scholarly article | Q13442814 |
P2093 | author name string | Shah MA | |
Neal MJ | |||
P2860 | cites work | The action of gamma-vinyl-GABA and gamma-acetylenic-GABA on the resting and stimulated release of GABA in vivo | Q71207668 |
gamma-Aminobutyric acid metabolism in rat brain following chronic oral administration of ethanolamine O-sulphate | Q71259408 | ||
Increased gamma-aminobutyric acid (GABA), homocarnosine and beta-alanine in cerebrospinal fluid of patients treated with gamma-vinyl GABA (4-amino-hex-5-enoic acid) | Q71559140 | ||
Anticonvulsant and biochemical effects of inhibitors of GABA aminotransferase and valproic acid during subchronic treatment in mice | Q71604447 | ||
The distribution of glutamic-gamma-aminobutric transaminase in the nervous system of the rhesus monkey | Q78655205 | ||
4-amino-hex-5-enoic acid, a selective catalytic inhibitor of 4-aminobutyric-acid aminotransferase in mammalian brain | Q28331377 | ||
Double-blind study of gamma-vinyl GABA in patients with refractory epilepsy | Q34054805 | ||
Efficacy and safety of vigabatrin in the long-term treatment of refractory epilepsy | Q34396923 | ||
Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, ?-acetylenic GABA (4-amino-hex-5-ynoic acid) and ?-vinyl GABA (4-amino-hex-5-enoic acid) | Q39625389 | ||
On the mechanism by which veratridine causes a calcium-independent release of gamma-aminobutyric acid from brain slices | Q39929449 | ||
Effect of electrical stimulation and high potassium concentrations on the effux of (14C) glycine from slices of spinal cord | Q40017837 | ||
Baclofen and phaclofen modulate GABA release from slices of rat cerebral cortex and spinal cord but not from retina | Q42847554 | ||
Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons | Q48106989 | ||
One to three day dose intervals during subchronic treatment of epileptic gerbils with gamma-vinyl GABA: anticonvulsant efficacy and alterations in regional brain GABA levels | Q48182897 | ||
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils | Q48362163 | ||
Stimulated release of endogenous GABA and glycine from the goldfish retina | Q48445018 | ||
Substantia nigra: site of anticonvulsant activity mediated by gamma-aminobutyric acid | Q48858993 | ||
Subcellular distribution of endogenous and (3H) gamma-aminobutyric acid in rat cerebral cortex | Q48987498 | ||
The fluorometric measurement of glutamic decarboxylase and its distribution in brain. | Q51318976 | ||
Immunocytochemical evidence that vigabatrin in rats causes GABA accumulation in glial cells of the retina | Q69592066 | ||
Effects of anticonvulsants on the in vivo and in vitro release of GABA | Q70719551 | ||
Biochemical and clinical effects of gamma-vinyl GABA in patients with epilepsy | Q70789166 | ||
Gamma-vinyl-GABA: a single-blind trial in patients with epilepsy | Q71018771 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 324-328 | |
P577 | publication date | 1990-06-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Development of tolerance to the effects of vigabatrin (gamma-vinyl-GABA) on GABA release from rat cerebral cortex, spinal cord and retina | |
P478 | volume | 100 |
Q57098730 | Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism |
Q54231363 | Adjuvant vigabatrin in refractory epilepsy: a ceiling to effective dosage in individual patients? |
Q33982061 | Characteristic retinal atrophy with secondary "inverse" optic atrophy identifies vigabatrin toxicity in children |
Q28378109 | Characteristics of a unique visual field defect attributed to vigabatrin |
Q28564804 | Detection of reduced GABA synthesis following inhibition of GABA transaminase using in vivo magnetic resonance signal of [13C]GABA C1 |
Q41772520 | Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats |
Q48158635 | Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid, and valproate on levels of various amino acids in rat brain regions and plasma |
Q44009053 | Effects of gamma-vinyl GABA (vigabatrin) on blood pressure and body weight of hypertensive and normotensive rats |
Q48340498 | Effects of increased gamma-aminobutyric acid levels on GAD67 protein and mRNA levels in rat cerebral cortex |
Q41891059 | Effects of single and multiple increasing doses of vigabatrin on brain gaba metabolism and correlation with vigabatrin plasma concentration |
Q32027616 | Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics |
Q42713628 | Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits |
Q35590459 | Epilepsy patients treated with vigabatrin exhibit reduced ocular blood flow |
Q34559174 | Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs |
Q41649696 | GABA(A) receptors mediate inhibition of T cell responses. |
Q43183029 | Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy |
Q30768157 | In vivo monitoring of rat brain metabolites during vigabatrin treatment using localized 2D-COSY. |
Q43463173 | Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex |
Q41767611 | Longitudinal changes in photopic OPs occurring with vigabatrin treatment |
Q32066867 | Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin |
Q34928181 | Neurotoxic effects of GABA-transaminase inhibitors in the treatment of epilepsy: ocular perfusion and visual performance |
Q36747283 | Nuclear magnetic resonance detection of increased cortical GABA in vigabatrin-treated rats in vivo. |
Q41514405 | Optimizing the indication of vigabatrin in children with refractory epilepsy |
Q36586336 | Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin |
Q99634865 | Proteomics Reveals the Potential Protective Mechanism of Hydrogen Sulfide on Retinal Ganglion Cells in an Ischemia/Reperfusion Injury Animal Model |
Q90319435 | Rational approaches for the design of various GABA modulators and their clinical progression |
Q43958757 | Retinal neurochemical changes following application of glutamate as a metablolic substrate |
Q48144592 | Role of nitric oxide on GABA, glutamic acid, activities of GABA-T and GAD in rat brain cerebral cortex |
Q37149913 | Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity |
Q44285965 | The effects of GABA and vigabatrin on horizontal cell responses to light and the effect of vigabatrin on the electroretinogram |
Q48925359 | The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). |
Q43686221 | Vigabatrin effect on inner retinal function |
Q43774639 | Vigabatrin protects against hippocampal damage but is not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy |
Q61848313 | Vigabatrin reduces epileptiform activity in brain slices from pharmacoresistant epilepsy patients |
Q44489274 | Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina |
Q36676442 | Vigabatrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy and disorders of motor control |
Q35454439 | Visual field defects associated with vigabatrin therapy |
Q34313490 | Visual field defects with vigabatrin: epidemiology and therapeutic implications |
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