Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism

scientific article published on 31 March 2016

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.705541
P932PMC publication ID4882453
P698PubMed publication ID27036938

P50authorRudolf ZechnerQ2174164
Ulrike TaschlerQ38328676
Robert ZimmermannQ38328715
Sepp D KohlweinQ40322959
Christoph HeierQ42757589
Monika ObererQ42757594
Thomas O EichmannQ56948167
P2093author name stringHeimo Wolinski
Maja Radulovic
Philip Aschauer
Susanne Grond
P2860cites workBrain monoglyceride lipase participating in endocannabinoid inactivationQ24533828
Alcohol metabolismQ24621827
Microsomal preparations from plant and yeast acylate free fatty acids without prior activation to acyl-thioestersQ79783691
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The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity.Q27931159
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Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeastQ27931759
YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiaeQ27932920
The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysisQ27933795
Tgl4p and Tgl5p, two triacylglycerol lipases of the yeast Saccharomyces cerevisiae are localized to lipid particlesQ27934410
High confidence proteomic analysis of yeast LDs identifies additional droplet proteins and reveals connections to dolichol synthesis and sterol acetylation.Q27934676
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Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthaseQ28269415
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Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammationQ35645037
Postnatal ethanol exposure alters levels of 2-arachidonylglycerol-metabolizing enzymes and pharmacological inhibition of monoacylglycerol lipase does not cause neurodegeneration in neonatal mice.Q35815626
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The yeast enzyme Eht1 is an octanoyl-CoA:ethanol acyltransferase that also functions as a thioesteraseQ43088569
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Fatty acid ethyl esters in hair as markers of alcohol consumption. Segmental hair analysis of alcoholics, social drinkers, and teetotalersQ43806579
The lipid droplet enzyme Tgl1p hydrolyzes both steryl esters and triglycerides in the yeast, Saccharomyces cerevisiaeQ46515916
Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesisQ46985842
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A role for seipin in lipid droplet dynamics and inheritance in yeast.Q50669487
VMA11 and VMA16 encode second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase.Q52523934
Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcoholQ61771883
Limited palmitoyl-CoA penetration into microsomal vesicles as evidenced by a highly latent ethanol acyltransferase activityQ67393402
The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipaseQ67982906
Pancreatic cholesterol esterases. 2. Purification and characterization of human pancreatic fatty acid ethyl ester synthaseQ68817211
Purification to homogeneity and characterization of major fatty acid ethyl ester synthase from human myocardiumQ69406226
Synthesis of fatty acid esters of short-chain alcohols by an acyltransferase in rat liver microsomesQ69517084
Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerolQ70026539
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Fatty acid ethyl esters in the blood as markers for ethanol intakeQ71582104
Purification and characterization of human heart fatty acid ethyl ester synthase/carboxylesteraseQ71741504
Fatty acid ethyl esters decrease human hepatoblastoma cell proliferation and protein synthesisQ72460827
Formation of fatty acid ethyl esters in rat liver microsomes. Evidence for a key role for acyl-CoA: ethanol O-acyltransferaseQ77892894
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)11865-11875
P577publication date2016-03-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleMonoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
P478volume291

Reverse relations

cites work (P2860)
Q93166420Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders
Q39141240Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling
Q37664248Nonoxidative ethanol metabolism in humans-from biomarkers to bioactive lipids

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