Control of AmtB-GlnK complex formation by intracellular levels of ATP, ADP, and 2-oxoglutarate

scientific article published on 18 July 2010

Control of AmtB-GlnK complex formation by intracellular levels of ATP, ADP, and 2-oxoglutarate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.153908
P932PMC publication ID2945594
P698PubMed publication ID20639578

P2093author name stringMike Merrick
Martha V Radchenko
Jeremy Thornton
P2860cites workConstruction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collectionQ22122301
Rh type B glycoprotein is a new member of the Rh superfamily and a putative ammonia transporter in mammalsQ24290376
Specificity and regulation of interaction between the PII and AmtB1 proteins in Rhodospirillum rubrumQ24671952
Inhibitory complex of the transmembrane ammonia channel, AmtB, and the cytosolic regulatory protein, GlnK, at 1.96 AQ27640959
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptakeQ27641055
The crystal structure of the Escherichia coli AmtB-GlnK complex reveals how GlnK regulates the ammonia channelQ27641125
Structural basis for the regulation of N-acetylglutamate kinase by PII in Arabidopsis thalianaQ27648704
The crystal structure of the complex of PII and acetylglutamate kinase reveals how PII controls the storage of nitrogen as arginineQ27648888
Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtBQ27650147
A new P(II) protein structure identifies the 2-oxoglutarate binding siteQ27661798
GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognitionQ27765291
Use of T7 RNA polymerase to direct expression of cloned genesQ27860692
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Interaction of the signal transduction protein GlnJ with the cellular targets AmtB1, GlnE and GlnD in Rhodospirillum rubrum: dependence on manganese, 2-oxoglutarate and the ADP/ATP ratioQ28289088
A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genesQ29547324
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coliQ29615316
Ternary complex formation between AmtB, GlnZ and the nitrogenase regulatory enzyme DraG reveals a novel facet of nitrogen regulation in bacteriaQ33306597
Regulation of autophosphorylation of Escherichia coli nitrogen regulator II by the PII signal transduction proteinQ33991527
Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.Q34347544
The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coliQ34371143
The ammonia channel protein AmtB from Escherichia coli is a polytopic membrane protein with a cleavable signal peptide.Q34516161
In vitro analysis of the Escherichia coli AmtB-GlnK complex reveals a stoichiometric interaction and sensitivity to ATP and 2-oxoglutarateQ34550641
An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductanceQ34573855
PII signal transduction proteins: sensors of alpha-ketoglutarate that regulate nitrogen metabolismQ36085261
Adenylate energy charge in Escherichia coli during growth and starvationQ36774259
P(II) signal transducers: novel functional and structural insightsQ37053264
Metabolomics-driven quantitative analysis of ammonia assimilation in E. coliQ37330224
Membrane sequestration of the signal transduction protein GlnK by the ammonium transporter AmtB.Q38292054
Role of Escherichia coli nitrogen regulatory genes in the nitrogen response of the Azotobacter vinelandii NifL-NifA complexQ39503556
General method, using Mu-Mud1 dilysogens, to determine the direction of transcription of and generate deletions in the glnA region of Escherichia coliQ39974109
Sensation and signaling of alpha-ketoglutarate and adenylylate energy charge by the Escherichia coli PII signal transduction protein require cooperation of the three ligand-binding sites within the PII trimerQ42106200
In vivo functional characterization of the Escherichia coli ammonium channel AmtB: evidence for metabolic coupling of AmtB to glutamine synthetaseQ42109194
Effect of perturbation of ATP level on the activity and regulation of nitrogenase in Rhodospirillum rubrumQ43071788
The PII superfamily revised: a novel group and evolutionary insights.Q44225791
Ammonium sensing in Escherichia coli. Role of the ammonium transporter AmtB and AmtB-GlnK complex formationQ44688352
Relationship between growth rate and ATP concentration in Escherichia coli: a bioassay for available cellular ATP.Q44690070
Escherichia coli PII signal transduction protein controlling nitrogen assimilation acts as a sensor of adenylate energy charge in vitroQ46948165
The Escherichia coli AmtB protein as a model system for understanding ammonium transport by Amt and Rh proteinsQ47603454
Covalent modification of bacterial glutamine synthetase: physiological significanceQ50209962
Acidic acetonitrile for cellular metabolome extraction from Escherichia coli.Q54438002
The Escherichia coli PII Signal Transduction Protein Is Activated upon Binding 2-Ketoglutarate and ATPQ54608056
The glnKamtB operonQ62516530
Biological function of the ammonia-induced inactivation of glutamine synthetase in Escherichia coliQ68766181
Heterotrimerization of PII-like signalling proteins: implications for PII-mediated signal transduction systemsQ78016783
Effect of AmtB homologues on the post-translational regulation of nitrogenase activity in response to ammonium and energy signals in Rhodospirillum rubrumQ79801356
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)31037-31045
P577publication date2010-07-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleControl of AmtB-GlnK complex formation by intracellular levels of ATP, ADP, and 2-oxoglutarate
P478volume285

Reverse relations

cites work (P2860)
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