Complement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent manner

scientific article published on September 2005

Complement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent manner is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.73.9.6138-6142.2005
P932PMC publication ID1231105
P698PubMed publication ID16113335

P2093author name stringRodolfo C Garcia
Marina Cinco
Rossella Murgia
P2860cites workAnalysis of antibody response to the outer surface protein family in lyme borreliosis patientsQ77563693
The continuing saga of complement receptor type 3 (CR3)Q24562088
Early and late antibody responses to full-length and truncated constructs of outer surface protein A of Borrelia burgdorferi in Lyme diseaseQ24682570
The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells.Q33602800
An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.Q33606863
Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory propertiesQ33608211
Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi , to integrin α v β 3Q34197056
A monoclonal antibody to OspA inhibits association of Borrelia burgdorferi with human endothelial cellsQ34523034
Analysis of the sugar specificity and molecular location of the beta-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18).Q34732196
Immune evasion of Borrelia burgdorferi: insufficient killing of the pathogens by complement and antibodyQ34761880
Cell adhesion receptors - signaling capacity and exploitation by bacterial pathogensQ34985802
Interaction of Lyme disease spirochetes with cultured eucaryotic cellsQ35094799
Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirocheteQ35163595
Characterization of outer membranes isolated from Borrelia burgdorferi, the Lyme disease spirocheteQ35415911
Borrelia burgdorferi upregulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitroQ35450776
Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surfaceQ35577517
Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme borreliosis. Complexity of humoral and cellular immune responsesQ35822563
ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)Q36224191
The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritisQ36364212
Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme diseaseQ36366179
Essential role for OspA/B in the life cycle of the Lyme disease spirocheteQ36403858
Attachment of Borrelia burgdorferi within Ixodes scapularis mediated by outer surface protein AQ37242456
Elastase is the only human neutrophil granule protein that alone is responsible for in vitro killing of Borrelia burgdorferiQ39570583
Arthropod- and host-specific gene expression by Borrelia burgdorferiQ39777362
Integrin CR3 mediates the binding of nonspecifically opsonized Borrelia burgdorferi to human phagocytes and mammalian cellsQ39831531
Accelerated decay of C3b to iC3b when C3b is bound to the Cryptococcus neoformans capsuleQ40269086
Variable small protein (Vsp)-dependent and Vsp-independent pathways for glycosaminoglycan recognition by relapsing fever spirochaetes.Q40620448
Borrelia burgdorferi are susceptible to killing by a variety of human polymorphonuclear leukocyte componentsQ43937792
Fcgamma-receptors induce Mac-1 (CD11b/CD18) mobilization and accumulation in the phagocytic cup for optimal phagocytosisQ44564211
Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritisQ47762137
Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31.Q47988454
The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi.Q48032295
Detection of glycoproteins in Borrelia burgdorferiQ59344937
Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell bindingQ73042813
Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferiQ73065110
Interaction with Borrelia burgdorferi causes increased expression of the CR3 integrin and increased binding affinity to fibronectin via CR3Q73183832
Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophilsQ73326096
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectBorrelia burgdorferiQ2723634
P304page(s)6138-6142
P577publication date2005-09-01
P1433published inInfection and ImmunityQ6029193
P1476titleComplement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent manner
P478volume73

Reverse relations

cites work (P2860)
Q102152189A combined transcriptomic approach to identify candidates for an anti-tick vaccine blocking B. afzelii transmission
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Q38981732Actin-Dependent Regulation of Borrelia burgdorferi Phagocytosis by Macrophages
Q28257106CD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferi
Q30500392Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis
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Q38234946The Cross-Talk between Spirochetal Lipoproteins and Immunity
Q30539638The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages

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