| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M611129200 |
| P698 | PubMed publication ID | 17374607 |
| P50 | author | Kang-Yell Choi | Q23901867 |
| Young Nyun Park | Q59679954 | ||
| Young-Joon Surh | Q91713697 | ||
| Soung-Hoo Jeon | Q126285827 | ||
| P2093 | author name string | Eek-Hoon Jho | |
| Sewoon Kim | |||
| Ju-Yong Yoon | |||
| Woo-Jeong Jeong | |||
| P2860 | cites work | Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin | Q24313571 |
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC | Q24336321 | ||
| The links between axin and carcinogenesis | Q24672469 | ||
| Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver | Q24680214 | ||
| A genetic model for colorectal tumorigenesis | Q27860582 | ||
| Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells | Q27860717 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas | Q28213290 | ||
| The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation | Q28244304 | ||
| Induction of tyrosine phosphorylation and association of beta-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence | Q28244489 | ||
| Association of the APC tumor suppressor protein with catenins | Q28257313 | ||
| Genetic alterations during colorectal-tumor development | Q28281200 | ||
| Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta | Q28505773 | ||
| APC inhibits ERK pathway activation and cellular proliferation induced by RAS | Q28510825 | ||
| Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors | Q28640916 | ||
| Wnt signaling: a common theme in animal development | Q29547527 | ||
| Truncated form of beta-catenin and reduced expression of wild-type catenins feature HepG2 human liver cancer cells. | Q33833436 | ||
| Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas | Q34067016 | ||
| Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation | Q34081815 | ||
| Blocking oncogenic Ras signaling for cancer therapy | Q34311585 | ||
| Molecular causes of colon cancer | Q34680639 | ||
| Oncogenic Ras and its role in tumor cell invasion and metastasis | Q35690261 | ||
| The significance of the Wnt pathway in the pathology of human cancers | Q35809118 | ||
| The MAPK signalling pathways and colorectal cancer | Q36111490 | ||
| Regulation of Wnt signaling by protein-protein interaction and post-translational modifications | Q36415188 | ||
| Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas | Q36557348 | ||
| Beta-catenin mutations in cell lines established from human colorectal cancers | Q36586200 | ||
| Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression | Q39446786 | ||
| Wnt signaling controls the phosphorylation status of beta-catenin. | Q42162259 | ||
| Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation | Q42472178 | ||
| Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts | Q42829238 | ||
| Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis | Q43411713 | ||
| Ectopic expression of Axin blocks neuronal differentiation of embryonic carcinoma P19 cells | Q44303790 | ||
| Stable suppression of tumorigenicity by virus-mediated RNA interference | Q45730805 | ||
| Differential modification of Ras proteins by ubiquitination | Q46968371 | ||
| P433 | issue | 19 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 14482-14492 | |
| P577 | publication date | 2007-03-20 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin | |
| P478 | volume | 282 |
| Q61444296 | A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer |
| Q37234348 | A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes. |
| Q59336793 | A small molecule approach to degrade RAS with EGFR repression is a potential therapy for KRAS mutation-driven colorectal cancer resistance to cetuximab |
| Q38252534 | AXIN1 and AXIN2 variants in gastrointestinal cancers |
| Q28534819 | Alternative signaling pathways as potential therapeutic targets for overcoming EGFR and c-Met inhibitor resistance in non-small cell lung cancer |
| Q40888327 | An AXIN2 Mutant Allele Associated With Predisposition to Colorectal Neoplasia Has Context-Dependent Effects on AXIN2 Protein Function |
| Q39866515 | Axin localizes to mitotic spindles and centrosomes in mitotic cells |
| Q39552816 | Axin1 expression facilitates cell death induced by aurora kinase inhibition through PARP activation |
| Q28569321 | Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway |
| Q53447865 | Comparative study of LHX8 expression between odontoma and dental tissue-derived stem cells. |
| Q90709733 | Deletion of Axin1 in condylar chondrocytes leads to osteoarthritis-like phenotype in temporomandibular joint via activation of β-catenin and FGF signaling |
| Q36811339 | Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24. |
| Q51839740 | Direct GSK-3β inhibition enhances mesenchymal stromal cell migration by increasing expression of β-PIX and CXCR4. |
| Q37169064 | Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity |
| Q34449946 | Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition |
| Q61802821 | Growth inhibition and apoptosis in colorectal cancer cells induced by Vitamin D-Nanoemulsion (NVD): involvement of Wnt/β-catenin and other signal transduction pathways |
| Q54976921 | Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway. |
| Q36356328 | K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis |
| Q37697209 | KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer |
| Q38088654 | Mechanisms of RAS/β-catenin interactions |
| Q85962927 | MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1 |
| Q40096921 | Mitogen-activated protein kinase p38 regulates the Wnt/cyclic GMP/Ca2+ non-canonical pathway. |
| Q30497951 | Quantitative automated microscopy (QuAM) elucidates growth factor specific signalling in pain sensitization |
| Q54517954 | Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis. |
| Q42138343 | Regulated proteolysis of Candida albicans Ras1 is involved in morphogenesis and quorum sensing regulation |
| Q36050149 | Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation |
| Q35181226 | The effect of 1,25 dihydroxyvitamin D3 treatment on the mRNA levels of β catenin target genes in mice with colonic inactivation of both APC alleles |
| Q30989535 | The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2) |
| Q33391576 | Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway |
| Q60907514 | WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation |
| Q39214717 | Wnt3a regulates proliferation, apoptosis and function of pancreatic NIT-1 beta cells via activation of IRS2/PI3K signaling |
| Q36217822 | β-Asarone Rescues Pb-Induced Impairments of Spatial Memory and Synaptogenesis in Rats |
| Q47110007 | β-Catenin Accumulation Is Associated With Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-Renewal |
| Q58563665 | β-Catenin-RAS interaction serves as a molecular switch for RAS degradation via GSK3β |
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