DNA damage in cultured skin microvascular endothelial cells exposed to gamma rays and treated by the combination pentoxifylline and alpha-tocopherol

scientific article

DNA damage in cultured skin microvascular endothelial cells exposed to gamma rays and treated by the combination pentoxifylline and alpha-tocopherol is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/09553000600733150
P698PubMed publication ID16782648

P50authorPhilippe VoisinQ128205348
P2093author name stringJean-Pierre Pouget
Carine Laurent
Philippe Voisin
P2860cites workPreferential radiosensitization of G1 checkpoint-deficient cells by methylxanthines.Q54192734
DNA Damage Induced in Cells by γ and UVA Radiation As Measured by HPLC/GC−MS and HPLC−EC and Comet AssayQ56919003
Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stressQ67493487
Pentoxifylline Does Not Spare Acute Radiation Reactions in Rat Lung and SkinQ67719392
The effect of pentoxifylline on early and late radiation injury following fractionated irradiation in C3H miceQ69651914
Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: an experimental studyQ71091183
Radiation injury in rat lung. III. Plasminogen activator and fibrinolytic inhibitor activitiesQ71239134
Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trialQ72748882
An Ultrastructural Study of the Development of Radiation Injury in the LungQ72856069
Effect of pentoxifylline on radiation-induced lung and skin toxicity in ratsQ72895676
Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherolQ73042279
[Late effects of mammary radiotherapy on skin and subcutaneous tissues]Q74617420
Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental studyQ74657341
Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effectsQ28183114
Uterine restoration by radiation sequelae regression with combined pentoxifylline-tocopherol: a phase II studyQ34132776
Normal tissue radiobiology: from the laboratory to the clinic.Q34137824
A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasminQ34375667
ATM as a target for novel radiosensitizersQ34418313
Regulation of cell signalling by vitamin EQ35105487
Protection against ionizing radiation by antioxidant nutrients and phytochemicalsQ35160353
Inhibition of DNA repair by Pentoxifylline and related methylxanthine derivativesQ35576458
Chronic oxidative stress and radiation-induced late normal tissue injury: a reviewQ35809682
Role of pentoxifylline and vitamin E in attenuation of radiation-induced fibrosisQ36035250
The role of DNA double strand breaks in lonizing radiation-induced killing of eukaryotic cellsQ36952860
Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis.Q39515610
Pathophysiology of irradiated skin and breastQ40505499
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitorsQ40511617
Radiosensitization and DNA repair inhibition by pentoxifylline in NIH3T3 p53 transfectantsQ40687005
The effects of pentoxifylline on the survival of human glioma cells with continuous and intermittent stereotactic radiosurgery irradiationQ40702530
D-alpha-tocopheryl succinate (vitamin E) enhances radiation-induced chromosomal damage levels in human cancer cells, but reduces it in normal cellsQ40712374
Chromosomal aberrations, sister chromatid exchanges and micronuclei induced by pentoxifylline in in vitro cultivated Chinese hamster cells (V79) and human blood lymphocytesQ40783355
Frequency of radiation-induced micronuclei in neuronal cells does not correlate with clonogenic survivalQ40906768
Effect of antioxidant vitamin supplementation on DNA damage and repair in human lymphoblastoid cellsQ41139980
Clinical radiation pathology as applied to curative radiotherapyQ41554278
Microvascular and tumor cell alterations during continuous hyperfractionated irradiation: an electron microscopic investigation on the rat R1H rhabdomyosarcomaQ42473994
Ultrastructural studies on tumor capillaries of a rat rhabdomyosarcoma during fractionated radiotherapy.Q42493530
Complete healing of severe osteoradionecrosis with treatment combining pentoxifylline, tocopherol and clodronateQ44010369
Preferential radiosensitization in p53-mutated human tumour cell lines by pentoxifylline-mediated disruption of the G2/M checkpoint controlQ44113601
Modulation of radiation-induced tumour necrosis factor alpha (TNF-alpha) expression in the lung tissue by pentoxifyllineQ44145514
Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis.Q44493462
Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trialQ44707469
Prophylactic effect of pentoxifylline on radiotherapy complications: a clinical studyQ44822415
Pentoxifylline enhances tumor oxygenation and radiosensitivity in rat rhabdomyosarcomas during continuous hyperfractionated irradiationQ44883751
In vitro antioxidant properties of pentoxifylline, piracetam, and vinpocetineQ45711598
The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifyllineQ46242261
Abrogation of G(2)/M-phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin in TP53 mutant human tumor cellsQ46403915
Modulation of DNA damage by pentoxifylline and alpha-tocopherol in skin fibroblasts exposed to Gamma raysQ46556541
P433issue5
P921main subjectendotheliumQ111140
pentoxifyllineQ416331
DNA damageQ5205747
P304page(s)309-321
P577publication date2006-05-01
P1433published inInternational Journal of Radiation BiologyQ2093427
P1476titleDNA damage in cultured skin microvascular endothelial cells exposed to gamma rays and treated by the combination pentoxifylline and alpha-tocopherol
P478volume82

Reverse relations

cites work (P2860)
Q37038170Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells
Q90638439Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage
Q43166759DNA damage and repair after exposure to sevoflurane in vivo, evaluated in Swiss albino mice by the alkaline comet assay and micronucleus test.
Q35078543Dramatic increase in oxidative stress in carbon-irradiated normal human skin fibroblasts
Q42274604Mitochondrial ROS and radiation induced transformation in mouse embryonic fibroblasts
Q37392186Prevention of future incidents and investigational lines
Q36082645Studies of the in vivo radiosensitivity of human skin fibroblasts.
Q36480184The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells
Q90192485The Possibility of Using Genotoxicity, Oxidative Stress and Inflammation Blood Biomarkers to Predict the Occurrence of Late Cutaneous Side Effects after Radiotherapy
Q37044976The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetes

Search more.