Reduced microtubule acetylation in cystic fibrosis epithelial cells

scientific article published on 19 July 2013

Reduced microtubule acetylation in cystic fibrosis epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPLUNG.00411.2012
P932PMC publication ID3763039
P698PubMed publication ID23873844
P5875ResearchGate publication ID250925344

P2093author name stringHongtao Sun
John P Clancy
Deborah A Corey
Sharon M Rymut
Thomas J Kelley
James D Burgess
Alyssa Harker
P2860cites workHDAC6 is a microtubule-associated deacetylaseQ24298013
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stressQ24301895
Increased bioelectric potential difference across respiratory epithelia in cystic fibrosisQ70982010
Abnormal electrolyte composition of sweat in cystic fibrosis of the pancreasQ73318420
A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR functionQ74225407
Histone deacetylase 6 regulates human immunodeficiency virus type 1 infectionQ24535531
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosisQ24615395
HDAC6 regulates mitochondrial transport in hippocampal neuronsQ27326879
Microtubule acetylation promotes kinesin-1 binding and transport.Q27919704
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and preventionQ28240437
Aggresomes: a cellular response to misfolded proteinsQ28292275
Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosisQ28509055
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomesQ28572782
Microtubule-dependent movement of late endocytic vesicles in vitro: requirements for Dynein and KinesinQ28573171
Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neuronsQ28573203
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylationQ28585062
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubulesQ28590634
Activation of β-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant responseQ28729157
Acetylated microtubules are required for fusion of autophagosomes with lysosomesQ33751982
The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradationQ33799637
Cargo recognition failure is responsible for inefficient autophagy in Huntington's diseaseQ33814719
Identification of an acetylation site of Chlamydomonas alpha-tubulinQ34338575
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylationQ34956085
Regulatory role of β-arrestin-2 in cholesterol processing in cystic fibrosis epithelial cellsQ36020237
PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Q36113829
Cytoplasmic dynein-dependent vesicular transport from early to late endosomesQ36534832
Chronic inflammation in the cystic fibrosis lung: alterations in inter- and intracellular signalingQ36981240
Loss of CFTR results in reduction of histone deacetylase 2 in airway epithelial cellsQ37264720
In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.Q37374706
Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms.Q37802039
HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferaseQ39479197
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibitionQ39667316
Activation of the unfolded protein response by deltaF508 CFTR.Q39985153
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylationQ40152899
Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cellsQ40197237
Endoplasmic reticulum stress and the unfolded protein response regulate genomic cystic fibrosis transmembrane conductance regulator expressionQ40229391
Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATPQ40794305
Isolation and culture of airway epithelial cells from chronically infected human lungsQ43773707
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stressQ46059743
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteinsQ46621436
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth diseaseQ57244922
P433issue6
P921main subjectcystic fibrosisQ178194
P304page(s)L419-31
P577publication date2013-07-19
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titleReduced microtubule acetylation in cystic fibrosis epithelial cells
P478volume305

Reverse relations

cites work (P2860)
Q100415911Alleviation of depression-like behavior in a cystic fibrosis mouse model by Hdac6 depletion
Q36480411Cellular chloride and bicarbonate retention alters intracellular pH regulation in Cftr KO crypt epithelium
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Q89281684Coordination of microtubule acetylation and the actin cytoskeleton by formins
Q48137033Dynamic regulation of lysine acetylation: the balance between acetyltransferase and deacetylase activities
Q89238951Electrochemical measurement of membrane cholesterol correlates with CFTR function and is HDAC6-dependent
Q35059369Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes
Q36108378Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis
Q91937034HDAC6 depletion improves cystic fibrosis mouse airway responses to bacterial challenge
Q38763646Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells
Q33807836Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6.
Q38579962Inflammation and its genesis in cystic fibrosis
Q92189644PRC1 promotes GLI1-dependent osteopontin expression in association with the Wnt/β-catenin signaling pathway and aggravates liver fibrosis
Q36549113Role of Exchange Protein Activated by cAMP 1 in Regulating Rates of Microtubule Formation in Cystic Fibrosis Epithelial Cells
Q51742165The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux.