A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice

scientific article published on October 13, 2010

A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBRC.2010.09.111
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0006291X10018218?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0006291X10018218?httpAccept=text/xml
P698PubMed publication ID20920476

P50authorArlan G. RichardsonQ21062344
P2093author name stringArlan Richardson
Rochelle Wei
Qitao Ran
Anson Pierce
Si-Eun Yoo
Dipti Halade
P2860cites workThe co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteinsQ24290709
Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stressQ24792454
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1Q28118304
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complexQ28118708
Adapting proteostasis for disease interventionQ28131818
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotectiveQ28185660
Aggresomes: a cellular response to misfolded proteinsQ28292275
HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in miceQ28588529
Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stressQ28752254
Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock FactorQ29619759
HSF1-controlled and age-associated chaperone capacity in neurons and muscle cells of C. elegans.Q33522212
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperonesQ35799651
Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongationQ35965483
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1Q36194366
Chaperone-mediated autophagy in aging and diseaseQ36510519
Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.Q37474527
Inefficient degradation of truncated polyglutamine proteins by the proteasomeQ37592772
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy.Q40050938
Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse modelsQ40392026
Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing proteinQ40662036
Demyelination, astrogliosis, and accumulation of ubiquitinated proteins, hallmarks of CNS disease in hsf1-deficient mice.Q43645646
Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity.Q45929966
Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genesQ46123618
GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosisQ46426860
Maintenance of olfactory neurogenesis requires HSF1, a major heat shock transcription factor in mice.Q46818311
Analysis of heat shock transcription factor for suppression of polyglutamine toxicityQ48706236
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene.Q52527826
Heat shock factor activation in human muscles following a demanding intermittent exercise protocol is attenuated with hyperthermiaQ80203803
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectanimal disease modelQ64732998
P1104number of pages7
P304page(s)59-65
P577publication date2010-10-13
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleA Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice
P478volume402