The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour

scientific article published on 17 October 2017

The developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0186333
P932PMC publication ID5645110
P698PubMed publication ID29040332

P50authorRyuji FukuzawaQ89137243
Tony ReeveQ105243714
Ian MorisonQ40135423
P2093author name stringMatthew R Anaka
P2860cites workDevelopment of glomerular endothelial cells, podocytes and mesangial cells in the human fetus and infantQ24304110
Polyductin, the PKHD1 gene product, comprises isoforms expressed in plasma membrane, primary cilium, and cytoplasmQ24305942
Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changesQ24313230
Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumorsQ24313408
CITED1 expression in Wilms' tumor and embryonic kidneyQ24337902
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transitionQ24685187
Aquaporin Expression in Normal Human Kidney and in Renal DiseaseQ27919644
The metanephric blastema differentiates into collecting system and nephron epithelia in vitroQ28291337
Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2Q28504535
Wnt/beta-catenin signaling regulates nephron induction during mouse kidney developmentQ28506499
Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo.Q40229890
Expression of glial cell line-derived neurotrophic factor and neurturin in mature kidney, nephrogenic rests, and nephroblastoma: possible role as differentiating factorsQ40579031
GDNF expression in Wilms tumorQ40803571
Precursor lesions of Wilms tumor: clinical and biological implicationsQ40851883
Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epitheliumQ41078366
Evidence for Clonal Development of Wilmsʼ TumorQ41155572
Sequential WT1 and CTNNB1 mutations and alterations of beta-catenin localisation in intralobar nephrogenic rests and associated Wilms tumours: two case studiesQ41809711
Mesenchymal to epithelial conversion in rat metanephros is induced by LIF.Q42614278
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.Q43213014
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidneyQ45178758
Transient neonatal cystinuriaQ45239975
WTX mutations can occur both early and late in the pathogenesis of Wilms tumourQ45801538
Immuno-localization of CD44 and osteopontin in developing human kidneyQ46372373
Atlas of Hox gene expression in the developing kidneyQ47887133
Myogenesis in Wilms' tumors is associated with mutations of the WT1 gene and activation of Bcl-2 and the Wnt signaling pathwayQ48013596
Expression of Human Mucin Genes During Normal and Abnormal Renal DevelopmentQ53374882
Lectin histochemistry of Wilms' tumor. Comparison with normal adult and fetal kidney.Q53678540
Genetic clonality is a feature unifying nephroblastomas regardless of the variety of morphological subtypesQ57636682
Clonality and loss of heterozygosity of WT genes are early events in the pathogenesis of nephroblastomasQ57636692
Expression of intermediate filament proteins in fetal and adult human kidney: modulations of intermediate filament patterns during development and in damaged tissueQ67694703
Podocytes in glomerulus of rat kidney express a characteristic 44 KD proteinQ67921236
Immunocytochemical localization of Na-K-ATPase alpha- and gamma-subunits in rat kidneyQ74364171
Wilms' tumour may also develop from impaired differentiation of the ureteric budQ80666866
Canonical WNT signalling determines lineage specificity in Wilms tumourQ83173652
Lin28 sustains early renal progenitors and induces Wilms tumorQ28511047
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital systemQ28511083
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Large-scale identification of genes implicated in kidney glomerulus development and functionQ28586898
Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney developmentQ28587889
The ECM protein nephronectin promotes kidney development via integrin alpha8beta1-mediated stimulation of Gdnf expressionQ28589474
Embryonic renal epithelia: induction, nephrogenesis, and cell differentiationQ33744636
Kidney morphogenesis: cellular and molecular regulationQ33855366
Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney developmentQ33904019
The GUDMAP database--an online resource for genitourinary researchQ33926410
Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulkQ33949184
Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylationQ34428960
Microdissecting the genetic events in nephrogenic rests and Wilms' tumor developmentQ35753374
Mammalian kidney development: principles, progress, and projectionsQ35902711
Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group StudyQ36200428
The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targetsQ36602158
Renal abnormalities and their developmental originQ36945522
Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo.Q36967093
Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesisQ37264929
Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumorQ37874427
GUDMAP: the genitourinary developmental molecular anatomy projectQ38514359
Ultrastructure and histogenesis of the renal tumors of childhood: an overviewQ39509552
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectnephroblastomaQ756289
P304page(s)e0186333
P577publication date2017-10-17
P1433published inPLOS OneQ564954
P1476titleThe developmental programme for genesis of the entire kidney is recapitulated in Wilms tumour
P478volume12

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