Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

scientific article published on 30 September 2009

Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JCBFM.2009.205
P932PMC publication ID2949091
P698PubMed publication ID19794397
P5875ResearchGate publication ID26861011

P50authorBertrand TavitianQ39407817
Abraham MartínQ42414846
Nadja Van CampQ42414849
P2093author name stringFrédéric Dollé
Michael Kassiou
Raphaël Boisgard
Benoit Thézé
Bertrand Kuhnast
Annelaure Damont
P2860cites workTranslocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular functionQ24296269
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologiesQ24642726
Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repairQ24644752
Microglia: a sensor for pathological events in the CNSQ29620556
Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195.Q33924062
Steroid synthesis and metabolism in the nervous system: trophic and protective effectsQ34292714
DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterizationQ34769959
Mitochondrial apoptosis and the peripheral benzodiazepine receptor: a novel target for viral and pharmacological manipulationQ34989649
Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.Q37283568
[11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitisQ41863477
Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue.Q43552483
In-vivo measurement of activated microglia in dementiaQ43713539
Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: relation to infarct growth and neuroprotection.Q44699102
Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localizationQ44833711
Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammationQ46119208
Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptorQ48150670
A template for spatial normalisation of MR images of the rat brainQ48188086
Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in ratsQ48189477
Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.Q48504474
[3H]PK 11195 and the localisation of secondary thalamic lesions following focal ischaemia in rat motor cortexQ48622683
Brain kinetics and specific binding of [11C]PK 11195 to omega 3 sites in baboons: positron emission tomography study.Q48674057
Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesionQ48783677
Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in ratsQ48863137
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.Q51428685
Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the ratQ71924070
In vivo imaging of activated microglia using [11C]PK11195 and positron emission tomography in patients after ischemic strokeQ73008849
The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activityQ73119445
Anti-VCAM-1 antibodies did not protect against ischemic damage either in rats or in miceQ81003728
Evolution of microglial activation in patients after ischemic stroke: a [11C](R)-PK11195 PET studyQ81218861
P4510describes a project that usesImageQuantQ112270642
P433issue1
P921main subjectcerebral infarctionQ1209150
P304page(s)230-241
P577publication date2009-09-30
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleEvaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia
P478volume30