Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial

scientific article published on 13 February 2013

Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(12)62177-1
P8608Fatcat IDrelease_xgdl6klfyre75ml24ve6crj4e4
P698PubMed publication ID23415013

P2093author name stringFreek W A Verheugt
Johannes C Kelder
Jurriën M ten Berg
Tom Adriaenssens
Marije M Vis
Mathias Vrolix
Jean-Paul Herrman
Willem J M Dewilde
Arnoud W van 't Hof
Antonius A C M Heestermans
Bart J G L De Smet
Jan G P Tijsen
Tom Oirbans
WOEST study investigators
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Contra: 'Antithrombotic therapy with warfarin, aspirin and clopidogrel is the recommended regimen in anticoagulated patients who present with an acute coronary syndrome and/or undergo percutaneous coronary interventions'. Not for everybodyQ79804186
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Safety and efficacy of aspirin, clopidogrel, and warfarin after coronary stent placement in patients with an indication for anticoagulationQ28167576
Meta-analysis of trials comparing oral anticoagulation and aspirin versus dual antiplatelet therapy after coronary stenting. Clues for the management of patients with an indication for long-term anticoagulation undergoing coronary stentingQ28183958
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An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigatorsQ28254763
Ticagrelor versus clopidogrel in patients with acute coronary syndromesQ29619002
A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.Q33504515
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Clinical end points in coronary stent trials: a case for standardized definitionsQ36807166
Anticoagulant and antiplatelet therapy use in 426 patients with atrial fibrillation undergoing percutaneous coronary intervention and stent implantation implications for bleeding risk and prognosisQ37092388
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Bleeding, blood transfusion, and increased mortality after percutaneous coronary intervention: implications for contemporary practiceQ37499351
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Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients: the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS).Q39479800
Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of CardiologyQ39734057
Design and rationale of the WOEST trial: What is the Optimal antiplatElet and anticoagulant therapy in patients with oral anticoagulation and coronary StenTing (WOEST).Q42637505
Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillationQ42908804
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).Q42923039
Duration of dual antiplatelet therapy after implantation of drug-eluting stents.Q43128835
Three-year survival following multivessel percutaneous coronary intervention with bare-metal or drug-eluting stents in unselected patientsQ44438496
Impact of "nuisance" bleeding on clopidogrel compliance in patients undergoing intracoronary drug-eluting stent implantation.Q46209759
P433issue9872
P407language of work or nameEnglishQ1860
P921main subjectaspirinQ18216
clopidogrelQ410237
anticoagulantQ215118
anticoagulationQ63279445
P304page(s)1107-1115
P577publication date2013-02-13
P1433published inThe LancetQ939416
P1476titleUse of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial
P478volume381

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Q47336250Oral anticoagulation therapy upon discharge in hospitalized patients with nonvalvular atrial fibrillation: a retrospective cohort study.
Q47304863Outcome of octogenarians with atrial fibrillation undergoing percutaneous coronary intervention: insights from the AFCAS registry.
Q41627417Outcomes and Prognostic Impact of Prophylactic Oral Anticoagulation in Anterior ST-Segment Elevation Myocardial Infarction Patients With Left Ventricular Dysfunction
Q40257227Outcomes following implantation of the Biolimus A9-eluting BioMatrix coronary stent: Primary analysis of the e-BioMatrix registry
Q89601115P2Y12 inhibitors with oral anticoagulation for percutaneous coronary intervention with atrial fibrillation: a systematic review and meta-analysis
Q38626782Pathophysiology of ST-segment elevation myocardial infarction: novel mechanisms and treatments.
Q44714275Patient selection for the implantation of a left atrial appendage occluder in primary and secondary prevention of cardioembolic stroke in atrial fibrillation
Q88195597Percutaneous Coronary Intervention in Patients Who Have an Indication for Oral Anticoagulation - an Evidence-based Approach to Antithrombotic Therapy
Q39002814Percutaneous Coronary Intervention of Complex Calcified Lesions With Drug-Coated Balloon After Rotational Atherectomy
Q38244025Percutaneous coronary intervention and atrial fibrillation: the triple therapy dilemma
Q50435881Percutaneous coronary intervention for three vessels of chronic total occlusion complicated with huge left ventricular thrombus
Q93055882Pharmacodynamic Effects of Vorapaxar in Patients With and Without Diabetes Mellitus: Results of the OPTIMUS-5 Study
Q26862694Pharmacotherapy in the cardiac catheterization laboratory: evolution and recent developments
Q38229559Platelet function and long-term antiplatelet therapy in women: is there a gender-specificity? A 'state-of-the-art' paper
Q50014351Platelet inhibition in patients with coronary, cerebral and peripheral macroangiopathy : What, when and how long?
Q41968141Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study
Q58792339Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis
Q38433830Post-PCI Antithrombotic Therapy in Patients Requiring Long-Term Anticoagulation
Q37040299Postdischarge Bleeding After Percutaneous Coronary Intervention and Subsequent Mortality and Myocardial Infarction: Insights From the HMO Research Network-Stent Registry
Q57154436Practical issues in clinical scenarios involving CKD patients requiring antithrombotic therapy in light of the 2017 ESC guideline recommendations
Q54580380Prasugrel or double-dose clopidogrel to overcome clopidogrel low-response--the TAILOR (Thrombocytes And IndividuaLization of ORal antiplatelet therapy in percutaneous coronary intervention) randomized trial.
Q53249162Preference for oral anticoagulation therapy for patients with atrial fibrillation in Europe in different clinical situations: results of the European Heart Rhythm Association Survey.
Q91800605Prevalence of drug-drug interaction in atrial fibrillation patients based on a large claims data
Q26801820Preventing bleeding and thromboembolic complications in atrial fibrillation patients undergoing surgery
Q46549519Prevention of Bleeding in Patients With Atrial Fibrillation Undergoing PCI (PIONEER): Three May End Up Being a Crowd.
Q92896971Previous Antithrombotic Therapy, Particularly Anticoagulant, Is Associated with Unfavorable Outcomes in Patients with Primary Spontaneous Intracerebral Hemorrhage Receiving Craniotomy: A Nationwide Population-Based Cohort Study
Q87081666Primary PCI in dabigatran-treated patient: is transradial approach and bivalirudin infusion a safe and effective therapeutic option?
Q44282782Primary percutaneous coronary intervention and bleeding risk in the era of drug-eluting stent: a long-term cohort study.
Q41073197Primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction in a patient taking dabigatran for chronic anticoagulation
Q49687467Prognostic Value of Ankle-Brachial Index in Patients Undergoing Percutaneous Coronary Intervention: In-Hospital and 1-Year Outcomes From the SHINANO Registry
Q35821319Proteins interacting with the 26S proteasome
Q57462908Radiofrequency catheter ablation prior to percutaneous coronary intervention in patients with atrial fibrillation coexisting with stable coronary artery disease: a single-center pilot study
Q94476070Rationale and design of a prospective multi-center randomized trial of EARLY treatment by rivaroxaban versus warfarin in ST-segment elevation MYOcardial infarction with Left Ventricular Thrombus (EARLY-MYO-LVT trial)
Q88085870Real-world antithrombotic therapies and clinical outcomes after second-generation drug-eluting stent implantation in patients with atrial fibrillation: a multi-center cohort study
Q35626702Recent advances in the diagnosis and treatment of acute myocardial infarction
Q26862897Recent advances in treatment of acute coronary syndromes
Q30544234Recurrent intraventricular thrombus six months after ST-elevation myocardial infarction in a diabetic man: a case report
Q58110174Relationship of Left Ventricular Thrombus Formation and Adverse Outcomes in Acute Anterior Myocardial Infarction in Patients Treated with Primary Percutaneous Coronary Intervention
Q37390016Resolution of left ventricular postinfarction thrombi in patients undergoing percutaneous coronary intervention using rivaroxaban in addition to dual antiplatelet therapy.
Q38201161Revascularization strategies for patients with stable coronary artery disease.
Q26776254Review of the top 5 cardiology studies of 2013-14
Q39273301Risk and Benefits of Triple Therapy in Patients Undergoing Coronary Stent Implantation Requiring Oral Anticoagulation: A Meta-Analysis of 16 Studies
Q58715507Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study
Q38398587Risks and benefits of triple oral anti-thrombotic therapies after acute coronary syndromes and percutaneous coronary intervention
Q26825230Rivaroxaban in patients with a recent acute coronary syndrome event: integration of trial findings into clinical practice
Q38188899Rivaroxaban: a review of its use in acute coronary syndromes
Q38171396Role of novel and emerging oral anticoagulants for secondary prevention of acute coronary syndromes
Q37461045STENTING STRATEGY AND FOLLOW-UP RESULTS OF MULTI-CENTER REGISTRY IN FUKUSHIMA CITY FOR LEFT MAIN CORONARY ARTERY DISEASE: BARE METAL STENT VERSUS DRUG-ELUTING STENT.
Q55113397Safety and efficacy of dual vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of randomized clinical trials.
Q51760655Scientific foundation and possible implications for practice of the Minimizing Adverse Haemorrhagic Events by Transradial Access Site andSystemic Implementation of AngioX (MATRIX) trial.
Q38173148Secondary stroke prevention
Q53076603Selection of Warfarin or One of the New Oral Antithrombotic Agents for Long-Term Prevention of Stroke among Persons with Atrial Fibrillation.
Q37681956Simple and rapid assay for effect of the new oral anticoagulant (NOAC) rivaroxaban: preliminary results support further tests with all NOACs
Q53405663Solving the Issue of Restenosis After Stenting of Intracranial Stenoses: Experience with Two Thin-Strut Drug-Eluting Stents (DES)-Taxus Element™ and Resolute Integrity™.
Q92612170Statement on Antiplatelet Agents and Anticoagulants in Cardiology - 2019
Q92605110Status of international normalized ratio control and treatment patterns in patients with nonvalvular atrial fibrillation taking vitamin K antagonist with or without antiplatelet therapy: Results from KORAFII registry
Q26785321Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Grüntzig Lecture ESC 2014
Q38217692Strategies to reduce bleeding risk in acute coronary syndromes and percutaneous coronary intervention: new and emerging pharmacotherapeutic considerations.
Q38268827Stroke after transcatheter aortic valve replacement: incidence, risk factors, prognosis, and preventive strategies.
Q35962795Subtle renal dysfunction and bleeding risk in atrial fibrillation: symmetric dimethylarginine predicts HAS-BLED score
Q87479910Successful resolution of a left ventricular thrombus with apixaban treatment following acute myocardial infarction
Q38781617Targeting thrombin long-term after an acute coronary syndrome: Opportunities and challenges
Q91158866Temporal trends in prevalence and outcomes of atrial fibrillation in patients undergoing percutaneous coronary intervention
Q36396649The Indian consensus guidance on stroke prevention in atrial fibrillation: An emphasis on practical use of nonvitamin K oral anticoagulants
Q90429817The Management of Combined Antithrombotic Therapy in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Particularly Complex Challenge, Especially in the Elderly
Q37328158The effect of a dual or a triple antithrombotic therapy with apixaban on thrombus formation in vivo and in an ex vivo perfusion chamber model: An open-label, controlled, sequential study.
Q92723640The efficacy and safety of Shenzhu Guanxin Recipe Granules for the treatment of patients with coronary artery disease: protocol for a double-blind, randomized controlled trial
Q38688877The future of atrial fibrillation management: integrated care and stratified therapy
Q53191924The importance of endothelium-derived mediators to the efficacy of dual anti-platelet therapy.
Q92267268The myth of 'stable' coronary artery disease
Q38247892The optimal management of anti-thrombotic therapy after valve replacement: certainties and uncertainties
Q47865745The quest for safer antithrombotic treatment regimens in patients with coronary artery disease: new strategies and paradigm shifts
Q30234909The risk of bleeding with the use of antiplatelet agents for the treatment of cardiovascular disease
Q42180636The safety and efficacy of oral anticoagulants with dual versus single antiplatelet therapy in patients after percutaneous coronary intervention: A meta-analysis
Q26830164The year in atherothrombosis
Q47903684Thrombo-embolic prevention after transcatheter aortic valve implantation
Q64105469Thromboembolic and Bleeding Complications in Transcatheter Aortic Valve Implantation: Insights on Mechanisms, Prophylaxis and Therapy
Q50012336Thromboembolic and bleeding risk management in elderly patients: a case report.
Q38154611Ticagrelor for acute coronary syndromes
Q50986493Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression.
Q38557198Ticagrelor, prasugrel, or clopidogrel in ST-segment elevation myocardial infarction: which one to choose?
Q94562701Ticagrelor: A safe option as part of triple therapy?
Q52583885Time trends in antithrombotic management of patients with atrial fibrillation treated with coronary stents: Results from TALENT-AF (The internAtionaL stENT - Atrial Fibrillation study) multicenter registry.
Q54138570To neither bleed nor clot: That is the question.
Q91873263Towards appropriate polypharmacy in older cardiovascular patients: How many medications do I have to take?
Q26866350Treatment and prevention of gastrointestinal bleeding in patients receiving antiplatelet therapy
Q49990585Treatment of gastrointestinal bleeding with idarucizumab in a patient receiving dabigatran
Q92652445Trial Sequential Analysis Comparing Bleeding and Major Adverse Cardiovascular Events in Patients with Atrial Fibrillation and Acute Coronary Syndrome on Dual versus Triple Therapy
Q50852615Triple Antithrombotic Therapy With Aspirin, P2Y12 Inhibitor, and Warfarin After Percutaneous Coronary Intervention: An Evaluation of Prasugrel or Ticagrelor Versus Clopidogrel.
Q31001917Triple Antithrombotic Therapy after Percutaneous Coronary Intervention (PCI) in Patients with Indication for Oral Anticoagulation: Data from a Single Center Registry
Q48039374Triple Antithrombotic Therapy and Outcomes in Post-PCI Patients Undergoing Non-cardiac Surgery
Q48744990Triple Antithrombotic Therapy in Atrial Fibrillation Patients Undergoing PCI: a Fading Role
Q51805253Triple Therapy Versus Dual Antiplatelet Therapy for Patients with Atrial Fibrillation and Acute Coronary Syndromes: A Systematic Literature Review.
Q89397561Triple Therapy: When, if Ever?
Q42216679Triple antithrombotic therapy for atrial fibrillation and coronary stents
Q41011418Triple antithrombotic therapy in patients undergoing percutaneous coronary intervention: balancing between ischemia and bleeding
Q39193524Triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention: a viewpoint
Q38123126Triple oral antithrombotic therapy in atrial fibrillation and coronary artery stenting.
Q60301382Triple therapy after PCI - Warfarin treatment quality and bleeding risk
Q38543313Triple therapy for percutaneous coronary intervention in atrial fibrillation: standard of care, or a nightmare soon to end?
Q90644485Triple therapy in patients with atrial fibrillation and acute coronary syndrome or percutaneous coronary intervention/stenting
Q42360039Triple troubles selecting optimal therapy for atrial fibrillation patients undergoing percutaneous coronary interventions
Q49982021Trithérapie antithrombotique pour la fibrillation auriculaire et les endoprothèses coronariennes
Q39135634Unmet Needs in Anticoagulant Therapy: Potential Role of Rivaroxaban
Q90529438Update on Antithrombotic Therapy after Percutaneous Coronary Intervention
Q38556885Update on antithrombotic therapy after percutaneous coronary revascularisation
Q47789803Update on the use of direct oral anticoagulants for the prevention and treatment of thromboembolism
Q97421102Updated overview of evidence on optimal antithrombotic therapy in patients with atrial fibrillation undergoing percutanous coronary intervention
Q37536810Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry
Q35542784Use of Anticoagulants and Antiplatelet Agents in Stable Outpatients with Coronary Artery Disease and Atrial Fibrillation. International CLARIFY Registry
Q37434813Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention
Q45975657Use of Dual Antiplatelet Therapy and Patient Outcomes in Those Undergoing Percutaneous Coronary Intervention: The ROCKET AF Trial.
Q38496232Use of Non-Vitamin K Antagonist Oral Anticoagulants in Special Patient Populations with Nonvalvular Atrial Fibrillation: A Review of the Literature and Application to Clinical Practice
Q57818803Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation
Q60949999Use of direct oral anticoagulants in the treatment of left ventricular thrombi: A tertiary center experience and review of the literature
Q90018927Use of oral anticoagulants in complex clinical situations with atrial fibrillation
Q38941684Use of rivaroxaban in patients with stroke
Q55364273Vasodilator-stimulated phosphoprotein-guided Clopidogrel maintenance therapy reduces cardiovascular events in atrial fibrillation patients requiring anticoagulation therapy and scheduled for percutaneous coronary intervention: a prospective cohort s
Q47884992Vessel tree tracking in angiographic sequences
Q50793412Viewpoint: a proposal for a simple algorithm for managing oral anticoagulation and antiplatelet therapy in patients with non-valvular atrial fibrillation and coronary stents.
Q91759926Vitamin K antagonist vs direct oral anticoagulants with antiplatelet therapy in dual or triple therapy after percutaneous coronary intervention or acute coronary syndrome in atrial fibrillation: Meta-analysis of randomized controlled trials
Q86892134Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation
Q90397785When to withhold oral anticoagulation in atrial fibrillation - an overview of frequent clinical discussion topics
Q87479971[Antiplatelet therapy and anticoagulation in acute coronary syndrome: current evidence]
Q85841188[Antithrombotic therapy and atrial fibrillation. Dual or triple therapy after acute coronary syndrome and stent?]
Q86643067[ESC guidelines 2015. Non-ST-elevation acute coronary syndrome]
Q51276277[Knowledge of guidelines for anticoagulation management of patients with atrial fibrillation].
Q50875552[Management of acute coronary syndrome without ST-segment elevation].
Q86039476[Management of acute myocardial infarction with ST-segment elevation: Update 2013]
Q87307668[Medicinal treatment of atrial fibrillation in special situations]
Q53535820[Non-vitamin K dependent oral anticoagulants : What is important in intensive care medicine].
Q89623293[Platelet inhibition in elderly patients]

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