The mammalian Fizzy and Fizzy-related genes are regulated at the transcriptional and post-transcriptional levels

scientific article published on December 1999

The mammalian Fizzy and Fizzy-related genes are regulated at the transcriptional and post-transcriptional levels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-5793(99)01640-3
P698PubMed publication ID10606752

P50authorTamar ListovskyQ57045134
P2093author name stringBrandeis M
Inbal N
Listovsky T
P2860cites workA novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4Q24305321
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosisQ24656114
Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic eventsQ24683053
Regulation of APC activity by phosphorylation and regulatory factorsQ24683455
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindleQ27931239
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complexQ27933305
Cohesins: chromosomal proteins that prevent premature separation of sister chromatidsQ27934146
Cyclin is degraded by the ubiquitin pathwayQ28131704
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1Q28282074
Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy familyQ28288497
The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylationQ29615268
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1pQ29615276
Yeast Hct1 is a regulator of Clb2 cyclin proteolysisQ29618399
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin BQ29620071
The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiaeQ29620201
Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells.Q31107812
Regulation of the APC and the exit from mitosisQ33772649
Fission yeast Cut2 required for anaphase has two destruction boxes.Q33887593
Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.Q34444604
The WD-40 repeatQ36379533
Coordinated synthesis and degradation of cdc2 in the mammalian cell cycleQ36937643
Interaction Site of GTP Binding Gh (Transglutaminase II) with Phospholipase CQ38289357
Upstream stimulatory factor regulates expression of the cell cycle-dependent cyclin B1 gene promoterQ38295894
A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2Q40020877
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complexQ40919505
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extractsQ41883819
Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocyclesQ47072070
Proteolytic ratchets that control progression through mitosisQ47721256
The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosisQ47889973
Phosphorylation of the cyclosome is required for its stimulation by Fizzy/cdc20.Q48914490
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)350-354
P577publication date1999-12-01
P1433published inFEBS LettersQ1388051
P1476titleThe mammalian Fizzy and Fizzy-related genes are regulated at the transcriptional and post-transcriptional levels
P478volume463

Reverse relations

cites work (P2860)
Q36189504Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.
Q24530195Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1
Q40707197Fizzy-related RNA expression patterns in mammalian development and cell lines
Q24610309Mammalian Cdh1/Fzr mediates its own degradation
Q28206426Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation
Q36975260PTTG: an important target gene for ovarian cancer therapy
Q47070115Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2.
Q24545581Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis
Q40873768TSH regulates a gene expression encoding ERp29, an endoplasmic reticulum stress protein, in the thyrocytes of FRTL-5 cells.

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