Metformin interaction with insulin-regulated glucose uptake, using the Xenopus laevis oocyte model expressing the mammalian transporter GLUT4.

scientific article published on July 1999

Metformin interaction with insulin-regulated glucose uptake, using the Xenopus laevis oocyte model expressing the mammalian transporter GLUT4. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-2999(99)00413-6
P698PubMed publication ID10448935

P2093author name stringWiernsperger N
Devos P
Detaille D
P2860cites workMammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteinsQ48418596
The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes.Q50761562
Demonstration of defective glucose uptake and storage in erythrocytes from non-insulin dependent diabetic patients and effects of metformin.Q51599300
Prevention of dexamethasone-induced insulin resistance by metforminQ77512497
Molecular cloning and characterization of an insulin-regulatable glucose transporterQ28268399
Qualitative and quantitative comparison of glucose transport activity and glucose transporter concentration in plasma membranes from basal and insulin-stimulated rat adipose cellsQ28769648
Activation of glucose uptake by insulin and insulin-like growth factor I in Xenopus oocytesQ33849980
Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoformsQ34021929
Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetesQ35601498
Complex regulation of simple sugar transport in insulin-responsive cellsQ36160615
Reconstitution of an insulin signaling pathway in Xenopus laevis oocytes: coexpression of a mammalian insulin receptor and three different mammalian hexose transportersQ36717956
Functional expression of mammalian glucose transporters in Xenopus laevis oocytes: evidence for cell-dependent insulin sensitivityQ36761688
Cellular mechanism of action of metforminQ37882736
Expression of cloned genes and translation of messenger RNA in microinjected Xenopus oocytesQ38009536
Hormonal regulation of glucose transporters in muscle cells in cultureQ40892235
Metformin-insulin interactions: from organ to cellQ40927875
From receptor to transporter: insulin signalling to glucose transport.Q41595809
Differential targeting of glucose transporter isoforms heterologously expressed in Xenopus oocytesQ41866053
Potentiating effect of metformin on insulin-induced glucose uptake and glycogen metabolism with Xenopus oocytesQ42452051
Insulin and insulin-like growth factor I (IGF-I) stimulate GLUT4 glucose transporter translocation in Xenopus oocytesQ42822432
Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activationQ42987313
Activation of Glut1 glucose transporter in human erythrocytesQ47774855
Does insulin-induced increase in the amount of plasma membrane GLUTs quantitatively account for insulin-induced increase in glucose uptake?Q47854163
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmetforminQ19484
African clawed frogQ654718
preproinsulinQ7240673
Xenopus laevis oocyteQ107489871
P304page(s)127-136
P577publication date1999-07-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleMetformin interaction with insulin-regulated glucose uptake, using the Xenopus laevis oocyte model expressing the mammalian transporter GLUT4.
P478volume377

Reverse relations

cites work (P2860)
Q51357044Effects of metformin on the expression of GLUT4 in endometrium of obese women with polycystic ovary syndrome.
Q36343489Is non-insulin dependent glucose uptake a therapeutic alternative? Part 1: physiology, mechanisms and role of non insulin-dependent glucose uptake in type 2 diabetes
Q43299787Metformin effects upon blood pressure and glucose metabolism of monossodium glutamate induced-obese spontaneously hypertensive rats
Q24308803Sugar transporters for intercellular exchange and nutrition of pathogens

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