GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity

scientific article published on 28 March 2017

GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.16585
P932PMC publication ID5522090
P698PubMed publication ID28388560

P50authorChia-Lang HsuQ57563516
P2093author name stringHsueh-Fen Juan
Chi-Hau Chen
Ho-Hsiung Lin
Min-Chuan Huang
John Huang
Tzu-Chi Lin
Syue-Ting Chen
P2860cites workARID1A mutations in endometriosis-associated ovarian carcinomasQ24610484
Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene familyQ26864268
Cancer statistics, 2014Q27861018
Clear cell carcinoma of the ovary: a review of the literatureQ28265125
Type-specific cell line models for type-specific ovarian cancer researchQ28536689
Integration of biological networks and gene expression data using CytoscapeQ28681323
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.Q34006269
Glycosylation defining cancer malignancy: new wine in an old bottleQ34074081
Polypeptide N-acetylgalactosaminyltransferase 6 disrupts mammary acinar morphogenesis through O-glycosylation of fibronectinQ34763642
Polypeptide N-acetylgalactosaminyltransferase 6 expression in pancreatic cancer is an independent prognostic factor indicating better overall survivalQ35034722
Global distribution pattern of histological subtypes of epithelial ovarian cancer: a database analysis and systematic reviewQ35099083
Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signalingQ35742375
New perspectives on molecular targeted therapy in ovarian clear cell carcinoma.Q36889642
Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group StudyQ36912591
Morphological and Immunohistochemical Reevaluation of Tumors Initially Diagnosed as Ovarian Endometrioid Carcinoma With Emphasis on High-grade Tumors.Q37196721
Targeting the epidermal growth factor receptor in epithelial ovarian cancer: current knowledge and future challenges.Q37485865
Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylationQ37660331
The extended ppGalNAc-T family and their functional involvement in the metastatic cascadeQ38150732
Insulin-like growth factor binding protein-3 (IGFBP-3) acts as an invasion-metastasis suppressor in ovarian endometrioid carcinoma.Q38297113
GALNT2 enhances migration and invasion of oral squamous cell carcinoma by regulating EGFR glycosylation and activityQ38308686
Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 KnockdownQ38767655
The Dualistic Model of Ovarian Carcinogenesis: Revisited, Revised, and ExpandedQ38787667
MUC20 promotes aggressive phenotypes of epithelial ovarian cancer cells via activation of the integrin β1 pathwayQ38816028
The mucin-type glycosylating enzyme polypeptide N-acetylgalactosaminyltransferase 14 promotes the migration of ovarian cancer by modifying mucin 13.Q39147421
MUC20 overexpression predicts poor prognosis and enhances EGF-induced malignant phenotypes via activation of the EGFR-STAT3 pathway in endometrial cancerQ39221819
Mucin glycosylating enzyme GALNT2 regulates the malignant character of hepatocellular carcinoma by modifying the EGF receptorQ39459644
Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesisQ39730101
Expression of MUC1 in primary and metastatic human epithelial ovarian cancer and its therapeutic significanceQ79972618
Invasion patterns in stage I endometrioid and mucinous ovarian carcinomas: a clinicopathologic analysis emphasizing favorable outcomes in carcinomas without destructive stromal invasion and the occasional malignant course of carcinomas with limitedQ81370832
Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinomaQ83139511
P4510describes a project that usesCytoscapeQ3699942
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
P304page(s)42588-42601
P577publication date2017-03-28
P1433published inOncotargetQ1573155
P1476titleGALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity
P478volume8

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cites work (P2860)
Q58757254Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells
Q53690855GALNT14 Involves the Regulation of Multidrug Resistance in Breast Cancer Cells.
Q94562112GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78
Q60921914GALNT6 suppresses progression of colorectal cancer
Q49805726Glycosylation as a Main Regulator of Growth and Death Factor Receptors Signaling
Q52369544Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation.
Q98164379Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence
Q91890334The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression

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