| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S11357-012-9476-9 |
| P8608 | Fatcat ID | release_vfedfpeounhw3ibztwt54mkhyq |
| P932 | PMC publication ID | 3776094 |
| P698 | PubMed publication ID | 23001818 |
| P5875 | ResearchGate publication ID | 232657734 |
| P2093 | author name string | David Kipling | |
| Julia W Grimstead | |||
| Terence Davis | |||
| Amy J C Brook | |||
| Michal J Rokicki | |||
| Hannah S E Tivey | |||
| P2860 | cites work | Rothmund-Thomson syndrome | Q21202881 |
| Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes | Q22008619 | ||
| Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation | Q24302534 | ||
| Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4 | Q24323062 | ||
| RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway | Q28277686 | ||
| Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome | Q28505974 | ||
| RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance | Q28771762 | ||
| Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
| The serial cultivation of human diploid cell strains | Q29547356 | ||
| A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen | Q29615061 | ||
| Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome | Q33217275 | ||
| Instability of lymphocyte chromosomes in a girl with Rothmund-Thomson syndrome | Q33674584 | ||
| Rothmund-Thomson syndrome: two case reports show heterogeneous cutaneous abnormalities, an association with genetically programmed ageing changes, and increased chromosomal radiosensitivity | Q33677997 | ||
| What geriatricians should know about the Werner syndrome | Q33731898 | ||
| Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts | Q33965486 | ||
| Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes | Q34106524 | ||
| Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. | Q34195221 | ||
| A model for the phenotypic presentation of Werner's syndrome. | Q34482220 | ||
| Werner Syndrome as an example of inflamm-aging: possible therapeutic opportunities for a progeroid syndrome? | Q34549949 | ||
| What can progeroid syndromes tell us about human aging? | Q34550676 | ||
| Molecular bases of progeroid syndromes. | Q34567458 | ||
| Growth retardation and skin abnormalities of the Recql4-deficient mouse. | Q52551576 | ||
| Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of ataxia telangiectasia and Werner syndrome fibroblasts. | Q53527908 | ||
| RECQL4-deficient cells are hypersensitive to oxidative stress/damage: Insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome. | Q53624157 | ||
| Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor. | Q53644823 | ||
| Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence | Q58613376 | ||
| Osteogenic sarcoma and Rothmund Thomson syndrome | Q68121314 | ||
| A case of Rothmund-Thomson syndrome with reduced DNA repair capacity | Q70596020 | ||
| Rothmund-Thomson syndrome in siblings: evidence for acquired in vivo mosaicism | Q71340549 | ||
| Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells | Q73106953 | ||
| Excision repair defect in Rothmund Thomson syndrome | Q77401209 | ||
| [Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases] | Q78017183 | ||
| Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia | Q78850608 | ||
| Homologous recombination and maintenance of genome integrity: cancer and aging through the prism of human RecQ helicases | Q34772977 | ||
| MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication | Q34998668 | ||
| p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype | Q35007977 | ||
| RecQ helicases: suppressors of tumorigenesis and premature aging. | Q35152970 | ||
| Shared phenotypes among segmental progeroid syndromes suggest underlying pathways of aging | Q36059159 | ||
| The gene responsible for Werner syndrome may be a cell division "counting" gene | Q36740224 | ||
| The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging | Q36802178 | ||
| Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents | Q36978188 | ||
| Can we intervene in human ageing? | Q37592333 | ||
| Rothmund-Thomson syndrome helicase, RECQ4: on the crossroad between DNA replication and repair | Q37680196 | ||
| Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome | Q38974348 | ||
| Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells | Q39392000 | ||
| Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis | Q39445352 | ||
| Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage | Q39452086 | ||
| The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells. Role of the N-terminal region of RECQL4 in cells | Q39604432 | ||
| Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence | Q39674577 | ||
| Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence | Q40140877 | ||
| Nuclear import and retention domains in the amino terminus of RECQL4. | Q40179530 | ||
| Replicative senescence in sheep fibroblasts is a p53 dependent process. | Q40467627 | ||
| Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts | Q40514053 | ||
| High Intensity ras Signaling Induces Premature Senescence by Activating p38 Pathway in Primary Human Fibroblasts | Q40620874 | ||
| Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms | Q40666765 | ||
| Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway | Q40671353 | ||
| Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. | Q41130163 | ||
| The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication | Q41491045 | ||
| Enhanced radiosensitivity and defective DNA repair in cultured fibroblasts derived from Rothmund Thomson syndrome patients | Q41623174 | ||
| Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability | Q43579908 | ||
| Clonal lines of aneuploid cells in Rothmund-Thomson syndrome | Q44528713 | ||
| Dysadipocytokinemia in werner syndrome and its recovery by treatment with pioglitazone | Q45081303 | ||
| Identification of new RECQL4 mutations in Caucasian Rothmund-Thomson patients and analysis of sensitivity to a wide range of genotoxic agents | Q46490907 | ||
| Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis | Q47639432 | ||
| P275 | copyright license | Creative Commons Attribution 2.0 Generic | Q19125117 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P304 | page(s) | 1767-1783 | |
| P577 | publication date | 2012-09-22 | |
| P1433 | published in | Age | Q4691832 |
| P1476 | title | Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome | |
| P478 | volume | 35 |
| Q35008261 | Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence |
| Q34278129 | Opposite roles for p38MAPK-driven responses and reactive oxygen species in the persistence and resolution of radiation-induced genomic instability |
| Q33625254 | Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies |
| Q33720176 | Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice |
| Q41932634 | Small molecule inhibition of p38 MAP kinase extends the replicative life span of human ATR-Seckel syndrome fibroblasts |
| Q39861660 | p38 (MAPK) stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes |
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