| scholarly article | Q13442814 |
| P50 | author | Paul Dent | Q73523499 |
| P2093 | author name string | Paul B Fisher | |
| Steven Grant | |||
| Margaret A Park | |||
| James Norris | |||
| Guo Zhang | |||
| Philip B Hylemon | |||
| P2860 | cites work | Global cancer statistics, 2002 | Q27860562 |
| Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death | Q28240733 | ||
| The dsRNA protein kinase PKR: virus and cell control | Q28298945 | ||
| Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling | Q28568378 | ||
| Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis. | Q33946679 | ||
| Histone acetylation and chromatin remodeling | Q34219273 | ||
| The CD95(APO-1/Fas) DISC and beyond | Q35091401 | ||
| Histone deacetylases | Q35193642 | ||
| MAPK pathways in radiation responses | Q35208830 | ||
| Death receptor-induced cell killing | Q35592675 | ||
| Management of cutaneous melanoma | Q35877006 | ||
| The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress | Q35950143 | ||
| Sorafenib: scientific rationales for single-agent and combination therapy in clear-cell renal cell carcinoma | Q36373477 | ||
| Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment | Q36395200 | ||
| Sorafenib | Q36407379 | ||
| Assessment of developmental toxicity of vorinostat, a histone deacetylase inhibitor, in Sprague-Dawley rats and Dutch Belted rabbits | Q36733777 | ||
| Radiation-induced cell signaling: inside-out and outside-in | Q36760964 | ||
| Sorafenib: delivering a targeted drug to the right targets | Q36817095 | ||
| B-Raf kinase inhibitors for cancer treatment | Q36875829 | ||
| Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation | Q36922674 | ||
| From molecular biology to targeted therapies for hepatocellular carcinoma: the future is now. | Q37034876 | ||
| OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells | Q37172898 | ||
| Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation | Q37172903 | ||
| Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells | Q38870039 | ||
| AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in precl | Q40093939 | ||
| Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1. | Q40102679 | ||
| Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation | Q40106651 | ||
| Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma. | Q40149920 | ||
| Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation | Q40383692 | ||
| Activation of extracellular signal-regulated kinases ERK1 and ERK2 induces Bcl-xL up-regulation via inhibition of caspase activities in erythropoietin signaling | Q40661974 | ||
| Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. | Q40662652 | ||
| Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53. | Q42522917 | ||
| Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. | Q42800979 | ||
| Apicidin, a Histone Deacetylase Inhibitor, Induces Apoptosis and Fas/Fas Ligand Expression in Human Acute Promyelocytic Leukemia Cells | Q43792226 | ||
| Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation | Q44683463 | ||
| The multikinase inhibitor sorafenib induces apoptosis in highly imatinib mesylate-resistant bcr/abl+ human leukemia cells in association with signal transducer and activator of transcription 5 inhibition and myeloid cell leukemia-1 down-regulation | Q44930505 | ||
| Activity of suberoylanilide hydroxamic Acid against human breast cancer cells with amplification of her-2. | Q46689478 | ||
| Kinase inhibitors and cytotoxic drug resistance | Q53898623 | ||
| P433 | issue | 7 | |
| P921 | main subject | autophagy | Q288322 |
| ceramides | Q424213 | ||
| P304 | page(s) | 929-931 | |
| P577 | publication date | 2008-10-05 | |
| P1433 | published in | Autophagy | Q1255295 |
| P1476 | title | Regulation of autophagy by ceramide-CD95-PERK signaling | |
| P478 | volume | 4 |
| Q41768831 | C6-Ceramide Enhances Phagocytic Activity of Kupffer Cells through the Production of Endogenous Ceramides |
| Q38067062 | Ceramide-orchestrated signalling in cancer cells. |
| Q35057070 | Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. |
| Q30829403 | Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation. |
| Q90356918 | GD2 ganglioside-binding antibody 14G2a and specific aurora A kinase inhibitor MK-5108 induce autophagy in IMR-32 neuroblastoma cells |
| Q33633401 | Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy. |
| Q33926871 | MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism |
| Q36248193 | MDA-7/IL-24: multifunctional cancer killing cytokine |
| Q39490156 | Modulation of pediatric brain tumor autophagy and chemosensitivity |
| Q40442443 | Murine model of long-term obstructive jaundice |
| Q34373087 | New role for EMD (emerin), a key inner nuclear membrane protein, as an enhancer of autophagosome formation in the C16-ceramide autophagy pathway |
| Q35192134 | PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment |
| Q33931451 | PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells |
| Q39903161 | Regulation of HMGB1 release by autophagy |
| Q37930541 | Sphingolipid Metabolism and Analysis in Metabolic Disease |
| Q37808219 | Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance |
| Q37858077 | Targeting autophagy during cancer therapy to improve clinical outcomes |
| Q37707832 | Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer |
| Q33720239 | The pleiotropic roles of sphingolipid signaling in autophagy |
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