Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis

scientific article published on 27 June 2017

Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.18621
P932PMC publication ID5620175
P698PubMed publication ID28978035

P2093author name stringYing Zhou
Xiao Wei
Fei Li
Ding Ma
Jin Jiang
Rui Wei
Ling Xi
Xiangyi Ma
Danfeng Luo
Guiying Jiang
Jicheng Lou
Mengqin Lv
Ruiqiu Gao
Teng Cheng
Xizi Wu
Zhengzhong Zhang
P2860cites workCan advanced-stage ovarian cancer be cured?Q38703522
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Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblastsQ39098568
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Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric CancerQ39462770
Hedgehog signaling pathway regulates the growth of ovarian cancer spheroid forming cellsQ39518994
Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.Q43639734
Tumor-associated macrophages in SHH subgroup of medulloblastomasQ46117209
Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancerQ53040486
A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis.Q53237550
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Hedgehog signaling: modulation of cancer properies and tumor mircroenvironmentQ26764740
Pressing the right buttons: signaling in lymphangiogenesisQ27006947
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Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancerQ27307642
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A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFRQ33835932
VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-regulation of BRCA1 and BRCA2.Q33891251
Serum Vascular Endothelial Growth Factor (VEGF-C) as a Diagnostic and Prognostic Marker in Patients with Ovarian CancerQ34577121
Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cellsQ35793591
The biology of vascular endothelial growth factors.Q36017169
Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathwayQ36759752
GLI1 finds a new role in cancer stem cell biologyQ36771311
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.Q36861965
Human carcinoma-associated mesenchymal stem cells promote ovarian cancer chemotherapy resistance via a BMP4/HH signaling loop.Q36916375
MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis.Q37437254
Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretionQ37716611
Hedgehog signaling: networking to nurture a promalignant tumor microenvironmentQ37903167
Ovarian, fallopian tube and peritoneal cancer staging: Rationale and explanation of new FIGO staging 2013.Q38428317
Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironmentQ38567779
P433issue40
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
lymphangiogenesisQ6708231
P304page(s)67315-67328
P577publication date2017-06-27
P1433published inOncotargetQ1573155
P1476titleHuman CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis
P478volume8

Reverse relations

cites work (P2860)
Q58101680Cancer Associated Fibroblasts: Naughty Neighbors That Drive Ovarian Cancer Progression
Q99551760Cancer-associated fibroblasts, matrix metalloproteinase-9 and lymphatic vessel density are associated with progression from adenocarcinoma in situ to invasive adenocarcinoma of the lung
Q88506161Dual-Targeted Microbubbles Specific to Integrin αVβ3 and Vascular Endothelial Growth Factor Receptor 2 for Ultrasonography Evaluation of Tumor Angiogenesis
Q89715674Expression of long noncoding RNAs in cancer-associated fibroblasts linked to patient survival in ovarian cancer
Q47112522Gastric metastasis from ovarian adenocarcinoma presenting as a subepithelial tumor and diagnosed by endoscopic ultrasound-guided tissue acquisition
Q92331139Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer
Q91980576Lymphatic vasculature in tumor metastasis and immunobiology
Q104073561Metabolomics revealed the influence of breast cancer on lymphatic endothelial cell metabolism, metabolic crosstalk, and lymphangiogenic signaling in co-culture
Q64916848Sonic Hedgehog Ligand: A Role in Formation of a Mesenchymal Niche in Human Pancreatic Ductal Adenocarcinoma.
Q58771105Sonic hedgehog promotes endothelial differentiation of bone marrow mesenchymal stem cells via VEGF-D
Q92027212The Role of Cancer Stem Cells and Mechanical Forces in Ovarian Cancer Metastasis
Q99591486The Role of Cancer-Associated Fibroblasts and Extracellular Vesicles in Tumorigenesis
Q92921970The Role of Dermal Fibroblasts in Nevoid Basal Cell Carcinoma Syndrome Patients: An Overview
Q90452290The Tumor Microenvironment of Epithelial Ovarian Cancer and Its Influence on Response to Immunotherapy
Q100694552VEGFC negatively regulates the growth and aggressiveness of medulloblastoma cells

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