Uroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene sequence and evidence for two conserved glycines essential for enzymatic activity

scientific article published on May 1992

Uroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene sequence and evidence for two conserved glycines essential for enzymatic activity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1432-1033.1992.TB16868.X
P698PubMed publication ID1576986
P5875ResearchGate publication ID21578716

P50authorAnna ChełstowskaQ65963256
P2093author name stringJ Rytka
R Labbe-Bois
L Harrison
J Kushner
P Labbe
J R Garey
P2860cites workA technique for radiolabeling DNA restriction endonuclease fragments to high specific activityQ26778490
Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis.Q27931941
A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coliQ28131613
The structure, function and evolution of cytochromesQ28611215
Purification of uroporphyrinogen decarboxylase from human erythrocytes. Immunochemical evidence for a single protein with decarboxylase activity in human erythrocytes and liverQ41963947
The effects in vivo of mutationally modified uroporphyrinogen decarboxylase in different hem12 mutants of baker's yeast (Saccharomyces cerevisiae).Q41985126
Biosynthesis of porphyrins in Rhodopseudomonas palustris--VI. The effect of metals, thiols and other reagents on the activity of uroporphyrinogen decarboxylaseQ42218576
Nucleotide sequence of the Synechococcus sp. PCC7942 branching enzyme gene (glgB): expression in Bacillus subtilisQ42630975
Modified uroporphyrinogen decarboxylase activity in a yeast mutant which mimics porphyria cutanea tardaQ42867964
Investigations of rat liver uroporphyrinogen decarboxylase. Comparisons of porphyrinogens I and III as substrates and the inhibition by porphyrinsQ42931876
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
P304page(s)1011-1016
P577publication date1992-05-01
P1433published inFEBS JournalQ1388041
P1476titleUroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene sequence and evidence for two conserved glycines essential for enzymatic activity
P478volume205

Reverse relations

cites work (P2860)
Q73715194A conserved cysteine residue in yeast uroporphyrinogen decarboxylase is not essential for enzymatic activity
Q28507743A mouse model of familial porphyria cutanea tarda
Q28288050A zebrafish model for hepatoerythropoietic porphyria
Q39940231Cloning and characterization of the Bacillus subtilis hemEHY gene cluster, which encodes protoheme IX biosynthetic enzymes
Q27634421Crystal structure and substrate binding modeling of the uroporphyrinogen-III decarboxylase from Nicotiana tabacum. Implications for the catalytic mechanism
Q35759759Crystal structure of uroporphyrinogen decarboxylase from Bacillus subtilis
Q44981564Functional characterisation and transcriptional regulation of the KlHEM12 gene from Kluyveromyces lactis.
Q27931002Identification of amino acid changes affecting yeast uroporphyrinogen decarboxylase activity by sequence analysis of hem12 mutant alleles
Q27931650Identification of rate-limiting steps in yeast heme biosynthesis
Q72285937Isolation and characterization of extragenic mutations affecting the expression of the uroporphyrinogen decarboxylase gene (HEM12) in Sacharomyces cerevisiae
Q36686039Isolation, sequencing and expression of cDNA sequences encoding uroporphyrinogen decarboxylase from tobacco and barley.
Q71938749Mutational analysis of human uroporphyrinogen decarboxylase
Q48073846Nucleotide sequence of the Rhodobacter capsulatus hemE gene
Q42152506Purification and properties of the uroporphyrinogen decarboxylase from Rhodobacter sphaeroides
Q34408334Sequence and transcript analysis of a novel Methanosarcina barkeri methyltransferase II homolog and its associated corrinoid protein homologous to methionine synthase
Q40433950Uroporphyrinogen decarboxylase
Q24676183Uroporphyrinogen decarboxylase: complete human gene sequence and molecular study of three families with hepatoerythropoietic porphyria

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