Role of the Small GTPase Rho in Modulation of the Inwardly Rectifying Potassium Channel Kir2.1

scientific article published on October 1, 2003

Role of the Small GTPase Rho in Modulation of the Inwardly Rectifying Potassium Channel Kir2.1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/MOL.64.4.987
P953full work available at URLhttps://syndication.highwire.org/content/doi/10.1124/mol.64.4.987
P698PubMed publication ID14500755
P5875ResearchGate publication ID9087625

P2093author name stringS. V Penelope Jones
P2860cites workJournal of PhysiologyQ7743612
Molecular PharmacologyQ1943386
American Journal of PhysiologyQ2160146
Kir2.1 inward rectifier K+ channels are regulated independently by protein kinases and ATP hydrolysisQ38301665
Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxalQ40662491
Potent activation of RhoA by Galpha q and Gq-coupled receptors.Q40730965
Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation.Q40988684
The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin.Q41108830
Regulation of receptor-mediated endocytosis by Rho and Rac.Q41185352
G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathwaysQ41216039
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by GbetagammaQ42544747
Different subtypes of alpha1-adrenoceptor modulate different K+ currents via different signaling pathways in canine ventricular myocytesQ43721275
Regulation of IRK3 Inward RectifierK + Channel by m1 Acetylcholine Receptorand Intracellular MagnesiumQ44040479
Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactionsQ48906142
Dual modulation of an inwardly rectifying potassium conductanceQ48963386
Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation.Q52540033
Alpha 1-adrenoceptors reduce background K+ current in rabbit ventricular myocytesQ68280473
Acetylcholine reduces inward rectification on thymus-derived macrophage cells in cultureQ69017114
Protein kinase C-mediated inhibition of an inward rectifier potassium channel by substance P in nucleus basalis neuronsQ71692798
Beta-adrenergic modulation of glial inwardly rectifying potassium channelsQ72632401
Distinct specificities of inwardly rectifying K(+) channels for phosphoinositidesQ73263368
Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cellsQ74583836
Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndromeQ24291252
Physical and functional interactions of Galphaq with Rho and its exchange factorsQ24669784
Rho GTPases in cell biologyQ27860969
Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channelQ28215456
Modulation of the inward rectifier potassium channel IRK1 by the Ras signaling pathwayQ28216522
The small GTP-binding protein RhoA regulates a delayed rectifier potassium channelQ28274364
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRFQ28292490
Binding of the inward rectifier K+ channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylationQ28294804
Primary structure and functional expression of a mouse inward rectifier potassium channelQ28297815
The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathwayQ29614258
Guanine nucleotide exchange factors for Rho GTPases: turning on the switchQ29618403
GTP-binding protein Gq mediates muscarinic-receptor-induced inhibition of the inwardly rectifying potassium channel IRK1 (Kir 2.1).Q31882890
Electrophysiological remodeling in hypertrophy and heart failureQ33758963
Signaling to Rho GTPasesQ33783547
The role of Rho in G protein-coupled receptor signal transductionQ33932175
Cellular function and control of volume-regulated anion channelsQ34118500
RhoA is required for cortical retraction and rigidity during mitotic cell roundingQ34171845
Inward rectifiers in the heart: an update on I(K1).Q34198377
Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0.Q34840556
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptorQ36324611
Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channelQ36412292
Endothelin-1 Inhibits Inward Rectifier Potassium Channels and Activates Nonspecific Cation Channels in Cultured Endothelial CellsQ36676067
Receptor stimulation causes slow inhibition of IRK1 inwardly rectifying K+ channels by direct protein kinase A-mediated phosphorylationQ37557106
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
molecular medicineQ3523816
P304page(s)987-993
P577publication date2003-10-01
P1433published inMolecular PharmacologyQ1943386
P1476titleRole of the Small GTPase Rho in Modulation of the Inwardly Rectifying Potassium Channel Kir2.1
P478volume64

Reverse relations

cites work (P2860)
Q38937713Antihistamines modulate the integrin signaling pathway in h9c2 rat cardiomyocytes: Possible association with cardiotoxicity
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Q24296441Inwardly rectifying potassium channels: their structure, function, and physiological roles
Q36981091Ion channel regulation by Ras, Rho, and Rab small GTPases.
Q40524509Molecular characterization of an inward rectifier channel (IKir) found in avian vestibular hair cells: cloning and expression of pKir2.1.
Q51798809Quantifying RhoA facilitated trafficking of the epithelial Na+ channel toward the plasma membrane with total internal reflection fluorescence-fluorescence recovery after photobleaching.
Q39927654Regulation of Kir2.1 channels by the Rho-GTPase, Rac1
Q40343616Regulation of a family of inwardly rectifying potassium channels (Kir2) by the m1 muscarinic receptor and the small GTPase Rho.
Q30497995Responses of pigeon vestibular hair cells to cholinergic agonists and antagonists
Q49157136Rho kinase activity governs arteriolar myogenic depolarization.
Q46571808Rho-kinase inhibition and electromechanical coupling in rat and guinea-pig ureter smooth muscle: Ca2+-dependent and -independent mechanisms
Q47603839RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia
Q51792249Rock 'n' Rho: regulation of ion channels.
Q36666708SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology
Q27010607Small G proteins in the cardiovascular system: physiological and pathological aspects
Q36542078Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.
Q24651215Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1
Q46666337Up-regulation of the inwardly rectifying K⁺ channel Kir2.1 (KCNJ2) by protein kinase B (PKB/Akt) and PIKfyve

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