Ghrelin increases GABAergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala

scientific article published on 12 September 2012

Ghrelin increases GABAergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1053023915
P356DOI10.1038/NPP.2012.190
P932PMC publication ID3527109
P698PubMed publication ID22968812
P5875ResearchGate publication ID230833272

P2093author name stringAndrey E Ryabinin
Dawn M Cote
Marisa Roberto
Maureen T Cruz
Melissa A Herman
P2860cites workGhrelin is a growth-hormone-releasing acylated peptide from stomachQ22010951
A receptor in pituitary and hypothalamus that functions in growth hormone releaseQ24308321
Requirement of central ghrelin signaling for alcohol rewardQ24656030
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.Q33904853
Ghrelin receptor antagonism decreases alcohol consumption and activation of perioculomotor urocortin-containing neuronsQ34088378
The role of the central ghrelin system in reward from food and chemical drugsQ34167084
Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptorsQ34303326
Type 7 Adenylyl Cyclase is Involved in the Ethanol and CRF Sensitivity of GABAergic Synapses in Mouse Central AmygdalaQ34505367
Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilinQ34513044
A role of ghrelin in neuroendocrine and behavioral responses to stress in miceQ34517302
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissuesQ34743649
Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neuronsQ34763227
Alcoholism: allostasis and beyondQ35073089
Alcoholism and obesity: overlapping neuropeptide pathways?Q35617839
Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents.Q35658705
Expression of ghrelin receptor mRNA in the rat and the mouse brainQ35915057
Protein kinase C epsilon mediation of CRF- and ethanol-induced GABA release in central amygdalaQ36751542
Alcoholism, craving, and hormones: the role of leptin, ghrelin, prolactin, and the pro-opiomelanocortin system in modulating ethanol intakeQ37012155
Ghrelin system in alcohol-dependent subjects: role of plasma ghrelin levels in alcohol drinking and craving.Q37153644
Nociceptin/orphanin FQ blockade of corticotropin-releasing factor-induced gamma-aminobutyric acid release in central amygdala is enhanced after chronic ethanol exposure.Q37336909
Role of feeding-related pathways in alcohol dependence: A focus on sweet preference, NPY, and ghrelinQ37807998
Short-term synaptic plasticityQ38613257
Reward-related genes and personality traits in alcohol-dependent individuals: a pilot case control studyQ39747166
Neurocircuitry targets in ethanol reward and dependenceQ40865875
Genetic variation of the ghrelin signaling system in females with severe alcohol dependenceQ43002249
Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid dietsQ44043558
Quantitative autoradiography of mu-opioid receptors in the CNS of alcohol-naive alcohol-preferring P and -nonpreferring NP ratsQ44350583
Increased fasting plasma ghrelin levels during alcohol abstinenceQ45133907
Increased GABA release in the central amygdala of ethanol-dependent rats.Q45146982
Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicksQ45176388
Modulation of synaptic transmission and long-term potentiation: effects on paired pulse facilitation and EPSC variance in the CA1 region of the hippocampusQ46152163
Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body massQ46337111
Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats.Q46529874
Noise analysis of miniature IPSCs in adult rat brain slices: properties and modulation of synaptic GABAA receptor channelsQ46610491
Alcohol dependence is associated with reduced plasma and fundic ghrelin levelsQ46636193
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.Q46853928
Ghrelin levels are increased in alcoholismQ46872742
Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile rats: an in vitro studyQ47840476
Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in ratsQ48030567
Paired-pulse facilitation in the dentate gyrus: a patch-clamp study in rat hippocampus in vitroQ48097388
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasisQ48382703
Electrophysiological effects of ghrelin on pedunculopontine tegmental neurons in rats: An in vitro studyQ48413773
Double dissociation between the involvement of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in startle increases produced by conditioned versus unconditioned fearQ48579580
Intra-amygdala muscimol decreases operant ethanol self-administration in dependent ratsQ48903690
Investigation of the presence of ghrelin in the central nervous system of the rat and mouseQ48952751
Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear.Q51187428
Expression of the gene encoding the ghrelin receptor in rats selected for differential alcohol preference.Q51886891
GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats.Q52206021
Relationship Between Ghrelin Levels, Alcohol Craving, and Nutritional Status in Current Alcoholic PatientsQ63464437
Increased probability of GABA release during withdrawal from morphineQ71955013
Characterization of the electrophysiological and morphological properties of rat central amygdala neurons in vitroQ73182639
d-Lys-GHRP-6 does not modify the endocrine response to acylated ghrelin or hexarelin in humansQ79368299
The contractile effect of the ghrelin receptor antagonist, D-Lys3-GHRP-6, in rat fundic strips is mediated through 5-HT receptorsQ83187956
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)364-375
P577publication date2012-09-12
P1433published inNeuropsychopharmacologyQ2261280
P1476titleGhrelin increases GABAergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala
P478volume38

Reverse relations

cites work (P2860)
Q47166573Alterations in Rat Accumbens Endocannabinoid and GABA Content during Fentanyl Treatment: The Role of Ghrelin
Q38625183CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats.
Q64986842Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via Mediating Ghrelin and GABAA Receptor Signaling Pathway.
Q47603883Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals
Q35513187Gabaergic control of anxiety-like behavior, but not food intake, induced by ghrelin in the intermediate medial mesopallium of the neonatal chick
Q42323311Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.
Q45988178Ghrelin and nicotine stimulate equally the dopamine release in the rat amygdala.
Q34406857Ghrelin-Derived Peptides: A Link between Appetite/Reward, GH Axis, and Psychiatric Disorders?
Q34250821Intravenous ghrelin administration increases alcohol craving in alcohol-dependent heavy drinkers: a preliminary investigation
Q41813523Kappa opioid receptor-mediated dysregulation of gamma-aminobutyric acidergic transmission in the central amygdala in cocaine addiction
Q34079630Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse
Q52317955Neuroendocrine response to GABA-B receptor agonism in alcohol-dependent individuals: Results from a combined outpatient and human laboratory experiment.
Q64120996On the Abilities of Unconscious Freudian Motivational Drives to Evoke Conscious Emotions
Q90248213On the Nature of the Mother-Infant Tie and Its Interaction With Freudian Drives
Q28109507Role of appetite-regulating peptides in the pathophysiology of addiction: implications for pharmacotherapy
Q88574413The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study

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