| scholarly article | Q13442814 |
| P50 | author | Mustafa Sahin | Q42875603 |
| Christian C. Dibble | Q58682439 | ||
| P2093 | author name string | Brendan D Manning | |
| Alex I Lipovsky | |||
| Hui H Zhang | |||
| P2860 | cites work | GSK3 inhibitors: development and therapeutic potential | Q35790372 |
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| P433 | issue | 2 | |
| P304 | page(s) | 185-197 | |
| P577 | publication date | 2006-10-01 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt. | |
| P478 | volume | 24 |
| Q35837163 | 4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL |
| Q24655791 | A complex interplay between Akt, TSC2 and the two mTOR complexes |
| Q40030572 | A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B. |
| Q35757839 | A pivotal role of GSK-3 in synaptic plasticity. |
| Q35191036 | AKT and TOR signaling set the pace of the circadian pacemaker |
| Q46141530 | AKT-ing out: SGK kinases come to the fore |
| Q24657857 | AKT/PKB signaling: navigating downstream |
| Q37309942 | AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling |
| Q98906856 | Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial-mesenchymal transition |
| Q64113311 | Abnormal glycogen storage in tuberous sclerosis complex caused by impairment of mTORC1-dependent and -independent signaling pathways |
| Q36089376 | Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo. |
| Q89441275 | Activation of WNT/β-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations |
| Q29615179 | Activation of a metabolic gene regulatory network downstream of mTOR complex 1 |
| Q34737936 | Activation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury |
| Q53190419 | Activation of mTORC1 in B Lymphocytes Promotes Osteoclast Formation via Regulation of β-Catenin and RANKL/OPG. |
| Q37372606 | Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype |
| Q35175103 | Adenovirus entry from the apical surface of polarized epithelia is facilitated by the host innate immune response |
| Q34150587 | Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease |
| Q28242180 | Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways |
| Q41644777 | Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. |
| Q91947139 | An expanding GSK3 network: implications for aging research |
| Q34374407 | BRAFV600E Negatively Regulates the AKT Pathway in Melanoma Cell Lines |
| Q47414450 | BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β. |
| Q41280277 | BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity. |
| Q38978483 | Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation |
| Q28116831 | Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis |
| Q92462879 | Blood feeding activates the vitellogenic stage of oogenesis in the mosquito Aedes aegypti through inhibition of glycogen synthase kinase 3 by the insulin and TOR pathways |
| Q51602035 | Brassinosteriod Insensitive 2 (BIN2) acts as a downstream effector of the Target of Rapamycin (TOR) signaling pathway to regulate photoautotrophic growth in Arabidopsis |
| Q90044328 | Broad regulation of gene isoform expression by Wnt signaling in cancer |
| Q41140239 | Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation |
| Q33718319 | Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway |
| Q38609949 | Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3. |
| Q89626907 | Chronic mTOR activation induces a degradative smooth muscle cell phenotype |
| Q38421077 | Comparative effects of whey protein versus L-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following resistance exercise |
| Q41891152 | Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation |
| Q35108092 | Convergence of the Mammalian Target of Rapamycin Complex 1- and Glycogen Synthase Kinase 3-β–Signaling Pathways Regulates the Innate Inflammatory Response |
| Q47820965 | Coordination between Differentially Regulated Circadian Clocks Generates Rhythmic Behavior |
| Q38834304 | Different interactomes for p70-S6K1 and p54-S6K2 revealed by proteomic analysis |
| Q41160745 | Downhill Running-Based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway without Concomitant Decrease of Inflammatory Proteins |
| Q37621011 | Drosophila Myc. |
| Q34032753 | Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo |
| Q48819008 | Exercise Prevents Amyloid-β-Induced Hippocampal Network Disruption by Inhibiting GSK3β Activation. |
| Q35014198 | Frontier of Epilepsy Research - mTOR signaling pathway |
| Q36228566 | GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy |
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| Q40004430 | GSK-3beta-dependent destabilization of cyclin D1 mediates replicational stress-induced arrest of cell cycle |
| Q21285144 | GSK-3β: A Bifunctional Role in Cell Death Pathways |
| Q37774552 | GSK3 signalling in neural development |
| Q92894369 | GSK3-CRMP2 signaling mediates axonal regeneration induced by Pten knockout |
| Q39357584 | GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy |
| Q33588024 | GSK3β, but not GSK3α, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mammalian target of rapamycin complex1. |
| Q38915241 | Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes |
| Q89568648 | Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution |
| Q38660834 | Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes |
| Q33710200 | Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death |
| Q34528331 | Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress |
| Q39950939 | Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells |
| Q37105335 | Glycogen synthase kinase-3 and mammalian target of rapamycin pathways contribute to DNA synthesis, cell cycle progression, and proliferation in human islets |
| Q42008987 | High expression of PP2A-Aα is associated with diapause induction during the photoperiod-sensitive stage of the cotton bollworm, Helicoverpa armigera |
| Q55269141 | Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells. |
| Q33707315 | Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice |
| Q40979448 | Improved antitumor effect of ionizing radiation in combination with rapamycin for treating nasopharyngeal carcinoma |
| Q40525689 | Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation |
| Q33316159 | Incorporating molecular tools into early-stage clinical trials |
| Q42452282 | Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition |
| Q33829976 | Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis |
| Q37711217 | Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. |
| Q33480974 | Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway |
| Q37613506 | Key factors in mTOR regulation. |
| Q43720833 | Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function |
| Q61796104 | MG132 protects against renal dysfunction by regulating Akt-mediated inflammation in diabetic nephropathy |
| Q54194891 | Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice |
| Q37943416 | Mammalian TOR signaling to the AGC kinases |
| Q35107703 | Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy |
| Q37828371 | Metabolism, migration and memory in cytotoxic T cells |
| Q27301246 | Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy |
| Q90359792 | Minocycline attenuates ethanol-induced cell death and microglial activation in the developing spinal cord |
| Q39707997 | Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation |
| Q59701095 | Modulating NRF2 in Disease: Timing Is Everything |
| Q49611838 | Modulation of GSK3β autoinhibition by Thr-7 and Thr-8. |
| Q42348037 | Molecular mechanism of circadian rhythmicity of seizures in temporal lobe epilepsy |
| Q34291633 | Myc Function in Drosophila |
| Q21092404 | NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas |
| Q37275182 | NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth |
| Q38310202 | O-GlcNAc: A Bittersweet Switch in Liver |
| Q91842202 | Pharmacologic and genetic approaches define human pancreatic β cell mitogenic targets of DYRK1A inhibitors |
| Q36324321 | Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients |
| Q38232871 | Phytohormone regulation of legume-rhizobia interactions |
| Q37051667 | Possible mechanisms of disease development in tuberous sclerosis |
| Q45965161 | Prophetic Granger Causality to infer gene regulatory networks. |
| Q37882868 | Protein Kinase C: The "Masters" of Calcium and Lipid |
| Q36917916 | Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins |
| Q36905652 | Protein kinase D2 contributes to TNF-α-induced epithelial mesenchymal transition and invasion via the PI3K/GSK-3β/β-catenin pathway in hepatocellular carcinoma |
| Q37789771 | Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations |
| Q33705425 | Rapamycin Is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate |
| Q41849700 | Rapamycin ameliorates inflammation and fibrosis in the early phase of cirrhotic portal hypertension in rats through inhibition of mTORC1 but not mTORC2. |
| Q36971030 | Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation |
| Q24336314 | Regulation and localization of ribosomal protein S6 kinase 1 isoforms |
| Q93161675 | Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin |
| Q38193259 | Regulation of Wnt/β-catenin signaling by posttranslational modifications |
| Q54493318 | Regulation of endothelial cell morphogenesis by the protein kinase D (PKD)/glycogen synthase kinase 3 (GSK3)β pathway |
| Q38034501 | Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases |
| Q35834072 | Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo |
| Q99214216 | Regulation of mTORC2 Signaling |
| Q57069571 | Research progress on signaling pathways in cirrhotic portal hypertension |
| Q58701699 | Resibufogenin suppresses transforming growth factor-β-activated kinase 1-mediated nuclear factor-κB activity through protein kinase C-dependent inhibition of glycogen synthase kinase 3 |
| Q36760689 | Role of PI3K-AKT-mTOR and Wnt Signaling Pathways in Transition of G1-S Phase of Cell Cycle in Cancer Cells. |
| Q39900962 | S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation |
| Q55026570 | Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension. |
| Q59812530 | Semaphorin 3F and Netrin-1: The Novel Function as a Regulator of Tumor Microenvironment |
| Q43231611 | Smad3-dependent and -independent pathways are involved in peritoneal membrane injury |
| Q34285136 | Speed control: cogs and gears that drive the circadian clock |
| Q88576211 | Stimulation-dependent remodeling of the corticospinal tract requires reactivation of growth-promoting developmental signaling pathways |
| Q40977960 | Stress and inflammatory gene networks in bovine liver are altered by plane of dietary energy during late pregnancy. |
| Q37575390 | Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids |
| Q34786821 | TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. |
| Q27929989 | TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases |
| Q52365700 | TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β. |
| Q30505171 | Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation |
| Q34828662 | The PTEN-PI3K pathway: of feedbacks and cross-talks |
| Q38117148 | The Paradox of Akt-mTOR Interactions. |
| Q38259593 | The Role of Glycogen Synthase Kinase 3 Beta in Neuroinflammation and Pain |
| Q33737444 | The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival |
| Q41832120 | The TSC-mTOR pathway regulates macrophage polarization |
| Q36710799 | The TSC1-TSC2 complex is required for proper activation of mTOR complex 2 |
| Q24645204 | The TSC1-TSC2 complex: a molecular switchboard controlling cell growth |
| Q35671970 | The Yeast GSK-3 Homologue Mck1 Is a Key Controller of Quiescence Entry and Chronological Lifespan. |
| Q43002035 | The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration. |
| Q34308263 | The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation |
| Q36971815 | The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid |
| Q29617465 | The nuts and bolts of AGC protein kinases |
| Q46147838 | The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. |
| Q36729436 | The ribosomal protein S6 in renal cell carcinoma: functional relevance and potential as biomarker |
| Q92665751 | The role of aurora A and polo-like kinases in high-risk lymphomas |
| Q39102576 | The serine-threonine kinase p90RSK is a new target of enzastaurin in follicular lymphoma cells |
| Q36959923 | Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action |
| Q36500453 | Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins. |
| Q33602544 | Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis |
| Q37215418 | Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner |
| Q37545014 | Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. |
| Q42558518 | Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization |
| Q28568279 | Uniaxial stretch-induced regulation of mitogen-activated protein kinase, Akt and p70 S6 kinase in the ageing Fischer 344 x Brown Norway rat aorta |
| Q83431808 | Visfatin exerts angiogenic effects on human umbilical vein endothelial cells through the mTOR signaling pathway |
| Q34752403 | WIPI1 Coordinates Melanogenic Gene Transcription and Melanosome Formation via TORC1 Inhibition |
| Q30489319 | Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway |
| Q37015808 | dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth |
| Q49141547 | mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells |
| Q54977263 | mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation. |
| Q37134416 | mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability |
| Q41840986 | mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition |
| Q38091510 | mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB |
| Q28583302 | mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway |
| Q57295897 | mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level |
| Q42813304 | mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. |
| Q36731316 | pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation |
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