Targeting of the molecular chaperone oxygen-regulated protein 150 (ORP150) to mitochondria and its induction by cellular stress

scientific article published on 19 December 2007

Targeting of the molecular chaperone oxygen-regulated protein 150 (ORP150) to mitochondria and its induction by cellular stress is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00400.2007
P698PubMed publication ID18094145
P5875ResearchGate publication ID5755192

P2093author name stringRick G Schnellmann
David D Arrington
P2860cites work150-kDa oxygen-regulated protein (ORP150) suppresses hypoxia-induced apoptotic cell deathQ22008804
150-kDa oxygen-regulated protein (ORP150) functions as a novel molecular chaperone in MDCK cellsQ22254183
Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunctionQ24294402
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein, ORP150Q24317647
150-kD oxygen-regulated protein is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxia and modified low density lipoproteinQ24561945
Production of three distinct mRNAs of 150 kDa oxygen-regulated protein (ORP150) by alternative promoters: preferential induction of one species under stress conditionsQ28144904
ORP150 protects against hypoxia/ischemia-induced neuronal deathQ28202922
ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell deathQ28270718
Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicityQ28364460
Marked, sustained expression of a novel 150-kDa oxygen-regulated stress protein, in severely ischemic mouse neuronsQ28506938
Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brainQ28578695
ORP150/HSP12A regulates Purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar developmentQ28585440
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein responseQ28611502
The hsp110 and Grp1 70 stress proteins: newly recognized relatives of the Hsp70sQ34068953
A mitochondrial specific stress response in mammalian cellsQ34090940
Antitumor effect of reduction of 150-kDa oxygen-regulated protein expression in human prostate cancer cellsQ34426603
Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.Q36167355
Patterns of atrophy in pathologically confirmed FTLD with and without motor neuron degenerationQ37363799
Role of calcium-activated neutral protease (calpain) in cell death in cultured neonatal rat cardiomyocytes during metabolic inhibitionQ39380886
Hypoxia selects for high-metastatic Lewis lung carcinoma cells overexpressing Mcl-1 and exhibiting reduced apoptotic potential in solid tumorsQ40358319
150-kD oxygen-regulated protein is an essential factor for insulin releaseQ40433036
Abundant expression of 150-kDa oxygen-regulated protein in mouse pancreatic beta cells is correlated with insulin secretionQ40900243
Ethidium bromide-induced inhibition of mitochondrial gene transcription suppresses glucose-stimulated insulin release in the mouse pancreatic beta-cell line betaHC9.Q41020684
Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell deathQ44097741
ORP150 (150 kDa oxygen regulated protein) suppressed neuronal cell deathQ44344052
The chaperoning properties of mouse grp170, a member of the third family of hsp70 related proteinsQ44692749
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperonesQ47069260
ORP150 ameliorates ischemia/reperfusion injury from middle cerebral artery occlusion in mouse brainQ47273745
150-kDa oxygen-regulated protein attenuates myocardial ischemia-reperfusion injury in rat heartQ47842783
Calcium transport and inner mitochondrial membrane damage in renal cortical mitochondria.Q51826243
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmolecular chaperonesQ422496
P304page(s)C641-50
P577publication date2007-12-19
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleTargeting of the molecular chaperone oxygen-regulated protein 150 (ORP150) to mitochondria and its induction by cellular stress
P478volume294

Reverse relations

cites work (P2860)
Q35293263Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress
Q43050228Calpain 10 homology modeling with CYGAK and increased lipophilicity leads to greater potency and efficacy in cells
Q28567446Calpain 10 is required for cell viability and is decreased in the aging kidney
Q38797885Dietary restriction: could it be considered as speed bump on tumor progression road?
Q31080106Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells
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Q37788639Genetics of childhood-onset inflammatory bowel disease
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Q37655066Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD)
Q35674605Mitochondrial calpain 10 is degraded by Lon protease after oxidant injury
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Q26765920Unfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic Implications

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