scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M103139200 |
P698 | PubMed publication ID | 11522777 |
P2093 | author name string | F G Giancotti | |
M De Luca | |||
E Dellambra | |||
G Zambruno | |||
O Golisano | |||
S Cicuzza | |||
A L Salvati | |||
S Bondanza | |||
S Prislei | |||
A Orecchia | |||
E Siviero | |||
M L Madeddu | |||
P2860 | cites work | A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia | Q24310172 |
Herlitz's junctional epidermolysis bullosa is linked to mutations in the gene (LAMC2) for the gamma 2 subunit of nicein/kalinin (LAMININ-5) | Q24312169 | ||
Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa | Q24319905 | ||
The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation | Q24532185 | ||
The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome | Q24548194 | ||
Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding | Q24670751 | ||
Laminin 5 binds the NC-1 domain of type VII collagen | Q24676762 | ||
Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180 | Q24682604 | ||
Integrin beta 4 mutations associated with junctional epidermolysis bullosa with pyloric atresia | Q28118736 | ||
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180 | Q28211758 | ||
A Homozygous Nonsense Mutation in the β3 Chain Gene of Laminin 5 (LAMB3) in Herlitz Junctional Epidermolysis Bullosa | Q28298888 | ||
Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival | Q28592841 | ||
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells | Q29614425 | ||
Signal transduction by lymphocyte antigen receptors | Q29619894 | ||
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes | Q31485514 | ||
Structure and function of hemidesmosomes: more than simple adhesion complexes | Q33592752 | ||
Crossroads on cytoskeletal highways | Q33734286 | ||
Polarized integrin mediates human keratinocyte adhesion to basal lamina | Q33777898 | ||
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes | Q33899956 | ||
Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. | Q36256645 | ||
Proteolytic processing of endogenous and recombinant beta 4 integrin subunit | Q36531714 | ||
Clonal analysis of stably transduced human epidermal stem cells in culture | Q37339157 | ||
The beta 4 subunit cytoplasmic domain mediates the interaction of alpha 6 beta 4 integrin with the cytoskeleton of hemidesmosomes | Q40241664 | ||
Downregulation of 14-3-3sigma prevents clonal evolution and leads to immortalization of primary human keratinocytes | Q40876917 | ||
Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosa | Q40951954 | ||
Laminins: a family of diverse multifunctional molecules of basement membranes | Q40970625 | ||
Linking integrin alpha6beta4-based cell adhesion to the intermediate filament cytoskeleton: direct interaction between the beta4 subunit and plectin at multiple molecular sites. | Q41043907 | ||
Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. | Q41762995 | ||
Polarized expression of integrin receptors (alpha 6 beta 4, alpha 2 beta 1, alpha 3 beta 1, and alpha v beta 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytes | Q42470291 | ||
The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. | Q42478449 | ||
Distinctive integrin expression in the newly forming epidermis during wound healing in humans | Q42509086 | ||
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice | Q42519143 | ||
Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing. | Q42771319 | ||
Expression of high molecular weight (67K) keratin in human keratinocytes cultured on dead de-epidermized dermis | Q47207617 | ||
Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa. | Q47895646 | ||
Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice. | Q52200996 | ||
P433 | issue | 44 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | junctional epidermolysis bullosa | Q3726862 |
P304 | page(s) | 41336-41342 | |
P577 | publication date | 2001-08-24 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Gene correction of integrin beta4-dependent pyloric atresia-junctional epidermolysis bullosa keratinocytes establishes a role for beta4 tyrosines 1422 and 1440 in hemidesmosome assembly | |
P478 | volume | 276 |
Q34069632 | Bone marrow transplantation restores epidermal basement membrane protein expression and rescues epidermolysis bullosa model mice |
Q36425931 | Gene therapy in combination with tissue engineering to treat epidermolysis bullosa. |
Q36039723 | Progress and prospects of skin gene therapy: a ten year history |
Q45870379 | Safe selection of genetically manipulated human primary keratinocytes with very high growth potential using CD24. |
Q45862956 | Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer |
Q35056805 | Type XVII collagen gene mutations in junctional epidermolysis bullosa and prospects for gene therapy |
Q81591731 | [Gene therapy and the skin] |
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