The YjbH adaptor protein enhances proteolysis of the transcriptional regulator Spx in Staphylococcus aureus

scientific article published on 22 December 2011

The YjbH adaptor protein enhances proteolysis of the transcriptional regulator Spx in Staphylococcus aureus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.06414-11
P932PMC publication ID3294810
P698PubMed publication ID22194450
P5875ResearchGate publication ID51920582

P50authorHanne IngmerQ48358502
Dorte FreesQ58859984
P2093author name stringJakob Engman
Claes von Wachenfeldt
Annika Rogstam
P2860cites workSpx-RNA polymerase interaction and global transcriptional control during oxidative stressQ24631020
A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulenceQ24650591
The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of SpxQ28488899
YjbH-enhanced proteolysis of Spx by ClpXP in Bacillus subtilis is inhibited by the small protein YirB (YuzO)Q28488959
Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesisQ29547610
Bridge over troubled waters: sensing stress by disulfide bond formationQ33548062
Genetic instability of the global regulator agr explains the phenotype of the xpr mutation in Staphylococcus aureus KSI9051.Q33730682
Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureusQ33983383
Sigma(B) activity depends on RsbU in Staphylococcus aureusQ33995741
Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase.Q34098302
A regulatory protein that interferes with activator-stimulated transcription in bacteriaQ34923289
Investigations into sigmaB-modulated regulatory pathways governing extracellular virulence determinant production in Staphylococcus aureusQ35075278
Staphylococcus aureus mutants with increased lysostaphin resistanceQ35075303
Proteolysis in Bacterial Regulatory CircuitsQ35564854
New role of the disulfide stress effector YjbH in β-lactam susceptibility of Staphylococcus aureusQ35598445
Improved single-copy integration vectors for Staphylococcus aureusQ36026375
ATP-dependent proteases of bacteria: recognition logic and operating principlesQ36639201
Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteriaQ36736444
Spx-dependent global transcriptional control is induced by thiol-specific oxidative stress in Bacillus subtilisQ37089682
Development of a mariner-based transposon and identification of Listeria monocytogenes determinants, including the peptidyl-prolyl isomerase PrsA2, that contribute to its hemolytic phenotypeQ37232523
Genetic analysis in Bacillus subtilisQ37479528
New vector for efficient allelic replacement in naturally nontransformable, low-GC-content, gram-positive bacteria.Q37597487
The clp proteases of Bacillus subtilis are directly involved in degradation of misfolded proteinsQ39499815
Cytochrome bd biosynthesis in Bacillus subtilis: characterization of the cydABCD operon.Q39569013
Two Spx proteins modulate stress tolerance, survival, and virulence in Streptococcus mutansQ40332860
Spx is a global effector impacting stress tolerance and biofilm formation in Staphylococcus aureusQ41668672
Mechanisms of adaptation to nitrosative stress in Bacillus subtilisQ41970230
Alternative roles of ClpX and ClpP in Staphylococcus aureus stress tolerance and virulenceQ43608975
Loss-of-function mutations in yjbD result in ClpX- and ClpP-independent competence development of Bacillus subtilisQ43796042
Proteomic discovery of cellular substrates of the ClpXP protease reveals five classes of ClpX-recognition signalsQ44384522
Redox-sensitive transcriptional control by a thiol/disulphide switch in the global regulator, Spx.Q45230251
An improved tetracycline-inducible expression vector for Staphylococcus aureus.Q46256811
Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress toleranceQ47919213
Plasmids for ectopic integration in Bacillus subtilis.Q48057756
Staphylococcal coagulase; mode of action and antigenicity.Q51043511
Plasmids designed to alter the antibiotic resistance expressed by insertion mutations in Bacillus subtilis, through in vivo recombination.Q54205674
SpxB RegulatesO-Acetylation-dependent Resistance ofLactococcus lactisPeptidoglycan to HydrolysisQ60181267
Construction of single-copy integration vectors for Staphylococcus aureusQ68250938
Properties of a cryptic high-frequency transducing phage in Staphylococcus aureusQ68398098
Overexpression of sigma factor, sigma(B), urges Staphylococcus aureus to thicken the cell wall and to resist beta-lactamsQ74630591
YjbH is a novel negative effector of the disulphide stress regulator, Spx, in Bacillus subtilisQ81379796
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
Staphylococcus aureusQ188121
P304page(s)1186-1194
P577publication date2011-12-22
P1433published inJournal of BacteriologyQ478419
P1476titleThe YjbH adaptor protein enhances proteolysis of the transcriptional regulator Spx in Staphylococcus aureus
P478volume194

Reverse relations

cites work (P2860)
Q34024940Adaptor bypass mutations of Bacillus subtilis spx suggest a mechanism for YjbH-enhanced proteolysis of the regulator Spx by ClpXP
Q36077058An In Vivo Selection Identifies Listeria monocytogenes Genes Required to Sense the Intracellular Environment and Activate Virulence Factor Expression.
Q90383078Complete Genome Sequence of Carotenoid-Producing Enterococcus gilvus CR1, Isolated from Raw Cow's Milk
Q92458663Contribution of YjbIH to Virulence Factor Expression and Host Colonization in Staphylococcus aureus
Q37321981Evidence that Oxidative Stress Induces spxA2 Transcription in Bacillus anthracis Sterne through a Mechanism Requiring SpxA1 and Positive Autoregulation
Q39757341Exploring structure and interactions of the bacterial adaptor protein YjbH by crosslinking mass spectrometry
Q36525721Geobacillus thermodenitrificans YjbH recognizes the C-terminal end of Bacillus subtilis Spx to accelerate Spx proteolysis by ClpXP.
Q100512225Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy
Q38847411Neutrophil-generated oxidative stress and protein damage in Staphylococcus aureus
Q90441935Regulatory circuits controlling Spx levels in Streptococcus mutans
Q37124962Residue substitutions near the redox center of Bacillus subtilis Spx affect RNA polymerase interaction, redox control, and Spx-DNA contact at a conserved cis-acting element
Q36081351Rifampin Resistance rpoB Alleles or Multicopy Thioredoxin/Thioredoxin Reductase Suppresses the Lethality of Disruption of the Global Stress Regulator spx in Staphylococcus aureus
Q41962594Role of adaptor TrfA and ClpPC in controlling levels of SsrA-tagged proteins and antitoxins in Staphylococcus aureus
Q36823924Roles of adaptor proteins in regulation of bacterial proteolysis
Q36158472Stepwise decrease in daptomycin susceptibility in clinical Staphylococcus aureus isolates associated with an initial mutation in rpoB and a compensatory inactivation of the clpX gene
Q41717997The ClpXP protease is dispensable for degradation of unfolded proteins in Staphylococcus aureus
Q41840280The Copper Efflux Regulator CueR Is Subject to ATP-Dependent Proteolysis in Escherichia coli.
Q36969735The Staphylococcus aureus thiol/oxidative stress global regulator Spx controls trfA, a gene implicated in cell wall antibiotic resistance
Q46355450The role of thiol oxidative stress response in heat-induced protein aggregate formation during thermotolerance in Bacillus subtilis
Q38365541Thiol-based redox switches in prokaryotes
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Q89965318YjbH Solubility Controls Spx in Staphylococcus aureus: Implication for MazEF Toxin-Antitoxin System Regulation

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