Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration

scientific article published on 28 February 2012

Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration is …
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scholarly articleQ13442814

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P356DOI10.1155/2012/258469
P932PMC publication ID3299296
P698PubMed publication ID22505896
P5875ResearchGate publication ID224050096

P50authorTatsuji NishiharaQ60316155
P2093author name stringChiaki Kitamura
Takahiko Morotomi
Tatsuji Nishihara
Ayako Washio
Masamichi Terashita
P2860cites workHistological evaluation of contaminated furcal perforation in dogs' teeth repaired by MTA with or without internal matrix.Q51088029
Laminin alpha2 is essential for odontoblast differentiation regulating dentin sialoprotein expression.Q52096064
Transforming growth factor-beta modulates proliferation and differentiation of mouse clonal osteoblastic MC3T3-E1 cells depending on their maturation stagesQ70265142
Influence of time of calcium hydroxide iodoform paste replacement in the treatment of root perforationsQ72447635
Cytotoxicity of root perforation repair materialsQ74847198
Dentin regeneration by dental pulp stem cell therapy with recombinant human bone morphogenetic protein 2Q80375463
Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralizationQ24309319
Dentin matrix proteinsQ28267456
Bone morphogenetic proteinsQ28300236
Dissection of the odontoblast differentiation process in vitro by a combination of FGF1, FGF2, and TGFbeta1Q28505177
Bone morphogenetic proteins: multifunctional regulators of vertebrate developmentQ29618986
Regulation of growth plate chondrogenesis by bone morphogenetic protein-2.Q33930375
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.Q33966602
The nature and functional significance of dentin extracellular matrix proteinsQ34301430
Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing miceQ35919695
A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft).Q36885933
Modulation of chondrocyte proliferation by ascorbic acid and BMP-2.Q36895283
Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signalingQ38291613
Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiationQ38355395
Bone morphogenetic protein 2 induces dental follicle cells to differentiate toward a cementoblast/osteoblast phenotypeQ38363817
Effects of lipopolysaccharide on newly established rat dental pulp-derived cell line with odontoblastic propertiesQ40077359
Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repairQ41759670
Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.Q43715840
Formation of dentinal bridge on surface of regenerated dental pulp in dentin defects by controlled release of fibroblast growth factor-2 from gelatin hydrogelsQ43870030
TGF-beta signaling from a three-dimensional perspective: insight into selection of partnersQ44107805
Formation of dentin-like particles in dentin defects above exposed pulp by controlled release of fibroblast growth factor 2 from gelatin hydrogelsQ46279187
Differential expression patterns of the dentin matrix proteins during mineralized tissue formation.Q46285333
Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III.Q46287190
Induction of dentin formation on canine amputated pulp by recombinant human bone morphogenetic proteins (BMP)-2 and -4.Q46295153
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectmorphogenesisQ815547
P304page(s)258469
P577publication date2012-02-28
P1433published inInternational Journal of DentistryQ26842127
P1476titlePossible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration
P478volume2012

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cites work (P2860)
Q92594202Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells
Q57493378Effects of human bone morphogenetic protein 2 () on tertiary dentin formation
Q38740868Functional Roles of NOD1 in Odontoblasts on Dental Pulp Innate Immunity
Q46273895Hey1 functions as a positive regulator of odontogenic differentiation in odontoblast‑lineage cells
Q42709014Stimulating effects of quercetin and phenamil on differentiation of human dental pulp cells
Q42286000The effect of erythropoietin on autologous stem cell-mediated bone regeneration

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