MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

scientific article published on 24 February 2016

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.7651
P932PMC publication ID4941323
P698PubMed publication ID26918939
P5875ResearchGate publication ID295860914

P50authorJai PrakashQ40027376
Marie LarssonQ61834764
P2093author name stringGert Storm
Per Sandström
Vegard Tjomsland
Arne Östman
Linda Bojmar
Praneeth R Kuninty
P2860cites workThe pancreatic stellate cell: a star on the rise in pancreatic diseasesQ24676727
The pancreas cancer microenvironmentQ27026705
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The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidationQ28590693
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MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.Q33575825
Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo ChemoradiationQ33620104
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinomaQ33896442
Role of pancreatic stellate cells in pancreatic cancer metastasis.Q34254595
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survivalQ34269713
TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease.Q34429906
Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.Q34475071
miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1Q34607960
Pilot clinical trial of hedgehog pathway inhibitor GDC-0449 (vismodegib) in combination with gemcitabine in patients with metastatic pancreatic adenocarcinomaQ34623264
Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.Q34989886
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapyQ35039281
Rho kinase inhibitors block activation of pancreatic stellate cellsQ35045926
Contribution of microRNAs in understanding the pancreatic tumor microenvironment involving cancer associated stellate and fibroblast cellsQ35666501
Pathophysiological role of microRNA-29 in pancreatic cancer stromaQ35765000
PI3 K/Akt/mTOR-mediated translational control regulates proliferation and differentiation of lineage-restricted RoSH stem cell linesQ36098154
Pancreatic stellate cells: a starring role in normal and diseased pancreasQ36192959
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasisQ36327483
Pancreatic cancer stroma: friend or foe?Q36767415
BMP2 inhibits TGF-β-induced pancreatic stellate cell activation and extracellular matrix formationQ36837670
Cancer-associated stromal fibroblasts promote pancreatic tumor progressionQ36844475
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancerQ36938409
A starring role for stellate cells in the pancreatic cancer microenvironmentQ37059888
Pten in stromal fibroblasts suppresses mammary epithelial tumoursQ37399478
Nuclear translocation of FGFR1 and FGF2 in pancreatic stellate cells facilitates pancreatic cancer cell invasionQ37710812
mTOR and the differentiation of mesenchymal stem cells.Q37885070
Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cellsQ37982808
Molecular pathways: microRNAs as cancer therapeutics.Q38019896
Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironmentQ38204745
The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisalQ38310416
Stromal biology and therapy in pancreatic cancer: a changing paradigmQ38494338
miR-210 regulates the interaction between pancreatic cancer cells and stellate cellsQ39129405
ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growthQ39162935
Targeting miR-21 for the therapy of pancreatic cancerQ39182251
Interleukin 1α sustains the expression of inflammatory factors in human pancreatic cancer microenvironment by targeting cancer-associated fibroblastsQ39489370
PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis.Q39526531
Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancerQ39550421
Pancreatic stellate cells: partners in crime with pancreatic cancer cellsQ39996299
Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cellsQ40515728
PTEN, here, there, everywhereQ42911804
Changes in miR-143 and miR-21 expression and clinicopathological correlations in pancreatic cancers.Q43492600
Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cellsQ44174274
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastomaQ46158804
Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancerQ46453398
Differential and synergistic effects of platelet-derived growth factor-BB and transforming growth factor-beta1 on activated pancreatic stellate cellsQ46604968
Identification, culture, and characterization of pancreatic stellate cells in rats and humansQ47787139
Long-term exposure of human gingival fibroblasts to cigarette smoke condensate reduces cell growth by modulating Bax, caspase-3 and p53 expression.Q51417430
Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.Q52567811
Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.Q53360026
Alteration of the microRNA expression profile during the activation of pancreatic stellate cells.Q54228467
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomasQ57591220
p53 triggers apoptosis in oncogene-expressing fibroblasts by the induction of Noxa and mitochondrial Bax translocationQ63408383
P4510describes a project that usesImageJQ1659584
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
P304page(s)16396-16408
P577publication date2016-02-24
P1433published inOncotargetQ1573155
P1476titleMicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor
P478volume7

Reverse relations

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