Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases

scientific article published on March 1996

Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.132.6.1037
P932PMC publication ID2120756
P698PubMed publication ID8601583
P5875ResearchGate publication ID278392913

P50authorGregory P. DowneyQ40321406
P2093author name stringFukushima T
Grinstein S
Orlowski J
Waddell TK
Goss GG
P2860cites workMolecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporterQ24306376
Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophilsQ24309479
Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchangerQ24561386
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseQ26778460
Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kDQ28236680
Tyrosine phosphorylation of phospholipase C-gamma 2 is involved in the activation of phosphoinositide hydrolysis by Fc receptors in human neutrophilsQ28633812
Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteinsQ31154629
Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblastsQ33862274
Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox functionQ34141124
FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinaseQ34229526
The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspectsQ34507357
Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharideQ35835581
Immune complex-stimulated neutrophil LTB4 production is dependent on beta 2 integrinsQ36233153
The role of membrane receptors for C3b and C3d in phagocytosisQ36335168
Control of intracellular pH and growth by fibronectin in capillary endothelial cellsQ36383431
Regulation of intracellular pH in human neutrophilsQ36409330
Phorbol ester-induced actin assembly in neutrophils: role of protein kinase CQ36530882
CR3 (Mac-1, alpha M beta 2, CD11b/CD18) and Fc gamma RIII cooperate in generation of a neutrophil respiratory burst: requirement for Fc gamma RIII and tyrosine phosphorylationQ36534850
The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing"Q36901232
Proton secretion by stimulated neutrophils. Significance of hexose monophosphate shunt activity as source of electrons and protons for the respiratory burstQ36992918
A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pHQ37561464
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shapeQ37588910
Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferationQ38263958
Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situQ39251346
Activation of the neutrophil.Q39606112
Transport of H+ and of ionic weak acids and basesQ40149858
Fc receptor-mediated signal transductionQ40727590
Intracellular pH modulates the generation of superoxide radicals by human neutrophilsQ40920330
Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilamentsQ41182472
Two mechanisms for IgG Fc-receptor-mediated phagocytosis by human neutrophilsQ41185178
Receptor-mediated actin assembly in electropermeabilized neutrophils: role of intracellular pH.Q41307093
The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sitesQ41468509
Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.Q41516472
Multiple cytokines induce the tyrosine phosphorylation of Shc and its association with Grb2 in hemopoietic cellsQ41521070
KIM185, a monoclonal antibody to CD18 which induces a change in the conformation of CD18 and promotes both LFA‐1‐ and CR3‐dependent adhesionQ41532475
Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2)Q41548156
Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3).Q41683481
Inhibition of chemotactic factor-activated Na+/H+ exchange in human neutrophils by analogues of amiloride: structure-activity relationships in the amiloride seriesQ41936717
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinaseQ41974543
Calcium signaling capacity of the integrin on human neutrophilsQ42464509
Brush-border tyrosine phosphorylation stimulates ileal neutral NaCl absorption and brush-border Na(+)-H+ exchangeQ42500717
Phosphorylation of Na(+)-H+ antiporter is not stimulated by phorbol ester and acidification in granulocytic HL-60 cellsQ42507879
Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils.Q42832820
Isolation and characterization of platelet membranes prepared by free flow electrophoresisQ43688014
Phosphatidylinositol-linked FcRIII mediates exocytosis of neutrophil granule proteins, but does not mediate initiation of the respiratory burstQ44637481
Monoclonal antibody to human IgG Fc receptors. Cross-linking of receptors induces lysosomal enzyme release and superoxide generation by neutrophilsQ45054115
Evidence for the involvement of tyrosine kinases in the locomotory responses of human neutrophilsQ45115862
Isolation of Full-Length RNA Templates for Reverse Transcription from Tissues Rich in RNase and ProteoglycansQ46019977
Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.Q48116251
Phorbol ester-induced changes in cytoplasmic Ca2+ in human neutrophils. Involvement of a pertussis toxin-sensitive G protein.Q54132791
Signal transduction by neutrophil immunoglobulin G Fc receptors. Dissociation of intracytoplasmic calcium concentration rise from inositol 1,4,5-trisphosphateQ54273778
Characterization of the amiloride-sensitive Na+-H+ antiport of human neutrophils.Q54432801
Multiple integrins share the ability to induce elevation of intracellular pHQ57446994
Differential roles of Fc gamma RII and Fc gamma RIII in immune complex stimulation of human neutrophilsQ67862194
Activation of vacuolar-type proton pumps by protein kinase C. Role in neutrophil pH regulationQ67864795
Activation of the Na+/H+ antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanismQ67864832
Chemoattractant-induced tyrosine phosphorylation and activation of microtubule-associated protein kinase in human neutrophilsQ67899134
Evidence for cross-regulation of Fc gamma RIIIB (CD16) receptor-mediated signaling by Fc gamma RII (CD32) expressed on polymorphonuclear neutrophilsQ67927324
Platelet-activating factor induces tyrosine phosphorylation in human neutrophilsQ67985293
The 40-kDa Fc gamma receptor (FcRII) on human neutrophils is essential for the IgG-induced respiratory burst and IgG-induced phagocytosisQ69334894
Natural killer cell and granulocyte Fc gamma receptor III (CD16) differ in membrane anchor and signal transductionQ69358772
Chemotactic factor-induced activation of Na+/H+ exchange in human neutrophils. I. Sodium fluxesQ70105798
Cytoplasmic pH regulation in normal and abnormal neutrophils. Role of superoxide generation and Na+/H+ exchangeQ70118761
Volume changes in activated human neutrophils: the role of Na+/H+ exchangeQ70142475
Cytoplasmic pH regulation in activated human neutrophils: effects of adenosine and pertussis toxin on Na+/H+ exchange and metabolic acidificationQ70156515
Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchangerQ70468477
In human neutrophils the binding to immunocomplexes induces the tyrosine phosphorylation of Fc gamma RII but this phosphorylation is not an essential signal for Fc-mediated phagocytosisQ71625532
Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectinQ71634365
The role of cyclic AMP, calcium and filamentous actin in adenosine modulation of Fc receptor-mediated phagocytosis in human neutrophilsQ72062142
Tyrosine phosphorylation and intracellular alkalinization are early events in human neutrophils stimulated by tumor necrosis factor, granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factorQ72068968
Cocapping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fc gamma receptor III on human neutrophils. Possible role of lectin-like interactionsQ72073834
Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferationQ72196604
Lectin-like inhibition of immune complex receptor-mediated stimulation of neutrophils. Effects on cytosolic calcium release and superoxide productionQ72217305
Isolation and characterization of gelatinase granules from human neutrophilsQ72282828
Mutation of calmodulin-binding site renders the Na+/H+ exchanger (NHE1) highly H(+)-sensitive and Ca2+ regulation-defectiveQ72403727
Formation of inositol (1,4,5) trisphosphate and increase of cytosolic Ca2+ mediated by Fc receptors in human neutrophilsQ72632774
Neutrophils increase volume during migration in vivo and in vitroQ72734127
Signaling properties of CR3 (CD11b/CD18) and CR1 (CD35) in relation to phagocytosis of complement-opsonized particlesQ72817268
Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase. Role of reactive oxygen intermediatesQ72875744
Differences in the ingestion mechanisms of IgG and C3b particles in phagocytosis by neutrophilsQ72926323
Okadaic acid-induced actin assembly in neutrophils: role of protein phosphatasesQ72971147
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectphagocytosisQ184726
P1104number of pages16
P304page(s)1037-1052
P577publication date1996-03-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleNa+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases
P478volume132

Reverse relations

cites work (P2860)
Q35416592A FRET-based DNA biosensor tracks OmpR-dependent acidification of Salmonella during macrophage infection
Q46308399Amiloride interferes with platelet- activating factor-induced respiratory burst and MMP-9 release in bovine neutrophils independent of Na+/H+ exchanger 1.
Q94332140Attenuation of postcardioplegia injury with inhibitors of the sodium-hydrogen exchanger
Q91801658Benzotriazine Di-Oxide Prodrugs for Exploiting Hypoxia and Low Extracellular pH in Tumors
Q37901880Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines.
Q38793715Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects
Q43183643Effect of inhibitors of Na+/H+-exchange and gastric H+/K+ ATPase on cell volume, intracellular pH and migration of human polymorphonuclear leucocytes.
Q40939856Essential requirement of cytosolic phospholipase A(2) for activation of the H(+) channel in phagocyte-like cells
Q57364728Fc receptor-mediated phagocytosis
Q37465971Fever-range hyperthermia improves the anti-apoptotic effect induced by low pH on human neutrophils promoting a proangiogenic profile.
Q41168261Galpha12 differentially regulates Na+-H+ exchanger isoforms.
Q73485907Induction of Tyrosine Phosphorylation and Na+/H+Exchanger Activation during Shrinkage of Human Neutrophils
Q30438011Inhibition of Na+/H+ exchanger enhances low pH-induced L-selectin shedding and beta2-integrin surface expression in human neutrophils.
Q53836643Integrin-based diffusion barrier separates membrane domains enabling the formation of microbiostatic frustrated phagosomes.
Q42476225Lipopolysaccharide enhances FcgammaR-dependent functions in vivo through CD11b/CD18 up-regulation
Q41449511Modulation of innate and acquired immunity by an estrogenic dose of genistein in gonadectomized cats
Q46913667N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice
Q27024913Na+-H+ exchanger-1 (NHE1) regulation in kidney proximal tubule
Q40033025Na+/H+ exchange and pH regulation in the control of neutrophil chemokinesis and chemotaxis
Q38562432Neutrophil activation and periodontal tissue injury.
Q73681850Neutrophil intracellular pH and phagocytosis after thermal trauma
Q46620423Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2.
Q27015034Phosphatidylserine receptors: enhancers of enveloped virus entry and infection
Q36399226Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.
Q41959574Platelet-activating factor increases pH(i) in bovine neutrophils through the PI3K-ERK1/2 pathway
Q42159389Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades.
Q38692378Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains.
Q30491090Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

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