Autoantibodies targeting AT1 receptor from patients with acute coronary syndrome upregulate proinflammatory cytokines expression in endothelial cells involving NF-κB pathway

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Autoantibodies targeting AT1 receptor from patients with acute coronary syndrome upregulate proinflammatory cytokines expression in endothelial cells involving NF-κB pathway is …
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scholarly articleQ13442814

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P356DOI10.1155/2014/342693
P8608Fatcat IDrelease_ndbhawx3tbc5hai2tq55hfp2n4
P932PMC publication ID4266766
P698PubMed publication ID25762441
P5875ResearchGate publication ID273467251

P2093author name stringXiang Cheng
Feng Zhu
Zhi Li
Yuanyuan Lv
Songhai Li
Qiutang Zeng
Yuhua Liao
Wenping Zhou
Yumiao Wei
Weijuan Li
Zihua Zhou
Yaoqi Chen
Mengyang Liao
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Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiologyQ28292037
The angiotensin II AT1 receptor structure-activity correlations in the light of rhodopsin structureQ28297667
Antibodies against AT1 receptors are associated with vascular endothelial and smooth muscle function impairment: protective effects of hydroxysafflor yellow AQ28534198
Advanced glycation end-products enhance calcification in vascular smooth muscle cellsQ28575353
Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertensionQ28575913
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
Signaling to NF-kappaBQ29547844
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Progress and challenges in translating the biology of atherosclerosisQ29619982
Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorptionQ30814535
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Exposure to AT1 receptor autoantibodies during pregnancy increases susceptibility of the maternal heart to postpartum ischemia-reperfusion injury in ratsQ34072217
Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathyQ34646571
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Renin-angiotensin system and atherothrombotic disease: from genes to treatmentQ35136362
Activating auto-antibodies against the AT1 receptor in preeclampsiaQ36010629
Agonistic AT(1) receptor autoantibody increases in serum of patients with refractory hypertension and improves Ca(2+) mobilization in cultured rat vascular smooth muscle cellsQ36295460
Inflammation and cardiovascular disease mechanismsQ36392615
Inflammation and atherosclerosis: novel insights into plaque formation and destabilizationQ36495025
Nuclear factor-kappaB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injuryQ36516285
Atherosclerotic plaque stability--what determines the fate of a plaque?Q37332292
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NF-κB, inflammation, and metabolic disease.Q37825008
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Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.Q42937193
Autoantibodies against AT1-receptor and alpha1-adrenergic receptor in patients with hypertensionQ44162378
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidaseQ44385661
Agonistic autoantibodies directed against the angiotensin II AT1 receptor in patients with preeclampsiaQ44413491
Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trialQ44783935
Randomized trial of atorvastatin for reduction of myocardial damage during coronary intervention: results from the ARMYDA (Atorvastatin for Reduction of MYocardial Damage during Angioplasty) study.Q44995469
Cardiac remodeling after long-term stimulation by antibodies against the alpha1-adrenergic receptor in ratsQ45216646
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Oxidized low-density lipoprotein-induced proinflammatory cytokine response in macrophages are suppressed by CD4CD25(+)Foxp3(+) regulatory T cells through downregulating toll like receptor 2-mediated activation of NF-kappaB.Q45303264
Arterial structural changes in rats immunized by AT1-receptor peptideQ46605218
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients.Q52905846
Is parvovirus B19 the cause for autoimmunity against the angiotensin II type receptor?Q52928690
Th1/Th2 Functional Imbalance After Acute Myocardial Infarction: Coronary Arterial Inflammation or Myocardial InflammationQ57524912
Functional autoimmune epitope on alpha 1-adrenergic receptors in patients with malignant hypertensionQ71662795
Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instabilityQ73590707
AT(1) receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factorQ73815485
Angiotensin II activates nuclear transcription factor kappaB through AT(1) and AT(2) in vascular smooth muscle cells: molecular mechanismsQ73919597
Autoantibodies against the angiotensin receptor (AT1) in patients with hypertensionQ74126541
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Functional and structural characterization of anti-beta1-adrenoceptor autoantibodies of spontaneously hypertensive ratsQ79201165
Inhibition of IFN regulatory factor-1 down-regulate Th1 cell function in patients with acute coronary syndromeQ83005979
Increased Levels of Soluble Vascular Endothelial Cadherin are Associated with Poor Outcome in Severe SepsisQ85166357
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectendotheliumQ111140
acute coronary syndromeQ266018
NF-κBQ411114
autoantibodyQ785022
P304page(s)342693
P577publication date2014-11-30
P1433published inJournal of Immunology ResearchQ26841936
P1476titleAutoantibodies targeting AT1 receptor from patients with acute coronary syndrome upregulate proinflammatory cytokines expression in endothelial cells involving NF-κB pathway
P478volume2014

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cites work (P2860)
Q39334546Anti-calreticulin antibodies and calreticulin in sera of patients diagnosed with dilated or hypertrophic cardiomyopathy.
Q90599535Autoantibodies against AT1 Receptor Contribute to Vascular Aging and Endothelial Cell Senescence
Q55043767Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro.
Q91432481Dynamic changes in chemosensitivity immune predictors in patients with hypopharyngeal cancer treated with induction chemotherapy
Q90365019MicroRNA-145 is involved in endothelial cell dysfunction and acts as a promising biomarker of acute coronary syndrome
Q37713975Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
Q38723456Role of Inflammation and Immunity in Hypertension: Recent Epidemiological, Laboratory, and Clinical Evidence

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