Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium

scientific article published on 16 October 2017

Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-017-13746-W
P932PMC publication ID5643391
P698PubMed publication ID29038523

P50authorMarco Matucci-CerinicQ19859583
Eloisa RomanoQ92547424
Felice GalluccioQ96024292
Riccardo TerenziQ114309912
Mirko ManettiQ47143114
Lidia Ibba-ManneschiQ47265756
Serena GuiducciQ47265812
P2093author name stringSerena Guiducci
Irene Rosa
P2860cites workRole of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury.Q51140106
Angiotensin II protects fibroblast-like synoviocytes from apoptosis via the AT1-NF-kappaB pathway.Q53550461
A clinical and biochemical assessment of a nonthiol ACE inhibitor (pentopril; CGS-13945) in active rheumatoid arthritisQ68827906
Captopril: a new treatment for rheumatoid arthritis?Q72580522
Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis and antagonizes angiotensin II type 1 receptor action: an in vitro gene transfer studyQ77525064
Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosisQ78744711
Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitisQ79695004
Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritisQ80182570
Angiotensin receptor blockers reduce erythrocyte sedimentation rate levels in patients with rheumatoid arthritisQ82294472
Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritisQ24598633
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 updateQ26859134
Angiotensin II in inflammation, immunity and rheumatoid arthritisQ26991828
Angiotensin II type 2 receptor mediates programmed cell deathQ28272739
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptorsQ28364369
Role of the angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker ratsQ28571720
The pathogenesis of rheumatoid arthritisQ29614957
A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetesQ30300953
Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarctionQ30309594
The angiotensin II type 2 receptor and improved adjacent region function post-MI.Q30436784
Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulationQ33205413
Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cellsQ33600747
The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the AT1 receptor: gain-of-function study using gene transferQ33792965
Expressions of local renin-angiotensin system components in chondrocytesQ33851298
Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severityQ34238357
The AT2 receptor--a matter of love and hateQ34436809
Ligand-independent signals from angiotensin II type 2 receptor induce apoptosisQ34731369
Role of the renin-angiotensin system in vascular inflammationQ34789029
Protective effects of angiotensin II interruption: evidence for antiinflammatory actionsQ36257966
The angiotensin II type 2 (AT2) receptor promotes axonal regeneration in the optic nerve of adult ratsQ36404036
Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivoQ36546985
Angiotensin AT2 receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages via increased interleukin-10 productionQ36981859
Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritisQ37557554
High risk of clinical cardiovascular events in rheumatoid arthritis: Levels of associations of myocardial infarction and stroke through a systematic review and meta-analysisQ37775403
The angiotensin II type 2 receptor agonist Compound 21 is protective in experimental diabetes-associated atherosclerosis.Q38771740
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB.Q39900531
Effect of simultaneous blockade of AT1 and AT2 receptors on the NFkappaB pathway and renal inflammatory response.Q40562942
Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?Q41206012
Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritisQ42165744
Effect of AT2 receptor on expression of AT1 and TGF-beta receptors in VSMCs from SHR.Q42528495
Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null miceQ46689553
Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive ratsQ46884693
Angiotensin II type 2 receptor is upregulated in human heart with interstitial fibrosis, and cardiac fibroblasts are the major cell type for its expressionQ48350568
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
P304page(s)13293
P577publication date2017-10-16
P1433published inScientific ReportsQ2261792
P1476titleAngiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium
P478volume7

Reverse relations

cites work (P2860)
Q90305559Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
Q58732246Angiotensin IV suppresses inflammation in the brains of rats with chronic cerebral hypoperfusion
Q51737917Morphological evidence of telocytes in human synovium.
Q97074100Role of the Backbenchers of the Renin-Angiotensin System ACE2 and AT2 Receptors in COVID-19: Lessons From SARS
Q108591796Role of the Renin–Angiotensin–Aldosterone and Kinin–Kallikrein Systems in the Cardiovascular Complications of COVID-19 and Long COVID

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