Crystallization of the first three domains of the human insulin-like growth factor-1 receptor

scientific article published on December 1997

Crystallization of the first three domains of the human insulin-like growth factor-1 receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/PRO.5560061223
P932PMC publication ID2143606
P698PubMed publication ID9416620
P5875ResearchGate publication ID227706343

P2093author name stringCosgrove LJ
Elleman TC
McKern NM
Ward CW
Frenkel MJ
Garrett TP
Ivancic N
Lou M
Bentley JD
Lovrecz GO
Verkuylen A
P2860cites workaxl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseQ24310364
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene productQ27860841
All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptorQ28626012
Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chainsQ33392787
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificityQ33880454
Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneityQ36765148
Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinantsQ38322445
The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity. Evidence from receptor chimerasQ38338637
The science of macromolecular crystallizationQ40427597
Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand bindingQ41098705
Mapping of an NH2-terminal ligand binding site of the insulin receptor by alanine scanning mutagenesisQ41368833
Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the alpha-subunit of the insulin receptor. Identification of a new insulin-binding domain in the insulin receptorQ41428446
Identification of a disulfide bridge connecting the alpha-subunits of the extracellular domain of the insulin receptorQ41589386
Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptorsQ41661260
Changing the insulin receptor to possess insulin-like growth factor I ligand specificityQ41725096
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activityQ42070889
A soluble insulin-like growth factor I receptor that induces apoptosis of tumor cells in vivo and inhibits tumorigenesis.Q42809660
Structural organization of the human insulin receptor ectodomain.Q52409983
On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.Q52464078
Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2Q56915399
Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptorsQ70550599
Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor alpha subunitQ70937602
Purification and properties of insulin receptor ectodomain from large-scale mammalian cell cultureQ71363680
Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptorQ71763596
Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragmentQ71903483
Protein microheterogeneity and crystal habits: the case of epidermal growth factor receptor isoforms as isolated in a multicompartment electrolyzer with isoelectric membranesQ72783765
The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomainQ73876950
P433issue12
P921main subjectpreproinsulinQ7240673
P304page(s)2663-2666
P577publication date1997-12-01
P1433published inProtein ScienceQ7251445
P1476titleCrystallization of the first three domains of the human insulin-like growth factor-1 receptor
P478volume6

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cites work (P2860)
Q77779611A third fibronectin type III domain in the extracellular region of the insulin receptor family
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Q33408460Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo
Q40947522Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain
Q27764901Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor
Q38335851Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.
Q30389131Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor
Q30414571Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications
Q41632332Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor
Q34944353The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity
Q57793591The signalling conformation of the insulin receptor ectodomain

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