Parathyroid hormone-related protein overexpression protects goat mammary gland epithelial cells from calcium-sensing receptor activation-induced apoptosis

scientific article published on 30 September 2014

Parathyroid hormone-related protein overexpression protects goat mammary gland epithelial cells from calcium-sensing receptor activation-induced apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11033-014-3763-8
P698PubMed publication ID25266236

P2093author name stringHui Li
Qian Yu
Lihui Li
Huiling Zheng
Yongsen Sun
Xiaotong Yao
P2860cites workMutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidismQ24320383
Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactationQ24645591
Inhibitory effect of hepatocyte growth factor on cardiomyocytes apoptosis is partly related to reduced calcium sensing receptor expression during a model of simulated ischemia/reperfusionQ28572745
Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland developmentQ28585902
PTHrP Overexpression Increases Sensitivity of Breast Cancer Cells to Apo2L/TRAIL.Q31122542
Calcium-sensing receptor induces rat neonatal ventricular cardiomyocyte apoptosisQ33260643
Skeletal recovery after weaning does not require PTHrP.Q33817186
Calcium-sensing receptors induce apoptosis during simulated ischaemia-reperfusion in Buffalo rat liver cellsQ33938491
Parathyroid hormone-related peptide production and action in a myoepithelial cell line derived from normal human breastQ34356947
Increased PTHrP and Decreased Estrogens Alter Bone Turnover but Do Not Reproduce the Full Effects of Lactation on the SkeletonQ34392597
Role of the calcium-sensing receptor in cardiomyocyte apoptosis via the sarcoplasmic reticulum and mitochondrial death pathway in cardiac hypertrophy and heart failureQ34742338
The calcium-sensing receptor regulates mammary gland parathyroid hormone-related protein production and calcium transportQ36056698
Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cellsQ36861448
Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor.Q37438278
BRCA1 suppresses the expression of survivin and promotes sensitivity to paclitaxel through the calcium sensing receptor (CaSR) in human breast cancer cellsQ39597368
Activation of the calcium-sensing receptor by high calcium induced breast cancer cell proliferation and TRPC1 cation channel over-expression potentially through EGFR pathways.Q39866463
Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptorQ39872941
Calcium sensing receptor down-regulates malignant cell behavior and promotes chemosensitivity in human breast cancer cellsQ39911442
Parathyroid hormone-related protein (PTHrP) inhibits mitochondrial-dependent apoptosis through CK2.Q40143874
The calcium sensing receptor is directly involved in both osteoclast differentiation and apoptosisQ40213740
Intracrine PTHrP protects against serum starvation-induced apoptosis and regulates the cell cycle in MCF-7 breast cancer cellsQ40756696
Construction of recombinant adenoviruses carrying the optimal shRNA template against goat PTHrP and successful suppression of PTHrP expression in mammary epithelial cellsQ42267169
Extracellular calcium-sensing receptor expression and its potential role in regulating parathyroid hormone-related peptide secretion in human breast cancer cell linesQ42496898
ΔFosB regulates Ca²⁺ release and proliferation of goat mammary epithelial cellsQ42660624
Calcium-sensing receptor activation contributed to apoptosis stimulates TRPC6 channel in rat neonatal ventricular myocytesQ43122085
The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis.Q44526270
Low Estrogen and High Parathyroid Hormone-Related Peptide Levels Contribute to Accelerated Bone Resorption and Bone Loss in Lactating MiceQ44590717
A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidismQ48069081
Activation of calcium-sensing receptor accelerates apoptosis in hyperplastic parathyroid cellsQ50085827
The calcium-sensing receptor regulates PTHrP production and calcium transport in the lactating mammary glandQ50094981
Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development.Q52141026
Role of Parathyroid Hormone-Related Protein in Tubulointerstitial Apoptosis and Fibrosis after Folic Acid-Induced NephrotoxicityQ61854931
A cloned Ca(2+)-sensing receptor: a mediator of direct effects of extracellular Ca2+ on renal function?Q71373655
Association of decreased calcium-sensing receptor expression with proliferation of parathyroid cells in secondary hyperparathyroidismQ73108204
Parathyroid hormone-related peptide and survival of patients with cancer and hypercalcemiaQ73739838
P433issue1
P921main subjectoverexpressionQ61643320
P304page(s)233-243
P577publication date2014-09-30
P1433published inMolecular Biology ReportsQ15752755
P1476titleParathyroid hormone-related protein overexpression protects goat mammary gland epithelial cells from calcium-sensing receptor activation-induced apoptosis
P478volume42

Reverse relations

cites work (P2860)
Q41112230Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein
Q38737740Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
Q99415054Understanding seasonal weight loss tolerance in dairy goats: a transcriptomics approach

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