Serotonin 1A auto-receptors are not sufficient to modulate anxiety in mice

scientific article published on 22 May 2013

Serotonin 1A auto-receptors are not sufficient to modulate anxiety in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/EJN.12260
P698PubMed publication ID23701504

P50authorLukasz PiszczekQ91018330
P2093author name stringAnna Wyrzykowska
Agnieszka Piszczek
Cornelius Thilo Gross
Enrica Audero
Kevin Schlax
P2860cites workSignal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonistQ24644854
Increased anxiety of mice lacking the serotonin1A receptorQ24655613
Transcriptional regulation of the 5-HT1A receptor: implications for mental illnessQ26999691
Synthesis of serotonin by a second tryptophan hydroxylase isoformQ28513857
Serotonin receptor 1A knockout: an animal model of anxiety-related disorderQ28592514
Differential occupancy of somatodendritic and postsynaptic 5HT(1A) receptors by pindolol: a dose-occupancy study with [11C]WAY 100635 and positron emission tomography in humansQ31884011
Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: convergent data from Tph2 knockout miceQ33404248
Median and Dorsal Raphe Neurons Are Not Electrophysiologically IdenticalQ33696834
Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrusQ33720433
Serotonin 1A receptors in human and monkey prefrontal cortex are mainly expressed in pyramidal neurons and in a GABAergic interneuron subpopulation: implications for schizophrenia and its treatmentQ34818583
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxietyQ35008700
The developmental origins of anxietyQ35811903
Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in miceQ36108365
Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant miceQ36759748
Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out miceQ37361257
Distinguishing characteristics of serotonin and non-serotonin-containing cells in the dorsal raphe nucleus: electrophysiological and immunohistochemical studiesQ39424055
Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences.Q40485805
Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors.Q41967962
Role of the medial prefrontal cortex in 5-HT1A receptor-induced inhibition of 5-HT neuronal activity in the rat.Q42102174
5-HT1A receptor expression in pyramidal neurons of cortical and limbic brain regionsQ42479630
Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressantsQ42717226
Serotonin receptor 1A modulates actin dynamics and restricts dendritic growth in hippocampal neuronsQ43012955
5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmissionQ43572910
Electrophysiological evidence for postsynaptic 5-HT(1A) receptor control of dorsal raphe 5-HT neuronesQ43668135
Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adultQ43937540
Autonomic changes associated with enhanced anxiety in 5-HT(1A) receptor knockout miceQ44133478
The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brainQ44247651
In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptorsQ44482985
Expression of serotonin1A and serotonin2A receptors in pyramidal and GABAergic neurons of the rat prefrontal cortex.Q44872295
Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?Q44883665
Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine (5-HT)1A, 5-HT2A, and 5-HT7 receptors.Q44902336
Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.Q44978629
Identifying molecular substrates in a mouse model of the serotonin transporter x environment risk factor for anxiety and depression.Q46940797
Suppression of serotonin neuron firing increases aggression in miceQ47888141
The inhibitory effect of 8-OH-DPAT on the firing activity of dorsal raphe serotoninergic neurons in rats is attenuated by lesion of the frontal cortexQ48134507
Postsynaptic 5-HT1A receptors control 5-HT release in the rat medial prefrontal cortexQ48178911
Role of somatodendritic 5-HT autoreceptors in modulating 5-HT neurotransmission.Q48294709
Acute 5-HT₁A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions.Q48432408
Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtypeQ48468938
Production of specific anti-rat 5-HT1A receptor antibodies in rabbits injected with a synthetic peptideQ48878476
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)2621-2627
P577publication date2013-05-22
P1433published inEuropean Journal of NeuroscienceQ5412733
P1476titleSerotonin 1A auto-receptors are not sufficient to modulate anxiety in mice
P478volume38

Reverse relations

cites work (P2860)
Q26744108Concordance and incongruence in preclinical anxiety models: Systematic review and meta-analyses
Q36915393Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment.
Q35115387Modulation of anxiety by cortical serotonin 1A receptors
Q33719414Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression