Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk

scientific article published on 26 March 2016

Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk is …
instance of (P31):
scholarly articleQ13442814
editorialQ871232

External links are
P356DOI10.1007/S00204-016-1698-7
P932PMC publication ID4830874
P698PubMed publication ID27017488

P50authorMarcel LeistQ42136322
Bob van de WaterQ47087808
P2093author name stringBob van de Water
Jan Hengstler
Hennicke Kamp
Mardas Daneshian
P2860cites workHighlight report: towards the replacement of in vivo repeated dose systemic toxicity testingQ59878255
The dawning of a new age of toxicology.Q40081577
Quantitative Adverse Outcome Pathway Analysis of Hatching in Zebrafish with CuO NanoparticlesQ40530647
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseasesQ40881866
Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structureQ41387646
The ChemScreen project to design a pragmatic alternative approach to predict reproductive toxicity of chemicalsQ41471602
A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogensQ42704018
Stress response pathways, toxicity pathways and adverse outcome pathwaysQ44261396
Toxicity testing in the 21st century beyond environmental chemicalsQ44858463
Integrated Testing Strategies (ITS) for safety assessment.Q45955833
Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regenerationQ46550945
Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA).Q46833337
The SEURAT-1 approach towards animal free human safety assessment.Q51037430
Consensus report on the future of animal-free systemic toxicity testingQ27008968
Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision MakingQ28082423
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanismsQ28530398
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessmentQ28651094
Supporting read-across using biological dataQ28834626
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitorsQ30662775
Using ToxCastâ„¢ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of DepartureQ31006619
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathwayQ33883400
The human toxome projectQ34465807
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposesQ35024730
Toxicogenomics directory of chemically exposed human hepatocytesQ35423042
Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration.Q36456362
Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships.Q36723032
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Q37121662
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.Q37981574
An overview of transcriptional regulation in response to toxicological insult.Q38038498
Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessmentQ38180817
Current approaches and future role of high content imaging in safety sciences and drug discoveryQ38229861
SEURAT-1 liver gold reference compounds: a mechanism-based reviewQ38268013
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approachQ38319756
Systems Toxicology: The Future of Risk AssessmentQ38785209
Toward a unifying strategy for the structure-based prediction of toxicological endpointsQ38944440
SEURAT: Safety Evaluation Ultimately Replacing Animal Testing--recommendations for future research in the field of predictive toxicologyQ39092703
Read-across approaches--misconceptions, promises and challenges aheadQ39103424
Toward Good Read-Across Practice (GRAP) guidanceQ40007546
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P304page(s)1021-1024
P577publication date2016-03-26
P1433published inArchives of ToxicologyQ635837
P1476titleHighlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk
P478volume90