| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.273.21.13280 |
| P698 | PubMed publication ID | 9582373 |
| P2093 | author name string | R L Erikson | |
| H Greulich | |||
| P2860 | cites work | Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor | Q24305821 |
| Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals | Q24314293 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2. | Q24602577 | ||
| p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest | Q28258615 | ||
| Cyclin D1 is a nuclear protein required for cell cycle progression in G1 | Q28269145 | ||
| The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product | Q28316871 | ||
| p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
| Cancer cell cycles | Q29547756 | ||
| MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo | Q29615244 | ||
| Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells | Q29618480 | ||
| Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1. | Q30450197 | ||
| Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase | Q30450248 | ||
| Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase | Q30454074 | ||
| Biochemical and biological analysis of Mek1 phosphorylation site mutants | Q34446879 | ||
| Function of a human cyclin gene as an oncogene | Q34994859 | ||
| Constitutive activation of Mek1 by mutation of serine phosphorylation sites | Q35756491 | ||
| Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells | Q36552538 | ||
| Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1. | Q36568076 | ||
| Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation | Q36682210 | ||
| Phorbol ester stimulates a protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product | Q37183425 | ||
| Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes. | Q38292576 | ||
| A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins | Q38295120 | ||
| Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1. | Q40022664 | ||
| High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. | Q40023426 | ||
| Raf meets Ras: completing the framework of a signal transduction pathway | Q40682071 | ||
| Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells | Q41145783 | ||
| Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts | Q41176644 | ||
| Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts | Q42807624 | ||
| Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle | Q42813101 | ||
| Cooperating oncogenes converge to regulate cyclin/cdk complexes. | Q53445613 | ||
| Signal transduction. How receptors turn Ras on. | Q55066288 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 13280-13288 | |
| P577 | publication date | 1998-05-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | An analysis of Mek1 signaling in cell proliferation and transformation | |
| P478 | volume | 273 |
| Q35602157 | ANGPTL3 is a novel biomarker as it activates ERK/MAPK pathway in oral cancer |
| Q58450931 | Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling |
| Q34429251 | Annexin A10 in human oral cancer: biomarker for tumoral growth via G1/S transition by targeting MAPK signaling pathways |
| Q38862698 | Cavin-2 in oral cancer: A potential predictor for tumor progression |
| Q57807339 | Cytoprotective Effects of Natural Compounds against Oxidative Stress |
| Q21091084 | Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: its implications to therapy |
| Q43846280 | Dual-regulated expression technology: a new era in the adjustment of heterologous gene expression in mammalian cells |
| Q24629604 | ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression |
| Q44219422 | Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy |
| Q42819058 | Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1. |
| Q57369366 | Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis |
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| Q44769178 | Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: lack of effect of ERK. |
| Q40923873 | MAP kinase cascade is required for p27 downregulation and S phase entry in fibroblasts and epithelial cells |
| Q34354215 | MEK Inhibition Potentiates the Activity of Hsp90 Inhibitor 17-AAG against Pancreatic Cancer Cells |
| Q24291824 | MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway |
| Q34991305 | Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations |
| Q40872982 | Oncogenic signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27. |
| Q41734805 | Peroxisome proliferator-activated receptor gamma ligands inhibit retinoblastoma phosphorylation and G1--> S transition in vascular smooth muscle cells |
| Q40808389 | Phosphoinositide 3-kinase-dependent regulation of interleukin-3-induced proliferation: involvement of mitogen-activated protein kinases, SHP2 and Gab2. |
| Q73110188 | Posttranslational regulation of proteins by fusions to steroid-binding domains |
| Q73643318 | Proliferation of intimal smooth muscle cells. Attenuation of basic fibroblast growth factor 2-stimulated proliferation is associated with increased expression of cell cycle inhibitors |
| Q39352683 | Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr |
| Q34326213 | Ras and Rho regulation of the cell cycle and oncogenesis |
| Q42795734 | Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells |
| Q37323586 | Regulated multicistronic expression technology for mammalian metabolic engineering |
| Q42240189 | Regulation of cyclin-dependent kinase (Cdk) 2 Thr-160 phosphorylation and activity by mitogen-activated protein kinase in late G1 phase |
| Q36300940 | Reversible modulation of SIRT1 activity in a mouse strain |
| Q42796164 | Simultaneous downregulation of CDK inhibitors p18(Ink4c) and p27(Kip1) is required for MEN2A-RET-mediated mitogenesis |
| Q38658688 | Streptogramin- and tetracycline-responsive dual regulated expression of p27(Kip1) sense and antisense enables positive and negative growth control of Chinese hamster ovary cells |
| Q59131878 | Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma |
| Q28301955 | The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition |
| Q36002446 | The elements of human cyclin D1 promoter and regulation involved |
| Q41717437 | The expression and function of miR-424 in infantile skin hemangioma and its mechanism |
| Q33959204 | The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes |
| Q33952356 | The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells. |
| Q42114458 | Time Course Expression Analysis of 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole Induction of Cytoprotection in Human Endothelial Cells |
| Q54362376 | microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris. |
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