Single nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity

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Single nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11427-012-4365-0
P698PubMed publication ID22932886
P5875ResearchGate publication ID230762704

P2093author name stringLiang Wu
Cheng Zhu
Yue Li
HongMei Wang
HaiYan Lin
JingHui Lei
XiaoGuang Yu
P2860cites workControl of pancreas and liver gene expression by HNF transcription factorsQ24618003
DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and ActivityQ27654868
The glucocorticoid receptor is essential for maintaining basal and dexamethasone-induced repression of the murine corticosteroid-binding globulin geneQ28373526
HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitroQ28508478
Regulation of the rat UGT1A6 by glucocorticoids involves a cryptic glucocorticoid response elementQ28570810
Decreased expression levels of rat liver glutathione S-transferase A2 and albumin during the acute phase response are mediated by HNF1 (hepatic nuclear factor 1) and IL6DEX-NPQ28572668
Corticosteroid-binding globulin status at the fetomaternal interface during human term pregnancyQ32023653
Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promotersQ33660554
A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1betaQ33873845
Hormone binding globulins undergo serpin conformational change in inflammationQ34167746
Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptorQ34178695
CBG Santiago: a novel CBG mutationQ34225739
Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasmaQ34281171
A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol.Q34308259
Organization of the human corticosteroid binding globulin gene and analysis of its 5'-flanking regionQ34480990
Plasma binding proteins as mediators of corticosteroid action in vertebratesQ34962816
Molecular and structural basis of steroid hormone binding and release from corticosteroid-binding globulinQ37566701
Molecular properties of corticosteroid binding globulin and the sex-steroid binding proteinsQ37909539
cis-regulatory elements within the proximal promoter of the rat gene encoding corticosteroid-binding globulin.Q38291628
Role of the liver-enriched transcription factor HNF-1 alpha in expression of the CYP2E1 geneQ38297073
Proximal HNF1 element is essential for the induction of human UDP-glucuronosyltransferase 1A1 by glucocorticoid receptorQ38317608
Hepatic nuclear proteins that bind cis-regulatory elements in the proximal promoter of the rat corticosteroid-binding globulin geneQ38348487
Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/betaQ40047043
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domainQ42642911
Novel corticosteroid-binding globulin variant that lacks steroid binding activityQ42976964
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoterQ44517600
Glucocorticoid receptor-mediated upregulation of human CYP27A1, a potential anti-atherogenic enzymeQ44886116
Residues in the human corticosteroid-binding globulin reactive center loop that influence steroid binding before and after elastase cleavageQ45163059
Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in nucleoli.Q46631962
Potential functions of plasma steroid-binding proteins.Q47875088
Hepatocyte nuclear factor-4 controls transcription from a TATA-less human sex hormone-binding globulin gene promoter.Q48001583
High frequency of SERPINA6 polymorphisms that reduce plasma corticosteroid-binding globulin activity in Chinese subjects.Q51760904
P433issue8
P921main subjectsingle-nucleotide polymorphismQ501128
P304page(s)699-708
P577publication date2012-08-30
P1433published inScience in China. Series C: Life SciencesQ2619480
P1476titleSingle nucleotide polymorphisms in the human corticosteroid-binding globulin promoter alter transcriptional activity
P478volume55

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Q34380321Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβcites workP2860

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