Expression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo.

scientific article published on 20 November 2015

Expression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3324/HAEMATOL.2015.136754
P932PMC publication ID4815733
P698PubMed publication ID26589910
P5875ResearchGate publication ID284277706

P50authorCaroline PernerQ61479434
P2093author name stringThomas Fischer
Florian H Heidel
Tina M Schnöder
Denise Wolleschak
Caroline Ebert
P2860cites workJakpot! New small molecules in autoimmune and inflammatory diseasesQ27001957
Intracellular retention of ABL kinase inhibitors determines commitment to apoptosis in CML cellsQ28481327
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosisQ33391880
Ruxolitinib versus standard therapy for the treatment of polycythemia vera.Q33420037
ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development.Q38107993
Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib.Q38150978
Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevanceQ38243832
P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.Q39130447
JAK Inhibition Impairs NK Cell Function in Myeloproliferative NeoplasmsQ41127061
JAK1/2 inhibition impairs T cell function in vitro and in patients with myeloproliferative neoplasmsQ41138516
Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.Q54254821
Ruxolitinib is a potent immunosuppressive compound: is it time for anti-infective prophylaxis?Q54393708
MDR1 expression predicts outcome of Ph+ chronic phase CML patients on second-line nilotinib therapy after imatinib failureQ58023697
Development of imatinib and dasatinib resistance: dynamics of expression of drug transportersABCB1, ABCC1, ABCG2, MVP, and SLC22A1Q60447894
Activity of therapeutic JAK 1/2 blockade in graft-versus-host diseaseQ87635679
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectruxolitinibQ7383611
P304page(s)e81-5
P577publication date2015-11-20
P1433published inHaematologicaQ5638209
P1476titleExpression and function of ABC-transporter protein ABCB1 correlates with inhibitory capacity of Ruxolitinib in vitro and in vivo
P478volume101

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