Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain

scientific article published on 2 December 2004

Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M411768200
P698PubMed publication ID15576369
P5875ResearchGate publication ID8152030

P50authorCynthia B CohenQ96754674
P2093author name stringJack L Arbiser
Daniel J Brat
Baskaran Govindarajan
Emma Murad
Francesca Cerimele
Marie Csete
William D Martin
Chunsik Lee
Toshiyuki Yamamoto
Benjamin Lefkove
Karin Litani
Matthew Nunnelley
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A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cellsQ28204697
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34Q28245141
Differential cellular expression of neurotrophins in cortical tubers of the tuberous sclerosis complexQ28360959
Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic backgroundQ28507548
Enhanced cardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified TSC2 transgeneQ28508426
Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)Q28577658
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathwayQ28646919
A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver diseaseQ33972858
Evidence That Lymphangiomyomatosis Is Caused by TSC2 Mutations: Chromosome 16p13 Loss of Heterozygosity in Angiomyolipomas and Lymph Nodes from Women with LymphangiomyomatosisQ34385154
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblastsQ34418354
Causes of Death in Patients With Tuberous SclerosisQ34794286
Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosisQ35789048
Oxygen-mediated regulation of skeletal muscle satellite cell proliferation and adipogenesis in cultureQ40775027
V-Ha-Ras overexpression induces superoxide production and alters levels of primary antioxidant enzymesQ40780906
Role of stem cell factor and monocyte chemoattractant protein-1 in the interaction between fibroblasts and mast cells in fibrosisQ40802755
Involvement of p70 S6 kinase in bone morphogenetic protein signaling: vascular endothelial growth factor synthesis by bone morphogenetic protein-4 in osteoblastsQ42831127
Regulation of PDGF production and ERK activation by estrogen is associated withTSC2gene expressionQ44406676
CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosisQ44650088
Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis.Q45873944
Identification of cDNAs Induced by the Tumor SuppressorTsc2Gene Using a Conditional Expression System inTsc2Mutant (Eker) Rat Renal Carcinoma CellsQ47907209
P433issue7
P407language of work or nameEnglishQ1860
P921main subjecttuberous sclerosisQ1362721
P304page(s)5870-5874
P577publication date2004-12-02
P1433published inJournal of Biological ChemistryQ867727
P1476titleTransgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain
P478volume280

Reverse relations

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