ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

scientific article published on April 2017

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELL.2017.03.020
P932PMC publication ID5443414
P698PubMed publication ID28388412

P50authorDouglas R. GreenQ19667788
Andreas LinkermannQ30225182
P2093author name stringPatrick Fitzgerald
Yi-Nan Gong
Jan Ulrich Becker
Mao Yang
Cliff Guy
Hannes Olauson
P2860cites workRNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.Q38946818
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission MachineryQ38964693
Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposureQ38987723
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.Q38987871
Necroptosis in development, inflammation and disease.Q39044997
Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.Q40456100
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLsQ41057373
Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinaseQ42725146
Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it.Q43084271
ESCRT machinery is required for plasma membrane repairQ50462403
Lactadherin binding and phosphatidylserine expression on cell surface-comparison with annexin A5.Q50726001
The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.Q52783953
The ESCRT machinery: a cellular apparatus for sorting and scission.Q53286462
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.Q54464120
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinaseQ24302381
Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cellsQ24307778
Calcium-dependent phospholipid scrambling by TMEM16FQ24308774
An outline of necrosome triggersQ26751108
The two faces of receptor interacting protein kinase-1Q26853682
Damage control: cellular mechanisms of plasma membrane repairQ27022016
Structural insights into RIP3-mediated necroptotic signalingQ27686926
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosisQ28584976
Survival function of the FADD-CASPASE-8-cFLIP(L) complexQ28589465
RIP3 mediates the embryonic lethality of caspase-8-deficient miceQ29617723
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLQ30623992
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells.Q30679385
Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.Q34413744
Programmed necrosis in inflammation: Toward identification of the effector moleculesQ34520528
Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repairQ35099073
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3Q35781701
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and AblQ36365371
Structure and membrane remodeling activity of ESCRT-III helical polymersQ36386351
Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes NecroptosisQ36626724
Cell-specific translational profiling in acute kidney injuryQ37609662
Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapseQ37629486
The distribution and function of phosphatidylserine in cellular membranesQ37700664
Necrosome core machinery: MLKL.Q38799137
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors.Q38801542
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)286-300.e16
P577publication date2017-04-01
P1433published inCellQ655814
P1476titleESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
P478volume169