Adjunct therapy for sepsis: how early?

scientific article published on September 2010

Adjunct therapy for sepsis: how early? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11908-010-0123-2
P698PubMed publication ID21308518

P50authorDjillali AnnaneQ30004548
P2860cites workPhysiological-dose steroid therapy in sepsis [ISRCTN36253388]Q21195121
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotectiveQ24293646
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careQ27860820
Hydrocortisone therapy for patients with septic shockQ28264225
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care MedicineQ28280888
Efficacy and safety of recombinant human activated protein C for severe sepsisQ29547839
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008Q29615602
Corticosteroids: way upstreamQ33738920
Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center studyQ33861751
A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropinQ33891791
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shockQ34145159
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of deathQ34455153
Reversal of late septic shock with supraphysiologic doses of hydrocortisoneQ34465500
Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shockQ34466069
Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsisQ34999600
Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.Q35831218
Glucocorticoids in the treatment of severe sepsis and septic shockQ36262817
Randomized trials stopped early for benefit: a systematic reviewQ36303650
Recombinant human activated protein C: current insights into its mechanism of actionQ37082968
Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.Q37513002
Activated protein C for sepsisQ37665097
Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trialQ38376133
Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.Q40235280
Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial.Q40453111
Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature.Q40460082
Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptorQ40657744
Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1.Q44315236
Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytesQ50281724
Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment*Q64126934
Inhibition of fibrinolytic activity in-vivo by dexamethasone is counterbalanced by an inhibition of platelet aggregationQ68030002
Survival of primates in lethal septic shock following delayed treatment with steroidQ70159244
GLucocorticoids inhibit the generation of leukocyte procoagulant (tissue factor) activityQ70473760
Effect of glucocorticosteroids on some coagulation testsQ71622448
Impairment of fibrinolytic potential in long-term steroid treatment after heart transplantationQ73987371
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsisQ78836710
Prophylactic heparin in patients with severe sepsis treated with drotrecogin alfa (activated)Q80447715
Septic shockQ81245367
Early dexamethasone treatment for septic shock patients: a prospective randomized clinical trialQ81574798
P433issue5
P921main subjectsepsisQ183134
P304page(s)361-367
P577publication date2010-09-01
P1433published inCurrent infectious disease reportsQ26842136
P1476titleAdjunct therapy for sepsis: how early?
P478volume12