Pharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance

scientific article published on December 2010

Pharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1026589421
P356DOI10.1007/S10354-010-0848-4
P698PubMed publication ID21170698
P5875ResearchGate publication ID225156701

P2093author name stringMatthias Unger
P2860cites workEffects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazideQ24651117
Effects of St. John's wort on irinotecan metabolismQ33184162
Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.Q33907273
Inhibition of human cytochromes P450 by components of Ginkgo bilobaQ34337497
In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypesQ34419646
Hyperforin in St. John's wort drug interactionsQ34494412
St John's wort (Hypericum perforatum): drug interactions and clinical outcomesQ34976869
Interaction of St John's wort with conventional drugs: systematic review of clinical trialsQ35615173
Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo bilobaQ35765836
Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patientsQ35846658
Effects of dietary factors on drug transport and metabolism: the impact on dosage guidelines in transplant patientsQ37395763
The drug transporter-metabolism alliance: uncovering and defining the interplayQ37485904
Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily membersQ41376777
Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatinQ43830741
Impact of St John's wort treatment on the pharmacokinetics of tacrolimus and mycophenolic acid in renal transplant patientsQ44362349
Effect of St. John's wort on the pharmacokinetics of theophylline in healthy volunteersQ44697443
St John's wort induces both cytochrome P450 3A4-catalyzed sulfoxidation and 2C19-dependent hydroxylation of omeprazoleQ44787217
Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferasesQ44904677
Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteersQ45029658
In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto.Q45146006
Lack of effect of Ginkgo biloba on voriconazole pharmacokinetics in Chinese volunteers identified as CYP2C19 poor and extensive metabolizersQ46082217
Effect of silymarin on the pharmacokinetics of losartan and its active metabolite E-3174 in healthy Chinese volunteersQ46120062
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extractQ46459610
Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecanQ46797231
Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrateQ46908034
The effect of silymarin on oral nifedipine pharmacokineticsQ46925084
Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)Q73145709
Interaction of Hypericum perforatum (St. John's wort) with cyclosporin A metabolism in a patient after liver transplantationQ73246112
Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha)Q73553912
P433issue21-22
P407language of work or nameGermanQ188
P921main subjectpharmacokineticsQ323936
P304page(s)571-577
P577publication date2010-12-01
P1433published inWiener Medizinische WochenschriftQ2568998
P1476titlePharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance
P478volume160

Reverse relations

cites work (P2860)
Q83274402Drug interactions with herbal medicines
Q40727097Drug safety aspects of herbal medicinal products
Q38122439Pharmacokinetic drug interactions involving Ginkgo biloba
Q36190989Pharmacokinetics, toxicity, and cytochrome P450 modulatory activity of plumbagin
Q33908231Valerian: no evidence for clinically relevant interactions.
Q83970457[Drug-drug interactions in antirheumatic treatment]

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