha 1-antichymotrypsin, and alpha 2-macroglobulin are the antiapoptotic factors of vascular smooth muscle cells |
| Q38739495 | miR-21 Might be Involved in Breast Cancer Promotion and Invasion Rather than in Initial Events of Breast Cancer Development. |
| Q34931601 | miR-21: a small multi-faceted RNA. |
| Q26824561 | miRNAs in breast cancer tumorigenesis (Review) |
| Q36084306 | microRNA-103 regulates the growth and invasion of endometrial cancer cells through the downregulation of tissue inhibitor of metalloproteinase 3. |
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