Pharmacokinetics of rec-hirudin in healthy volunteers after intravenous administration

scientific article published on April 1994

Pharmacokinetics of rec-hirudin in healthy volunteers after intravenous administration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/BF02353540
P698PubMed publication ID7815310

P2093author name stringJ M Cardot
G Y Lefèvre
J A Godbillon
P2860cites workPharmacokinetics of HirudinQ36917034
The comeback of hirudin--an old-established anticoagulant agentQ38192900
Biology of recombinant hirudin (CGP 39393): a new prospect in the treatment of thrombosisQ38735182
A hirudin catching ELISA for quantitating the anticoagulant in biological fluidsQ41974875
Pharmacological survey of recombinant hirudinQ48101571
Pharmacokinetics, effect on clotting tests and assessment of the immunogenic potential of hirudin after a single subcutaneous or intravenous bolus administration in man.Q52423429
Pharmacokinetics and pharmacodynamics of hirudin in man after single subcutaneous and intravenous bolus administration.Q52426744
Pharmacokinetics and anticoagulant effect of hirudin in man.Q52431805
Clinical pharmacology of recombinant hirudinQ67976036
Clinico-pharmacological studies with recombinant hirudinQ68026562
Effect of heparin, hirudin, and a synthetic thrombin inhibitor on antithrombin III in thrombin-induced disseminated intravascular coagulation in ratsQ68536268
Pharmacological studies on the antithrombotic action of hirudin in experimental animalsQ70439861
Clinical pharmacology of intravenously administered recombinant desulfatohirudin (CGP 39393) in healthy volunteersQ71599934
P433issue2
P921main subjectpharmacokineticsQ323936
hirudinQ386715
P304page(s)147-156
P577publication date1994-04-01
P1433published inJournal of Pharmacokinetics and PharmacodynamicsQ15766045
P1476titlePharmacokinetics of rec-hirudin in healthy volunteers after intravenous administration
P478volume22

Reverse relations

cites work (P2860)
Q73500562Characterization of C-terminal-truncated urinary metabolites of a recombinant hirudin in rats
Q34059396Desirudin: a review of its use in the management of thrombotic disorders
Q73562536Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin
Q44323022Effects of ximelagatran, an oral direct thrombin inhibitor, r-hirudin and enoxaparin on thrombin generation and platelet activation in healthy male subjects.
Q38410604Pharmacology and controlled release of hirudin for cardiovascular disorders

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