Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family

scientific article published on July 1989

Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.3.7.1086
P698PubMed publication ID2550322
P5875ResearchGate publication ID20606475

P2093author name stringRevazova E
Grigorian M
Ebralidze A
Tulchinsky E
Lukanidin E
Afanasyeva A
Senin V
P4510describes a project that usesCSML-0Q54814668
CSML-100Q54814669
P433issue7
P921main subjectcell lineQ21014462
protein familyQ417841
P304page(s)1086-1093
P577publication date1989-07-01
P1433published inGenes & DevelopmentQ1524533
P1476titleIsolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family
P478volume3

Reverse relations

described by source (P1343)
Q54814668CSML-0
Q54814669CSML-100

cites work (P2860)
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Q383316123'-99mTc-labeling and biodistribution of a CAPL antisense oligodeoxynucleotide
Q73067566A kappaB-related binding site is an integral part of the mts1 gene composite enhancer element located in the first intron of the gene
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Q39212411Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion.
Q37209254Biomarkers for epithelial-mesenchymal transitions
Q50941390Boundary cap neural crest stem cell transplants contribute Mts1/S100A4-expressing cells in the glial scar.
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Q63966034Expression of S100A4 protein is associated with metastasis and reduced survival in human bladder cancer
Q36692461Expression of S100A4, E-cadherin, alpha- and beta-catenin in breast cancer biopsies
Q40824790Expression of metastasis-associated mts1 gene is co-induced with membrane type-1 matrix metalloproteinase (MT1-MMP) during oncogenic transformation and tubular formation of Madin Darby canine kidney (MDCK) epithelial cells
Q47142687Expression of miR-149-3p inhibits proliferation, migration, and invasion of bladder cancer by targeting S100A4.
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Q47662103Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity
Q33781682Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells
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Q42279613Increased expression of S100A6 at the invading fronts of the primary lesion and liver metastasis in patients with colorectal adenocarcinoma
Q73594094Induction of S100A4 gene expression inhibits in vitro invasiveness of human squamous cell carcinoma, KOSC-3 cells
Q73393706Induction of c-met proto-oncogene expression at the metastatic site
Q28141200Interaction in vivo and in vitro of the metastasis-inducing S100 protein, S100A4 (p9Ka) with S100A1
Q37176639Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes
Q41452155Involvement of S100-related calcium-binding protein pEL98 (or mts1) in cell motility and tumor cell invasion
Q43504846Isoproterenol-induced myocardial injury resulting in altered S100A4 and S100A11 protein expression in the rat.
Q77598559KAI1, a new metastasis suppressor gene, is reduced in metastatic hepatocellular carcinoma
Q34113420Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1).
Q58001353Metastasis-associated Mts1 (S100A4) Protein Modulates Protein Kinase C Phosphorylation of the Heavy Chain of Nonmuscle Myosin
Q63362549Metastasis-associated protein Mts1 (S100A4) inhibits CK2-mediated phosphorylation and self-assembly of the heavy chain of nonmuscle myosin
Q39707595Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice
Q44918219Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.
Q34127108Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4.
Q41107306Modulation of S‐100 genes response to growth conditions in human epithelial tumor cells
Q41484329Modulation of mts1 expression in mouse and human normal and tumor cells
Q90179421Molecular Mechanisms by Which S100A4 Regulates the Migration and Invasion of PGCCs With Their Daughter Cells in Human Colorectal Cancer
Q33481737Molecular dynamics simulation of S100B protein to explore ligand blockage of the interaction with p53 protein
Q42151468Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein
Q33536501Molecular mechanisms of nonmuscle myosin-II regulation
Q93532181New nucleotide sequence data on the EMBL File Server
Q26852520Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis
Q73038419Oligomeric forms of the metastasis-related Mts1 (S100A4) protein stimulate neuronal differentiation in cultures of rat hippocampal neurons
Q37310690Opposite roles of metastasin (S100A4) in two potentially tumoricidal mechanisms involving human lymphocyte protein Tag7 and Hsp70.
Q30795307Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.
Q36619311Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas
Q41418678Overexpression of the 18A2/mts1 gene and down-regulation of the TIMP-2 gene in invasive human glioma cell lines in vitro
Q71797516Papillary and mucoepidermoid carcinoma of the thyroid with anaplastic transformation: a case report with histologic and immunohistochemical findings that support a provocative histogenetic hypothesis
Q35919333Prognostic correlation between MTA2 expression level and colorectal cancer.
Q41867135Protein S100A4: too long overlooked by pathologists?
Q33935212Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor
Q22010926Psoriasin (S100A7) expression and invasive breast cancer
Q70807777Refined mapping of the psoriasin gene S100A7 to chromosome 1cen-q21
Q90128825Relationship between S100A4 protein expression and pre-operative serum CA19.9 levels in pancreatic carcinoma and its prognostic significance
Q26765942Role of S100 Proteins in Colorectal Carcinogenesis
Q47153204Role of metastasis-induced protein S100A4 in human non-tumor pathophysiologies.
Q64996301S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer.
Q33597019S100A4 and metastasis: a small actor playing many roles
Q37959812S100A4 calcium-binding protein is key player in tumor progression and metastasis: preclinical and clinical evidence
Q34839397S100A4 expression in xenograft tumors of human carcinoma cell lines is induced by the tumor microenvironment
Q26743403S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction
Q42700673S100A4 in cancer progression and metastasis: A systematic review
Q36166931S100A4 in esophageal cancer: is this the one to blame?
Q42955189S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.
Q38334964S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity
Q35079996S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.
Q28278577S100A4, a mediator of metastasis
Q58582218S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition
Q35104378S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance
Q35083293S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy
Q92283914S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis
Q77742081Sequence-specific chemical shift assignment and chemical shift indexing of murine apo-Mts1
Q74555402Sequence-specific chemical shift assignment of calcium-loaded murine S100A4
Q37502777Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth
Q24562136Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E
Q41103578Spectral studies on the calcium-binding properties of Mts1 protein and its interaction with target protein
Q34181448Sumoylation and Nuclear Translocation of S100A4 Regulate IL-1β-mediated Production of Matrix Metalloproteinase-13
Q42115625Suppression of metastasis-associated S100A4 gene expression by gamma-interferon in human colon adenocarcinoma cells
Q31152739The CO-Regulation Database (CORD): a tool to identify coordinately expressed genes
Q34556703The S100A4 D10V polymorphism is related to cell migration ability but not drug resistance in gastric cancer cells
Q42969892The S100A4 Oncoprotein Promotes Prostate Tumorigenesis in a Transgenic Mouse Model: Regulating NFκB through the RAGE Receptor.
Q41547351The biochemistry of cancer dissemination
Q28207905The dimerization interface of the metastasis-associated protein S100A4 (Mts1): in vivo and in vitro studies
Q36131038The metastasis associated protein S100A4: role in tumour progression and metastasis
Q34560305The metastasis promoting protein S100A4 levels associate with disease activity rather than cancer development in patients with idiopathic inflammatory myopathies
Q40787009The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor
Q33343721The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
Q33943227The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers
Q47282405The role of S100A4 protein in anticancer cytotoxicity: its presence is required on the surface of CD4+CD25+PGRPs+S100A4+ lymphocyte and undesirable on the surface of target cells.
Q35788792Thymosin-beta4 regulates motility and metastasis of malignant mouse fibrosarcoma cells
Q36519045Transcription factors control invasion: AP-1 the first among equals
Q24563784Transcriptional analysis of the mts1 gene with specific reference to 5' flanking sequences
Q41094547Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor.
Q30164820Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation
Q28208109Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction
Q40391669Tumour cell migration in the central nervous system
Q41265445Turned on by Ca2+! The physiology and pathology of Ca(2+)-binding proteins in the retina
Q35229115VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

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