Anti-proliferative effect of rosiglitazone on angiotensin II-induced vascular smooth muscle cell proliferation is mediated by the mTOR pathway.

scientific article published on March 2012

Anti-proliferative effect of rosiglitazone on angiotensin II-induced vascular smooth muscle cell proliferation is mediated by the mTOR pathway. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/CBI20100524
P698PubMed publication ID22050182

P50authorYangsoo JangQ59695831
P2093author name stringKi-Chul Hwang
Min-Ji Cha
Jung-Sun Kim
Il-Kwon Kim
Eunmi Choi
Onju Ham
Byeong-Wook Song
Soyeon Lim
Heesang Song
Se-Yeon Lee
P2860cites workThe mechanisms of action of PPARsQ28216953
PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1Q28578260
ANG II type 2 receptor regulates smooth muscle growth and force generation in late fetal mouse developmentQ30434317
Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.Q34180196
The renin-angiotensin system and vascular hypertrophyQ34400269
Thiazolidinedione regulation of smooth muscle cell proliferationQ35609211
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular systemQ36548154
Involvement of connexin 43 in angiotensin II-induced migration and proliferation of saphenous vein smooth muscle cells via the MAPK-AP-1 signaling pathwayQ37395007
Akt is a major downstream target of PI3-kinase involved in angiotensin II-induced proliferationQ40665812
Troglitazone inhibits angiotensin II-induced extracellular signal-regulated kinase 1/2 nuclear translocation and activation in vascular smooth muscle cellsQ41676053
The inhibition of insulin-stimulated proliferation of vascular smooth muscle cells by rosiglitazone is mediated by the Akt-mTOR-P70S6K pathwayQ43211170
Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formationQ44271062
Phosphatidylinositol 3-kinase in angiotensin II-induced hypertrophy of vascular smooth muscle cellsQ44614710
PPAR(gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic miceQ44743365
ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cellsQ45022808
Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes.Q45124478
PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.Q46006542
Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophyQ46564947
Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteriesQ46618559
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cellsQ46846204
Peroxisome proliferator-activated receptor gamma regulates angiotensin II-stimulated phosphatidylinositol 3-kinase and mitogen-activated protein kinase in blood vessels in vivoQ46847915
Antiproliferative mechanisms of raxofelast (IRFI-016) in H2O2-stimulated rat aortic smooth muscle cellsQ47241376
Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells - role of PPAR-gamma in vascular fibrosis.Q53590760
P433issue3
P921main subject(RS)-rosiglitazoneQ424771
P304page(s)305-310
P577publication date2012-03-01
P1433published inCell Biology InternationalQ1254690
P1476titleAnti-proliferative effect of rosiglitazone on angiotensin II-induced vascular smooth muscle cell proliferation is mediated by the mTOR pathway
P478volume36

Reverse relations

cites work (P2860)
Q36926148Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions
Q50033960Gliclazide, a KATP channel blocker, inhibits vascular smooth muscle cell proliferation through the CaMKKβ-AMPK pathway
Q53281676MicroRNA-365 inhibits the proliferation of vascular smooth muscle cells by targeting cyclin D1.
Q40458029MicroRNA-761 inhibits Angiotensin II-induced vascular smooth muscle cell proliferation and migration by targeting mammalian target of rapamycin.
Q35884929Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive rats
Q37510124Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Q53003922Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell.
Q44629243Role of Akt signaling pathway in delayed cerebral vasospasm after subarachnoid hemorrhage in rats
Q27309387Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells

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