Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis

scientific article published on 19 January 2017

Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2016-09-742999
P932PMC publication ID5408561
P698PubMed publication ID28104688

P50authorSteve P. WatsonQ37383398
Alexander BrillQ42290283
P2093author name stringHolly Payne
Tatyana Ponomaryov
P2860cites workNeutrophil extracellular traps promote deep vein thrombosis in miceQ24604984
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumorsQ24675750
Platelets in inflammation: regulation of leukocyte activities and vascular repairQ26852677
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Neutrophil extracellular traps kill bacteriaQ27860996
Podoplanin: emerging functions in development, the immune system, and cancerQ28275310
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2Q28297782
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veinsQ28507544
G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciencesQ29547562
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitectureQ30090178
Inflammation induces hemorrhage in thrombocytopeniaQ30481913
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.Q30514065
Extrahepatic high-density lipoprotein receptor SR-BI and apoA-I protect against deep vein thrombosis in mice.Q30528268
Platelet ITAM signaling is critical for vascular integrity in inflammationQ33405485
Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopeniaQ33424357
Laser-induced endothelial cell activation supports fibrin formationQ33646447
The epidemiology of venous thromboembolism in the communityQ33865646
Secular trends in occurrence of acute venous thromboembolism: the Worcester VTE study (1985-2009)Q34167655
Thrombosis as an intravascular effector of innate immunityQ34316343
von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse modelsQ34666946
Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in AtherothrombosisQ35791685
Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growthQ35832431
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Q35894194
Microvascular thrombosis models in venules and arterioles in vivo.Q36090998
Inflammation drives thrombosis after Salmonella infection via CLEC-2 on plateletsQ36335932
Neutrophil extracellular trap (NET) impact on deep vein thrombosisQ36391500
The structure and growth of valve-pocket thrombi in femoral veinsQ36580916
Pathogenesis of primary chronic venous disease: Insights from animal models of venous hypertensionQ37051895
CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils.Q37307300
Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservationQ37350527
Basic mechanisms and pathogenesis of venous thrombosisQ37388336
Platelet immunoreceptor tyrosine-based activation motif (ITAM) and hemITAM signaling and vascular integrity in inflammation and developmentQ38691519
Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroidsQ39656658
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.Q39821682
The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory stateQ42070099
Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesisQ42445347
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets.Q42582678
CLEC-2 is not required for platelet aggregation at arteriolar shearQ42942640
Interleukin-8 administration enhances venous thrombosis resolution in a rat modelQ43649957
IL-10 regulates thrombus-induced vein wall inflammation and thrombosisQ47756955
Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice.Q51828070
Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing.Q52085270
Openings in frog microvascular endothelium induced by high intravascular pressuresQ71323328
The PO2 in venous valve pockets: its possible bearing on thrombogenesisQ71506959
Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wallQ80512468
CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosisQ84313347
P4510describes a project that usesImageJQ1659584
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectthrombosisQ261327
P304page(s)2013-2020
P577publication date2017-01-19
P1433published inBloodQ885070
P1476titleMice with a deficiency in CLEC-2 are protected against deep vein thrombosis
P478volume129

Reverse relations

cites work (P2860)
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