Disparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: inhibition of basal apoptosis by diclofenac

scientific article

Disparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: inhibition of basal apoptosis by diclofenac is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/SJ.BJP.0704497
P932PMC publication ID1573157
P698PubMed publication ID11815376
P5875ResearchGate publication ID11544952

P2093author name stringMiranda Ashton
Peter J Hanson
P2860cites workNonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysisQ24646764
Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugsQ24670111
Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cellsQ28377535
Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cellsQ33179554
Death by design: mechanism and control of apoptosisQ33803998
Ceramide in the eukaryotic stress responseQ33826715
Nonsteroidal anti-inflammatory drugs (NSAIDs), cyclooxygenases, and the cell cycle. Their interactions in colon cancer.Q33858237
Colorectal cancer prevention and treatmentQ33951479
Nonsteroidal anti-inflammatory drug gastropathyQ33993897
Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblastsQ34020051
Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosisQ34307869
Clinical pharmacokinetics of ibuprofen. The first 30 yearsQ34461383
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosisQ35742409
Chemical gastritis and Helicobacter pylori related gastritis in patients receiving non-steroidal anti-inflammatory drugs: comparison and correlation with peptic ulcerationQ37116086
Protein binding as a primary determinant of the clinical pharmacokinetic properties of non-steroidal anti-inflammatory drugsQ39662377
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesionsQ40722651
Apoptosis induction and cyclooxygenase-2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase-2-selective non-steroidal anti-inflammatory drug NS-398.Q40882258
Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred yearsQ41354684
Cell death induction by TNF: a matter of self controlQ41468884
Clinical pharmacokinetics of diclofenac. Therapeutic insights and pitfallsQ41603966
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.Q41972615
Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-mycQ42205510
Opposite effects of flurbiprofen and the nitroxybutyl ester of flurbiprofen on apoptosis in cultured guinea-pig gastric mucous cellsQ42489515
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugsQ42551374
COX-1 and COX-2 products in the gut: therapeutic impact of COX-2 inhibitorsQ43086302
Isolated guinea pig gastric chief cells express tumour necrosis factor receptors coupled with the sphingomyelin pathwayQ43226057
Helicobacter pylori-dependent ceramide production may mediate increased interleukin 8 expression in human gastric cancer cell linesQ45126674
Guinea pig gastric mucosal cells produce abundant superoxide anion through an NADPH oxidase-like systemQ46371235
Spontaneous apoptotic DNA fragmentation in cultured guinea pig gastric mucosal cellsQ46689619
Reduced glutathione modulates Ca(2+)-mediated damage to rabbit isolated gastric mucosal cells.Q50771039
Adaptation of the bicinchoninic acid protein assay for use with microtiter plates and sucrose gradient fractionsQ69504812
Role of tumor necrosis factor alpha release and leukocyte margination in indomethacin-induced gastric injury in ratsQ71670787
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrestQ72095851
Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenacQ74459678
Induction of heat shock protein 72 by a nitric oxide donor in guinea-pig gastric mucosal cellsQ77164480
Nonsteroidal antiinflammatory drugs could reverse Helicobacter pylori-induced apoptosis and proliferation in gastric epithelial cellsQ77348985
Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in ratsQ77374986
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
apoptotic processQ14599311
DiclofenacQ244408
P304page(s)407-416
P577publication date2002-01-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleDisparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: inhibition of basal apoptosis by diclofenac
P478volume135

Reverse relations

cites work (P2860)
Q387339252-Ethoxybenzamide stimulates melanin synthesis in B16F1 melanoma cells via the CREB signaling pathway.
Q46305650A collagen IV matrix is required for guinea pig gastric epithelial cell monolayers to provide an optimal model of the stomach surface for biopharmaceutical screening
Q46671599Apoptosis induction in gastric mucous cells in vitro: lesser potency of Helicobacter pylori than Escherichia coli lipopolysaccharide, but positive interaction with ibuprofen
Q40133487Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution
Q44643367Diclofenac induces apoptosis in hepatocytes
Q38809428Dual effects of acetylsalicylic acid on ERK signaling and Mitf transcription lead to inhibition of melanogenesis.
Q39726376Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP.
Q39332507Expression of pleiotrophin, an important regulator of cell migration, is inhibited in intestinal epithelial cells by treatment with non-steroidal anti-inflammatory drugs
Q38586382In the Huh7 Hepatoma Cells Diclofenac and Indomethacin Activate Differently the Unfolded Protein Response and Induce ER Stress Apoptosis
Q47579301Indomethacin inhibits melanogenesis via down-regulation of Mitf mRNA transcription
Q36307625Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration by disrupting calpain signaling
Q46788827Intracellular effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells in culture
Q39835752Non-steroidal anti-inflammatory drugs inhibit calpain activity and membrane localization of calpain 2 protease
Q42471534Paracellular permeability is increased by basal lipopolysaccharide in a primary culture of colonic epithelial cells; an effect prevented by an activator of Toll-like receptor-2.
Q28190341Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture
Q36483712Repurposing Drugs in Oncology (ReDO)-diclofenac as an anti-cancer agent
Q38710551Suppression of calpain expression by NSAIDs is associated with inhibition of cell migration in rat duodenum

Search more.