Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum

scientific article published on 17 June 2009

Genistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00152.2009
P698PubMed publication ID19535515
P5875ResearchGate publication ID26300508

P50authorKirk L. HamiltonQ123142750
P2093author name stringPin-Chun Chao
P2860cites workGenistein stimulates electrogenic Cl(-) secretion in mouse jejunumQ42466087
Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal glandQ42474620
CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatasesQ42521984
Modulation of Cl- secretion in rat distal colon by genistein, a protein tyrosine kinase inhibitorQ42526540
Activation of CFTR by UCCF-029 and genisteinQ42661045
Methoxsalen stimulates electrogenic Cl- secretion in the mouse jejunumQ42686204
Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanismQ42798090
cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genisteinQ42829058
Cyclic AMP-dependent Cl secretion is regulated by multiple phosphodiesterase subtypes in human colonic epithelial cellsQ43916380
Genistein potentiates the ANP effect on a K(+)-conductance in HEK-293 cellsQ44522576
Activation of CFTR by genistein in human airway epithelial cell linesQ44546807
DCEBIO stimulates Cl- secretion in the mouse jejunumQ46681166
Direct action of genistein on CFTR.Q48954655
Ion transport across the jejunum in normal and cystic fibrosis mice.Q51610572
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.Q53938455
Ion channels in isolated mouse jejunal crypts.Q53957287
Crypts are the site of intestinal fluid and electrolyte secretionQ56972270
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Localization of protein kinases by anchoring proteins: a theme in signal transductionQ28299903
The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cellsQ28506856
NO Inhibits NaCl absorption by rat thick ascending limb through activation of cGMP-stimulated phosphodiesteraseQ32071542
Murine mCLCA6 is an integral apical membrane protein of non-goblet cell enterocytes and co-localizes with the cystic fibrosis transmembrane conductance regulatorQ33320401
Separate Cl- conductances activated by cAMP and Ca2+ in Cl(-)-secreting epithelial cellsQ33654030
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Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.Q35031290
Function of K+ channels in the intestinal epitheliumQ35184179
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Pharmacology of Protein Kinase InhibitorsQ36213534
Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effectsQ36411954
A-kinase anchoring proteins take shapeQ36463252
The where's and when's of kinase anchoringQ36475672
Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.Q36510038
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Overview of PDEs and their regulationQ36739122
Implications of phytoestrogen intake for breast cancerQ36940395
The effects of electrical field stimulation and tetrodotoxin on ion transport by the isolated rabbit ileumQ37033227
Soy, isoflavones, and prostate cancer.Q37318010
Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epitheliumQ40415302
Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cellsQ40591756
The tyrosine kinase inhibitor genistein increases basal cAMP and potentiates forskolin-induced cAMP accumulation in A549 human airway epithelial cellsQ40682887
Role of KCNQ1 in the cell swelling-induced enhancement of the slowly activating delayed rectifier K(+) currentQ40727629
Two mechanisms of genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in murine cell lineQ40886609
Activation of Cl- channel and Na+/K+/2Cl- cotransporter in renal epithelial A6 cells by flavonoids: genistein, daidzein, and apigeninQ40978052
Alternate stimulation of apical CFTR by genistein in epitheliaQ41250130
Genistein and tyrphostin 47 stimulate CFTR-mediated Cl- secretion in T84 cell monolayersQ41264817
CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cellsQ41267381
Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterasesQ42462628
P433issue3
P304page(s)C688-98
P577publication date2009-06-17
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleGenistein stimulates electrogenic Cl- secretion via phosphodiesterase modulation in the mouse jejunum
P478volume297

Reverse relations

cites work (P2860)
Q38987679Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion
Q35063085Effect of genistein on basal jejunal chloride secretion in R117H CF mice is sex and route specific
Q64117760Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease
Q60048841Genistein diet does not modify crypt morphology in the ob/ob mouse jejunum: a comparison of cryostat and clearing techniques
Q37535558Genistein induces increase in fluid pH, Na+ and HCO3(-) concentration, SLC26A6 and SLC4A4 (NBCe1)-B expression in the uteri of ovariectomized rats
Q82534587Genistein stimulates duodenal HCO3− secretion through PI3K pathway in mice
Q35283636Genistein stimulates jejunum chloride secretion via an Akt-mediated pathway in intact female mice
Q37005218Stimulation of murine intestinal secretion by daily genistein injections: gender-dependent differences
Q48202298Transport of valine across the small intestinal epithelium in pigs fed different valine levels and Bacillus subtilis
Q34640115cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium

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