Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies

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Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CNCR.10915
P698PubMed publication ID12404285
P5875ResearchGate publication ID11060285

P50authorLucio CatalanoQ88806906
Jaroslaw P. MaciejewskiQ89912865
Patrizia RicciQ91336536
Carmine SelleriQ111968238
Bruno RotoliQ114094956
Claudia AndrettaQ114094999
Luigiana LucianoQ114576228
P2860cites workDeletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasiaQ28266438
Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: clinical and pathophysiological featuresQ31893453
Apoptosis and its significance in MDS: controversies revisitedQ33727681
A hypothesis for the pathogenesis of myelodysplastic syndromes: implications for new therapies.Q33818649
Myelodysplastic syndrome and aplastic anemia: distinct entities or diseases linked by a common pathophysiology?Q33838981
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The molecular basis of T helper 1 and T helper 2 cell differentiationQ34106569
Excessive apoptosis in low risk myelodysplastic syndromes (MDS).Q34293505
The role of apoptosis in the pathogenesis of the myelodysplastic syndromesQ34336402
Evolving concepts in myelodysplastic syndromes.Q34434236
The pathophysiology of acquired aplastic anemiaQ34739892
Limited heterogeneity of T cell receptor BV usage in aplastic anemiaQ36167878
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.Q40606547
Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromesQ40806143
Proliferation and differentiation of myelodysplastic CD34+ cellsQ41047214
Downregulation of Fas ligand by sheddingQ41071790
Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemiaQ41670643
Fas ligand mediates activation-induced cell death in human T lymphocytesQ42942730
Successful treatment with cyclosporin A for myelodysplastic syndrome with erythroid hypoplasia associated with T-cell receptor gene rearrangementsQ43724324
Intracellular Fas ligand is elevated in T lymphocytes in severe aplastic anaemiaQ43742783
Increased cytotoxic T cells with effector phenotype in aplastic anemia and myelodysplasiaQ43791974
Expression of tumor necrosis factor-related apoptosis-inducing ligand, Apo2L, and its receptors in myelodysplastic syndrome: effects on in vitro hemopoiesisQ43792141
Immunosuppressive therapy for patients with refractory anemiaQ43834373
Infliximab chimaeric anti-tumour necrosis factor alpha monoclonal antibody treatment for patients with myelodysplastic syndromesQ43883722
The clinical and biological effects of thalidomide in patients with myelodysplastic syndromes.Q43885598
In vitro proliferation and differentiation of erythroid progenitors from patients with myelodysplastic syndromes: evidence for Fas-dependent apoptosis.Q43893064
Hypocellular myelodysplastic syndromes (MDS): new proposals.Q51043728
Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes.Q52528893
Activation-induced cell death in murine T cell hybridomas. Differential regulation of Fas (CD95) versus Fas ligand expression by cyclosporin A and FK506.Q54341335
Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapyQ58481923
Immunosuppressive therapy for hypoplastic myelodysplastic syndromeQ73265771
Absolute number of circulating CD34+ cells is abnormally low in refractory anemias and extremely high in RAEB and RAEB-t; novel pathologic features of myelodysplastic syndromes identified by highly sensitive flow cytometryQ73400379
Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndromeQ73640523
Antithymocyte globulin for patients with myelodysplastic syndromeQ73945799
Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrowQ74263466
Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasiaQ74476173
Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation in vitroQ74592984
Successful establishment of long-term bone marrow cultures in 103 patients with myelodysplastic syndromesQ74613747
Long-term bone marrow culture profiles in patients with myelodysplastic syndromes are not explicable by defective apoptosisQ74813026
Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndromeQ77066416
Oligoclonal T cell expansion in myelodysplastic syndrome: evidence for an autoimmune processQ77087569
Fas/APO-1 (CD95) expression in myelodysplastic syndromesQ77132466
Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profilesQ77348195
Biologic characteristics of patients with hypocellular myelodysplastic syndromesQ77403214
A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndromeQ77476802
Evidence for involvement of tumor necrosis factor-alpha in apoptotic death of bone marrow cells in myelodysplastic syndromesQ77779024
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcyclosporineQ367700
P304page(s)1911-1922
P577publication date2002-11-01
P1433published inCancerQ326041
P1476titleEffects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies
P478volume95

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cites work (P2860)
Q58041641Activated T-lymphocytes with myelosuppressive properties in patients with chronic idiopathic neutropenia
Q52717549Aging- and Senescence-associated Changes of Mesenchymal Stromal Cells in Myelodysplastic Syndromes.
Q26739239Bone Marrow Immunity and Myelodysplasia
Q38060835Emerging immunosuppressive drugs in myelodysplastic syndromes.
Q35567932Immune dysregulation in myelodysplastic syndrome
Q37724605Immunological derangement in hypocellular myelodysplastic syndromes
Q26864200Immunomodulatory treatment of myelodysplastic syndromes: antithymocyte globulin, cyclosporine, and alemtuzumab
Q35848761Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors.
Q42541218Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment
Q35848521Interferon-gamma-induced gene expression in CD34 cells: identification of pathologic cytokine-specific signature profiles
Q35001132Myelodysplastic syndrome and histone deacetylase inhibitors: "to be or not to be acetylated"?
Q53632729Myelodysplastic syndrome.
Q35855632Response to cyclosporine therapy in patients with myelodysplastic syndrome: a clinical study of 12 cases and literature review
Q37864686Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: implications for immunotherapy
Q38348119The inflammatory microenvironment in MDS.
Q53242640Treatment of myelodysplastic syndrome with cyclosporin A.

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